+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Chlorhexidine impregnated central venous catheter inducing an anaphylatic shock in the intensive care unit



Chlorhexidine impregnated central venous catheter inducing an anaphylatic shock in the intensive care unit



Heart Lung and Circulation 20(10): 669-670



Chlorhexidine, a bisbiguanide, is widely used as an antiseptic agent in medical practice as it has the greatest residual antimicrobial activity. Central venous catheters coated extraluminally with chlorhexidine have been made to reduce extraluminal contamination. By using both the chlorhexidine-alchohol skin preparation and antimicrobial-coated catheters during vascular cannulation, it can reduce catheter related bloodstream significantly [1]. The reduction in infection rate is especially vital in critically ill patients who require long-term vascular access. Adverse reactions to chlorhexidine are rare and uncommon, and have been under-recognised as a cause of anaphylaxis. There are several reports of allergic reactions following exposure to chlorhexidine. We report of a case of anaphylaxis shock requiring cardiopulmonary resuscitation during the placement of a chlorhexidine impregnated central venous catheters.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052066391

Download citation: RISBibTeXText

PMID: 21036666

DOI: 10.1016/j.hlc.2010.10.001


Related references

Double-lumen central venous catheters impregnated with chlorhexidine and silver sulfadiazine to prevent catheter colonisation in the intensive care unit setting: a prospective randomised study. Journal of Hospital Infection 72(3): 227-233, 2009

Effectiveness of Minocycline and Rifampin vs Chlorhexidine and Silver Sulfadiazine-Impregnated Central Venous Catheters in Preventing Central Line-Associated Bloodstream Infection in a High-Volume Academic Intensive Care Unit: A Before and after Trial. Journal of the American College of Surgeons 221(3): 739-747, 2015

Anaphylactic shock associated with a central venous catheter impregnated with chlorhexidine and silver sulfadiazine. Masui. Japanese Journal of Anesthesiology 47(5): 556-561, 1998

Evaluation of antiseptic-impregnated central venous catheters for prevention of catheter-related infection in intensive care unit patients. Diagnostic Microbiology & Infectious Disease 38(1): 1-5, 2000

Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: a before-after trial. Surgical Infections 8(4): 445-454, 2007

Chlorhexidine-Impregnated Dressings and Prevention of Catheter-Associated Bloodstream Infections in a Pediatric Intensive Care Unit. Critical Care Nurse 36(6): E1-E7, 2016

Comparison of Oligon catheters and chlorhexidine-impregnated sponges with standard multilumen central venous catheters for prevention of associated colonization and infections in intensive care unit patients: a multicenter, randomized, controlled study. Critical Care Medicine 40(2): 420-429, 2012

Which central venous catheters have the highest rate of catheter-associated deep venous thrombosis: a prospective analysis of 2,128 catheter days in the surgical intensive care unit. Journal of Trauma and Acute Care Surgery 74(2): 454-60; Discussion 461-2, 2013

Anaphylaxis to chlorhexidine-impregnated central venous catheter. Anaesthesia and Intensive Care 31(6): 697-698, 2003

Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial. Annals of Internal Medicine 143(8): 570-580, 2005

Reduction of central venous catheter-related infection in cancer patients with severe neutropenia A prospective controlled randomized trial using a chlorhexidine and silver-sulfadiazine impregnated central venous line. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 41: 447, 2001

Central venous catheter-associated bloodstream infections in a pediatric intensive care unit: effect of the location of catheter insertion. Pediatric Critical Care Medicine 13(3): E176-E180, 2012

Reduction of catheter-related infections in neutropenic patients: a prospective controlled randomized trial using a chlorhexidine and silver sulfadiazine-impregnated central venous catheter. Annals of Hematology 84(4): 258-262, 2005

Severe anaphylactic reaction due to a chlorhexidine-impregnated central venous catheter. Anesthesiology 89(5): 1296-1298, 1998