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Crohn's disease complicated by primary gastrointestinal Hodgkin's lymphoma presenting with small bowel perforation



Crohn's disease complicated by primary gastrointestinal Hodgkin's lymphoma presenting with small bowel perforation



Journal of Gastrointestinal and Liver Diseases 18(3): 359-361



An increased incidence of non-Hodgkin's lymphoma has been reported in patients with inflammatory bowel disease, particularly in those receiving immunosuppressive therapy. Rare cases of Hodgkin;s lymphoma have been reported in a setting of inflammatory bowel disease. The mechanism underlying the apparent association is unclear, but alterations in immune surveillance could play a role. In this report we describe the clinicopathological features of primary gastrointestinal Hodgkin's lymphoma diagnosed in a patient with Crohn's ileocolitis who had been receiving therapy with immunomodulator and biologic therapies.

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Accession: 052388141

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PMID: 19795032


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