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Crohn's disease and the SAPHO syndrome during treatment with infliximab: a case report and review of literature

Van Den Eynde, M.; Lecluyse, K.; Chioccioli, C.; Brouckaert, M.; Caussin, E.; Lammens, P.

Gastroenterologie Clinique et Biologique 31(6-7): 607-610

2007


ISSN/ISBN: 0399-8320
PMID: 17646788
Accession: 052388125

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We report the case of a 40 year-old Turkish woman with severe ileal Crohn's disease associated with palmoplantar pustulosis and aseptic spondylitis, also known as the SAPHO syndrome. However, in the present case, the syndrome developed three months after starting infliximab (Remicade) therapy, which is generally used to treat the SAPHO syndrome. This case-report discusses the unclear relationship between Crohn's disease, the appearance of a SAPHO syndrome and treatment with infliximab.

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