+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparison of mixed venous oxygen saturation after in vitro calibration of pulmonary artery catheter with that of pulmonary arterial blood in patients undergoing living donor liver transplantation



Comparison of mixed venous oxygen saturation after in vitro calibration of pulmonary artery catheter with that of pulmonary arterial blood in patients undergoing living donor liver transplantation



Transplantation Proceedings 45(5): 1916-1919



Mixed venous saturation (SvO2) reflects the balance between oxygen delivery and consumption throughout the body. A multifunction pulmonary artery catheter (PAC) can monitor continuous SvO2 after in vitro calibration (CSvO2), obviating the need for in vivo calibration with pulmonary arterial blood. In critically ill patients CSvO2 has shown a good correlation with measured SvO2 of pulmonary arterial blood using co-oximetry (MSvO2). The aim of this study was to compare CSvO2 and MSvO2 in liver transplantation (OLT) recipients. We enrolled 44 OLT recipients for comparison with 24 coronary artery bypass graft (CABG) controls free of end-stage liver disease. After anesthetic induction, the PAC was inserted after in vitro calibration and CSvO2 and MSvO2 simultaneously measured. In OLT recipients, additional measurements of CSvO2 and MSvO2 were performed at anhepatic and postreperfusion phases. Pearson's correlation analysis was used to evaluate the correlation between the 2 measurements. A Bland-Altman analysis was used to determine precision of and bias between the 2 measurements. With ±3% regarded to be interchangeable. Cardiac output and intrapulmonary shunt in CABG patients were lower than among OLT recipients. OLT recipients, showed a significant correlation between CSvO2 and MSvO2, but the coefficients were different during the three phases of OLT (r = 0.597, 0.753, and 0.756). In addition, bias values between the two measurements were 6.0%, 6.4%, and 2.9% for the preanhepatic, anhepatic, and postreperfusion phases, respectively, with 29.5%, 31.8%, and 50% of them being interchangeable. In contrast CABG patients showed bias in -0.17% with 75% of measurements interchangeable. While in vitro calibration of the PAC can be used in CABG patients, MSvO2 is higher than CSvO2 in OLT recipients. Therefore, in vivo calibration with pulmonary arterial blood is necessary for accurate monitoring of SvO2 in OLT recipients.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052238388

Download citation: RISBibTeXText

PMID: 23769072

DOI: 10.1016/j.transproceed.2012.08.028


Related references

Predictive factors for usefulness of fiberoptic pulmonary artery catheter for continuous oxygen saturation in mixed venous blood monitoring in cardiac surgery. Anesthesia and Analgesia 85(1): 2, 1997

The accuracy of the continuous mixed venous oxygen saturation pulmonary artery catheter during cardiac surgery. Anesthesiology 71(3A): A382, 1989

Continuous monitoring of mixed venous oxygen saturation during exercise using fiberoptic pulmonary artery catheter. Kokyu to Junkan. Respiration & Circulation 38(8): 799-804, 1990

The oxygen saturation of blood in the venae cavae right heart chambers and pulmonary artery comparison of formulas to estimate mixed venous blood in healthy infants and children. Zeitschrift fuer Kardiologie 69(7): 504-507, 1980

Relationship between oxygen saturation of mixed venous blood and pressure in the pulmonary artery trunk in healthy humans and patients with heart defects. Human Physiology 37(4): 422-429, 2011

Gw29-e0859 Investigation of Central Venous Oxygen Saturation Substitutes Mixed Venous Oxygen Saturation in Postoperative Care of Congenital Heart Disease with Pulmonary Arterial Hypertension. Journal of the American College of Cardiology 72(16): C184-C185, 2018

Cardiac output measurement in patients undergoing liver transplantation: pulmonary artery catheter versus uncalibrated arterial pressure waveform analysis. Anesthesia and Analgesia 106(5): 1480-6 Table of Contents, 2008

Mixed Venous Oxygen Saturation Measured with an Abbot Oximetric Pulmonary Artery Catheter, and Instrumentation Laboratory Co-Oximeter after Resuscitation with Varying Concentrations of Hemoglobin-Based Oxygen Carrier in a Dog Hemorrhage Model. Anesthesiology Abstracts of Scientific Papers Annual Meeting (2001): Abstract No A-556, 2002

Ammonia content of mixed venous blood (obtained from pulmonary artery) and arterial blood in patients with pulmonary heart disease. Pneumonologia Polska 49(4): 287-290, 1981

Comparison of the USCOM ultrasound cardiac output monitor with pulmonary artery catheter thermodilution in patients undergoing liver transplantation. Liver Transplantation 14(7): 1038-1043, 2008

A comparison of two pulmonary artery mixed venous oxygen saturation catheters during the changing conditions of cardiac surgery. Journal of Cardiothoracic Anesthesia 3(3): 269-275, 1989

Comparison of central venous oxygen saturation and mixed venous oxygen saturation during liver transplantation. Anaesthesia 64(4): 378-382, 2009

Comparison of bench central and mixed pulmonary venous oxygen saturation in critically ill postsurgical patients. Minerva Anestesiologica 61(7-8): 285-291, 1995

Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension. Heart and Vessels 34(4): 688-697, 2019

Perforation of the right ventricle by a pulmonary artery catheter that continues to measure cardiac output and mixed venous saturation. Journal of Clinical Anesthesia 17(2): 124-127, 2005