Cyclization reactions involving palladium-catalyzed carbene insertion into aryl halides
Kudirka, R.; Van Vranken, D.L.
Journal of Organic Chemistry 73(9): 3585-3588
2008
ISSN/ISBN: 0022-3263
PMID: 18370420
DOI: 10.1021/jo800109d
Accession: 052423175
Palladium is shown to catalyze the insertion of trimethylsilylmethylene into aryl halides, leading to benzylpalladium intermediates that cyclize to give indenylsilanes through carbopalladation of pendant alkenes or allenes. Allylsilanes generated through these processes are susceptible to protodesilylation in situ.
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