+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparison of three screening tools to detect psoriatic arthritis in patients with psoriasis (CONTEST study)



Comparison of three screening tools to detect psoriatic arthritis in patients with psoriasis (CONTEST study)



British Journal of Dermatology 168(4): 802-807



Multiple questionnaires to screen for psoriatic arthritis (PsA) have been developed but the optimal screening questionnaire is unknown. To compare three PsA screening questionnaires in a head-to-head study using CASPAR (the Classification Criteria for Psoriatic Arthritis) as the gold standard. This study recruited from 10 U.K. secondary care dermatology clinics. Patients with a diagnosis of psoriasis, not previously diagnosed with PsA, were given all three questionnaires. All patients who were positive on any questionnaire were invited for a rheumatological assessment. Receiver operating characteristic (ROC) curves were used to compare the sensitivity, specificity and area under the curve of the three questionnaires according to CASPAR criteria. In total, 938 patients with psoriasis were invited to participate and 657 (70%) patients returned the questionnaires. One or more questionnaires were positive in 314 patients (48%) and 195 (62%) of these patients attended for assessment. Of these, 47 patients (24%) were diagnosed with PsA according to the CASPAR criteria. The proportion of patients with PsA increased with the number of positive questionnaires (one questionnaire, 19·1%; two, 34·0%; three, 46·8%). Sensitivities and specificities for the three questionnaires, and areas under the ROC curve were, respectively: Psoriatic Arthritis Screening Evaluation (PASE), 74·5%, 38·5%, 0·594; Psoriasis Epidemiology Screening Tool (PEST), 76·6%, 37·2%, 0·610; Toronto Psoriatic Arthritis Screen (ToPAS), 76·6%, 29·7%, 0·554. The majority of patients with a false positive response had degenerative or osteoarthritis. Although the PEST and ToPAS questionnaires performed slightly better than the PASE questionnaire at identifying PsA, there is little difference between these instruments. These screening tools identify many cases of musculoskeletal disease other than PsA.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052248807

Download citation: RISBibTeXText

PMID: 23311587

DOI: 10.1111/bjd.12190


Related references

Comparison of four validated psoriatic arthritis screening tools in diagnosing psoriatic arthritis in patients with psoriasis (COMPAQ Study). British Journal of Dermatology 176(3): 765-770, 2017

Clinical features of psoriatic arthritis in Korean patients with psoriasis: a cross-sectional observational study of 196 patients with psoriasis using psoriatic arthritis screening questionnaires. Rheumatology International 36(2): 207-212, 2016

Assessment of two screening tools to identify psoriatic arthritis in patients with psoriasis. Journal of the European Academy of Dermatology and Venereology 32(9): 1530-1534, 2018

A validation study of the Simple Psoriatic Arthritis Screening (SiPAS) questionnaire to screen psoriasis patients for psoriatic arthritis. Clinical and Experimental Rheumatology 36(1): 127-135, 2017

Comparative performance of psoriatic arthritis screening tools in patients with psoriasis in European/North American dermatology clinics. Journal of the American Academy of Dermatology 71(4): 649-655, 2014

Screening for Psoriatic Arthritis in Korean Psoriasis Patients Using the Psoriatic Arthritis Screening Evaluation Questionnaire. Annals of Dermatology 27(3): 265-268, 2015

THU0445Validation of The Contest Questionnaires To Screen for Psoriatic Arthritis in Primary Care Psoriasis Patients. Annals of the Rheumatic Diseases 75(Suppl 2): 352.2-352, 2016

Development and pilot-testing of a new tool to screen psoriasis patients for the presence of psoriatic arthritis: the Simple Psoriatic Arthritis Screening (SiPAS) questionnaire. Journal of the European Academy of Dermatology and Venereology 31(3): E167-E169, 2017

THU0451Comparing Four Screening Tools for Psoriatic Arthritis among Subjects Diagnosed with Psoriasis. Annals of the Rheumatic Diseases 75(Suppl 2): 355.1-355, 2016

Screening psoriatic arthritis tools: analysis of the Early Arthritis for Psoriatic Patients questionnaire. Rheumatology 54(1): 200-202, 2015

Long-term study of infliximab in Japanese patients with plaque psoriasis, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma. Journal of Dermatology 38(4): 321-334, 2011

Developing the Thai Siriraj Psoriatic Arthritis Screening Tool and validating the Thai Psoriasis Epidemiology Screening Tool and the Early Arthritis for Psoriatic Patients questionnaire. Rheumatology International 36(10): 1459-1468, 2016

Baseline relationships between psoriasis and psoriatic arthritis: analysis of 221 patients with active psoriatic arthritis. Department of Veterans Affairs Cooperative Study Group on Seronegative Spondyloarthropathies. Journal of Rheumatology 26(8): 1752-1756, 1999

AB0741Detection of Psoriatic Arthritis in Patients with Psoriasis in Daily Routine Care Using Questionnaires for Diagnosis of Psoriatic Arthritis and Fluorescence-Optical Imaging Technique: Diagnostic Value for Detection of Subclinical Signs of Musculoskeletal Inflammation in Psoriasis?. Annals of the Rheumatic Diseases 75(Suppl 2): 1158.1-1158, 2016

Limitations in screening instruments for psoriatic arthritis: a comparison of instruments in patients with psoriasis. Journal of Rheumatology 40(3): 287-293, 2013