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Case report: Leishmaniasis of the upper lip


Case report: Leishmaniasis of the upper lip



Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics 104(5): 659-661



ISSN/ISBN: 1079-2104

PMID: 17656118

DOI: 10.1016/j.tripleo.2007.02.014

We report a case of leishmaniasis localized to the upper lip in a 77-year-old Italian man. The disease was characterized by a severe swelling which involved the right side of the upper lip. The swelling was slightly erythematous with crusts and scaling. Consistency was parenchymatous-hard. The lesion was asymptomatic. Histopathologic examination showed an inflammatory infiltrate consisting of lymphocytes, histiocytes, and plasma cells. Several Leishmania spp. amastigotes were observed in the cytoplasm of macrophages. Cultural examination on Novy-MacNeal-Nicolle medium was positive for Leishmania spp. Polymerase chain reaction was positive for Leishmania infantum. The patient was treated with i.m. N-methylglucamine antimonate, with complete remission in approximately 6 weeks. During follow-up of 9 months, no relapses were observed.

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Accession: 051963920

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