+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Clinical evaluation of BIOXTRA in relieving signs and symptoms of dry mouth after head and neck radiotherapy of cancer patients at Seyed-al-Shohada Hospital, Isfahan, Iran



Clinical evaluation of BIOXTRA in relieving signs and symptoms of dry mouth after head and neck radiotherapy of cancer patients at Seyed-al-Shohada Hospital, Isfahan, Iran



Advanced Biomedical Research 1: 72



Radiotherapy of head and neck cancers causes acute and chronic xerostomia and acute mucositis. Xerostomia increases risk of radiation caries and affects on oral comfort, fit of prostheses, speech, swallowing, and the growth of caries-producing organisms. Salivary flow rate can be measured by asking patients some questions. There are different types of commercial synthetic saliva such as BIOXTRA, but until now, no one can effectively relieve xerostomia. We tried to design a clinical research on BIOXTRA efficacy for treating xerostomia. In this research, 58 patients with head and neck cancer (except salivary gland cancers) treated in Seyed-al-Shohada Hospital. The patients received at least 40-50 GY; and after 2 months of compilation treatment, they were evaluated by asking about having xerostomia. Before and after treatment with the BIOXTRA, the PH of the oral cavity, candida albicans, and lactobacillus counts measured and documented in laboratory. We used BIOXTRA for 2 weeks, 3 times daily, and then re-evaluated patients with some questions. The counts of candida albicans and lactobacilli statistically significant decreased. Xerostomia for most patients improved clinically during the day and night while PH of the oral cavity increased.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 052115917

Download citation: RISBibTeXText

PMID: 23326802


Related references

Relationship between breastfeeding factors and breast cancer in women referred to Seyed Al-Shohada Hospital in Isfahan, Iran. Iranian Journal of Nursing and Midwifery Research 21(6): 622-627, 2017

The comparison of perceived stress in idiopathic thrombocytopenic purpura patients referred to Seyed Al-Shohada Hospital with healthy people in Isfahan, Iran, 2013. International Journal of Hematology-Oncology and Stem Cell Research 9(2): 67-71, 2015

Clinical evaluation of a commercially available oral moisturizer in relieving signs and symptoms of xerostomia in postirradiation head and neck cancer patients and patients with Sjögren's syndrome. Journal of Otolaryngology 29(1): 28-34, 2000

Determination Relation of the Zinc Serum Level in Acute Leukemia Adult Patients with Mucositis and Neutropenic Prevalence before and after Treatment in Isfahan' Seyed-Al-Shohada Hospital, 2012-2013. Advanced Biomedical Research 7: 31, 2018

The Relationship between Self-esteem and Quality of Life of Patients with Idiopathic Thrombocytopenic Purpura at Isfahan's Sayed Al-Shohada Hospital, Iran, in 2013. International Journal of Hematology-Oncology and Stem Cell Research 10(2): 79-84, 2016

Survey of the effect of streptokinase on ventricular repolarization by examining the QT dispersion in patients with acute myocardial infraction in Seyed-Al-Shohada hospital, Urmia. Global Journal of Health Science 6(7 Spec No): 74-82, 2014

Validation of the Chinese version of the Head and Neck Patient Symptom Checklist for measuring nutrition impact symptoms during radiotherapy in patients with head and neck cancer. Supportive Care in Cancer 27(12): 4705-4711, 2019

Clinical warning signs and symptoms of head and neck cancer. Texas Dental Journal 117(6): 14-19, 2000

Explosive attack: Lessons learned in Seyed Al Shohada mosque attack, April 2008, Shiraz, Iran. Journal of Emergencies Trauma and Shock 5(4): 296-298, 2012

Translation and cross-cultural adaptation into Brazilian Portuguese of the Vanderbilt Head and Neck Symptom Survey version 2.0 (VHNSS 2.0) for the assessment of oral symptoms in head and neck cancer patients submitted to radiotherapy. Brazilian Journal of Otorhinolaryngology 81(6): 622-629, 2016

Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer". Radiation Oncology 13(1): 123, 2018

Can acupuncture prevent and manage dry mouth induced by radiotherapy in patients with head and neck cancer?. Focus on Alternative and Complementary Therapies 19(2): 92-93, 2014

Radiation-Induced Mucositis in Patients with Head and Neck Cancer: Should the Signs or the Symptoms be Measured?. Journal 81: F11, 2015

Acupuncture relieves symptoms of a dry mouth caused by radiotherapy for head and neck cancers. 2012

Evaluation of objective measures of smoking status--a prospective clinical study in a group of head and neck cancer patients treated with radiotherapy. Acta Oncologica 42(2): 154-159, 2003