+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Contrast enhancement in multidetector-row computed tomography (MDCT) of the abdomen: intraindividual comparison of contrast media containing 300 mg versus 370 mg iodine per ml



Contrast enhancement in multidetector-row computed tomography (MDCT) of the abdomen: intraindividual comparison of contrast media containing 300 mg versus 370 mg iodine per ml



European Radiology 18(6): 1199-1205



The purpose of this study was to intraindividually evaluate the difference in intraluminal vessel and parenchyma contrast enhancement of two different iodine concentrations in multidetector-row computed tomography (MDCT) of the abdomen. Eighty-three patients underwent baseline and follow-up MDCT-scanning (Somatom Sensation 16; Siemens, Forchheim, Germany) of the abdomen using contrast media containing 370 mg iodine/ml (protocol A; Ultravist 370, Bayer Schering Pharma, Berlin, Germany) and 300 mg iodine/ml (protocol B; Ultravist 300). The total iodine load (37 g iodine) and the iodine delivery rate (1.29 g iodine/s) were identical for both protocols. Contrast enhancement in the portal venous phase was measured in the abdominal aorta, inferior vena cava, portal vein, liver, spleen, pancreas and kidney. Mean attenuation values were compared using paired t-test. Intraindividual comparison revealed no statistically significant differences of the mean attenuation values between protocols A and B for all anatomic sites: abdominal aorta, inferior vena cava, portal vein, liver, spleen, pancreas and kidney (all P > 0.05). Given an injection protocol with constant total iodine load and constant iodine delivery rate, the iodine concentration of contrast media does not significantly influence abdominal contrast enhancement in the portal venous phase.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052325478

Download citation: RISBibTeXText

PMID: 18228023

DOI: 10.1007/s00330-008-0861-9


Related references

Contrast enhancement in chest multidetector computed tomography: intraindividual comparison of 300 mg/ml versus 400 mg/ml iodinated contrast medium. Academic Radiology 16(2): 144-149, 2009

Multidetector computed tomography (MDCT) evaluation of myocardial viability: intraindividual comparison of monomeric vs. dimeric contrast media in a rabbit model. European Radiology 19(2): 290-297, 2008

Multidetector helical computed tomography of the liver: comparison of hepatic enhancement using two different contrast media strategies. Academic Radiology 11(3): 267-271, 2004

High-concentration contrast media in multiphasic abdominal multidetector-row computed tomography: effect of increased iodine flow rate on parenchymal and vascular enhancement. Journal of Computer Assisted Tomography 29(5): 582-587, 2005

Multidetector computed tomography enteroclysis (MDCT-E) with neutral enteral and IV contrast enhancement in tumor detection. European Radiology 15(6): 1178-1183, 2005

Influence of osmolarity of contrast medium and saline flush on computed tomography angiography: comparison of monomeric and dimeric iodinated contrast media with different iodine concentrations at an identical iodine delivery rate. European Journal of Radiology 76(1): 135-139, 2011

Comparison of 2 different protocols for ingestion of low-attenuating oral contrast agent for multidetector computed tomography of the abdomen. Journal of Computer Assisted Tomography 31(2): 218-222, 2007

Systemic and local reactions in leg phlebography with special reference to iodine-containing contrast media. Randomized, prospective, intraindividual double-blind study using iodine-containing contrast media of different osmolarity and iodine concentration. I. Der Radiologe 24(1): 46-50, 1984

Preoperative detection of hepatic metastases from colorectal cancer: Prospective comparison of contrast-enhanced ultrasound and multidetector-row computed tomography (MDCT). Diagnostic and Interventional Imaging 97(9): 851-855, 2017

Different intravenous contrast media concentrations do not affect clinical assessment of 18F-fluorodeoxyglucose positron emission tomography/computed tomography scans in an intraindividual comparison. Investigative Radiology 47(9): 497-502, 2013

Enhancement with water-soluble contrast media in computed tomography of the brain and abdomen. Survey and present state. Acta Radiologica. Supplementum 366: 72-75, 1983

Hepatic enhancement in multiphasic contrast-enhanced MDCT: comparison of high- and low-iodine-concentration contrast medium in same patients with chronic liver disease. Ajr. American Journal of Roentgenology 183(1): 157-162, 2004

64-Slice multidetector row CT angiography of the abdomen: comparison of low versus high concentration iodinated contrast media in a porcine model. British Journal of Radiology 84(999): 221-228, 2011

Catheter insertion for intravenous (IV) contrast infusion in multidetector-row computed tomography (MDCT): defining how catheter caliber selection affects procedure of catheter insertion, IV contrast infusion rate, complication rate, and MDCT image quality. Journal of Computer Assisted Tomography 38(2): 281-284, 2014

Effect of contrast media formulation on computed tomography angiographic contrast enhancement. Veterinary Radiology & Ultrasound 49(3): 233-237, 2008