+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Clinical and metabolic characteristics of polycystic ovary syndrome without polycystic ovary: a pilot study on Chinese women



Clinical and metabolic characteristics of polycystic ovary syndrome without polycystic ovary: a pilot study on Chinese women



Fertility and Sterility 90(4): 1139-1143



To demonstrate clinical features of a patient subgroup presenting with polycystic ovary syndrome (PCOS) without polycystic ovary morphology. Retrospective study. Hospital-based IVF center. In the present study, 876 PCOS patients were selected from women who visited the Reproductive Medicine Center at Shandong Provincial Hospital, Shandong University, between September 2004 and October 2006. Women with PCOS were divided into two groups based on ultrasound image: group A, PCOS patients with classic polycystic ovary (n = 800); group B, PCOS patients without polycystic ovary morphology (n = 76). The following available data were analyzed in the large cohort of women: body height, weight, waistline, hip circumference, hirsutism scores, family history, serum sex hormone levels, blood glucose levels, insulin levels, and blood lipid levels. An oral glucose tolerance test and insulin release test were performed for each woman. After overnight fasting, blood samples were collected to determine fasting blood glucose, LH, FSH, T, PRL, E(2), and blood lipid levels. Height, weight, waistline, hip circumference, Ferriman-Gallwey grade for hirsutism, gonadal hormone results, blood lipid level, blood glucose tolerance, each-moment insulin level, and family history were determined for the two groups. No statistical difference was observed between groups in age, body height and weight, waistline, hip circumference, FSH, LH, PRL, E(2), each-moment blood glucose, and each-moment insulin. There were significantly higher hirsutism scores (6.31 +/- 6.44 vs. 4.18 +/- 4.96) and serum T levels (80.71 +/- 17.89 vs. 66.35 +/- 33.31) in group B than in group A. Cholesterol (4.99 +/- 1.01 vs. 4.70 +/- 0.91) and low-density lipoprotein (3.59 +/- 1.17 vs. 3.03 +/- 1.10) were both significantly higher in group B than in group A. In addition, significantly higher rates of diabetes mellitus and hypertension were observed in patients' first-grade relatives in group B than in group A. Patients with PCOS without polycystic ovaries had higher cholesterol and low-density lipoprotein and possibly had a higher incidence of developing long-term complications.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052106932

Download citation: RISBibTeXText

PMID: 17889857

DOI: 10.1016/j.fertnstert.2007.07.1375


Related references

Clinical characteristics, metabolic features, and phenotype of Chinese women with polycystic ovary syndrome: a large-scale case-control study. Archives of Gynecology and Obstetrics 287(3): 525-531, 2013

Prevalence of Polycystic Ovary Syndrome Phenotypes Using Updated Criteria for Polycystic Ovarian Morphology: An Assessment of Over 100 Consecutive Women Self-reporting Features of Polycystic Ovary Syndrome. Reproductive Sciences 21(8): 1034-1043, 2014

Endocrine and metabolic characteristics of polycystic ovary syndrome in Chinese women with different phenotypes. Clinical Endocrinology 76(3): 425-430, 2012

A pilot study of serum anti-Mullerian hormone in diagnosis of polycystic ovary syndrome based on 2012 Chinese polycystic ovary syndrome diagnosis criteria. Zhonghua Fu Chan Ke Za Zhi 50(11): 819-824, 2016

Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome. Clinical Endocrinology 66(4): 513-517, 2007

Drospirenone for the treatment of hirsute women with polycystic ovary syndrome: a clinical, endocrinological, metabolic pilot study. Journal of Clinical Endocrinology and Metabolism 89(6): 2817-2823, 2004

Analysis of clinical characteristics in large-scale Chinese women with polycystic ovary syndrome. Neuro Endocrinology Letters 28(6): 807-810, 2007

Epidemiological study of clinical characteristics of Chinese Han ethnic women with polycystic ovary syndrome. Zhonghua Fu Chan Ke Za Zhi 41(6): 375-379, 2006

A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndrome. Plos One 10(12): E0144072, 2016

High-sensitivity C-reactive protein (hs-CRP) levels and its relationship with components of polycystic ovary syndrome in Indian adolescent women with polycystic ovary syndrome (PCOS). Gynecological Endocrinology 30(11): 781-784, 2015

Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and nonobese women in the Croatian population. Collegium Antropologicum 37(2): 465-470, 2013

Health-related quality of life in women with polycystic ovary syndrome: a comparison with the general population using the Polycystic Ovary Syndrome Questionnaire (PCOSQ) and the Short Form-36 (SF-36). Gynecological Endocrinology 22(2): 80-86, 2006

There is no difference in the plasma cortisol level between women with body mass index (BMI) greater than or equal 25 kg/m² and polycystic ovary syndrome and the control group without polycystic ovary syndrome and BMI 25 kg/m². Przeglad Lekarski 73(4): 207-209, 2016

P698 Outcomes of Coh and Ivf between women with polycystic ovary syndrome and those with sonographic polycystic ovary only in GnRh antagonist cycles: comparative study. International Journal of Gynecology & Obstetrics 107: S613-S614, 2009

Statistical Genomic Approach Identifies Association between FSHR Polymorphisms and Polycystic Ovary Morphology in Women with Polycystic Ovary Syndrome. Biomed Research International 2015: 483726, 2016