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Constituents of cultivated Agaricus blazei

Constituents of cultivated Agaricus blazei

Journal of Natural Medicines 65(2): 307-312

ISSN/ISBN: 1340-3443

PMID: 21240679

DOI: 10.1007/s11418-010-0495-5

Two phenylhexane derivatives (1, 2), benzoylergostane (3), N-benzoyl-L-leucine methyl ester (4), two known ergostanes, and highly degraded incisterol were isolated from fruit bodies of Agaricus blazei. Compound 3 exhibited strong cytotoxicity toward HepG2 cells (IC(50) = 6.0 ± 0.33 μM).

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Accession: 052309262

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