Cost-effectiveness analysis of preventive methods for occlusal surface according to caries risk: results of a controlled clinical trial

Tagliaferro, E.Pereira.da.Silva.; Marinho, D.Savignon.; Pereira,; Pardi, V.; Ambrosano, Gáucia.Maria.Bovi.; Meneghim,; Pereira, A.Carlos.

Cadernos de Saude Publica 29 Suppl. 1: S121-S130


ISSN/ISBN: 0102-311X
PMID: 25402241
DOI: 10.1590/0102-311x00021613
Accession: 052369590

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This study presents the results of a cost-effectiveness analysis in a controlled clinical trial on the effectiveness of a modified glass ionomer resin sealant ( Vitremer, 3M ESPE) and the application of fluoride varnish (Duraphat, Colgate) on occlusal surfaces of first permanent molars in children 6-8 years of age (N = 268), according to caries risk (high versus low). Children were examined semiannually by the same calibrated dentist for 24 months after allocation in six groups: high and low risk controls (oral health education every three months); high and low risk with varnish (oral health education every three months + varnish biannually); and high and low risk with sealant (oral health education every three months + a single application of sealant). Economic analysis showed that sealing permanent first molars of high-risk schoolchildren showed a C/E ratio of US$ 119.80 per saved occlusal surface and an incremental C/E ratio of US$ 108.36 per additional saved occlusal surface. The study concluded that sealing permanent first molars of high-risk schoolchildren was the most cost-effective intervention.