+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Cytotoxic activity of kenaf (Hibiscus cannabinus L.) seed extract and oil against human cancer cell lines



Cytotoxic activity of kenaf (Hibiscus cannabinus L.) seed extract and oil against human cancer cell lines



Asian Pacific Journal of Tropical Biomedicine 4(Suppl 1): S510



To examine the cytotoxic properties of both the kenaf (Hibiscus cannabinus L.) seed extract and kenaf seed oil on human cervical cancer, human breast cancer, human colon cancer and human lung cancer cell lines. The in vitro cytotoxic activity of the kenaf (Hibiscus cannabinus L.) seed extract and kenaf seed oil on human cancer cell lines was evaluated by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and sulforhodamine B assays. Cell morphological changes were observed by using an inverted light microscope. The kenaf seed extract (KSE) exhibited a lower IC50 than kenaf seed oil (KSO) in all of the cancer cell lines. Morphological alterations in the cell lines after KSE and KSO treatment were observed. KSE and KSO possessed effective cytotoxic activities against all the cell lines been selected. KSE and KSO could be potential sources of natural anti-cancer agents. Further investigations on using kenaf seeds for anti-proliferative properties are warranted.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052433304

Download citation: RISBibTeXText

PMID: 25183141

DOI: 10.12980/apjtb.4.2014c1090


Related references

Aspects of plant protection in kenaf Hibiscus cannabinus crops in Germany Aspekte des Pflanzenschutzes beim Anbau von Kenaf Hibiscus cannabinus in Deutschland. Mitteilungen aus der Biologischen Bundesanstalt fuer Land- und Forstwirtschaft Berlin-Dahlem 310: 171-177, 1995

Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon Dioxide Fluid Extraction towards Human Colorectal Cancer (HT29) Cell Lines. Evidence-BasedComplementaryandAlternativeMedicine2013:549705, 2013

Dietary supplementation of defatted kenaf (Hibiscus cannabinus L.) seed meal and its phenolics-saponins rich extract effectively attenuates diet-induced hypercholesterolemia in rats. Food and Function 9(2): 925-936, 2018

Defatted Kenaf ( Hibiscus cannabinus L.) Seed Meal and Its Phenolic-Saponin-Rich Extract Protect Hypercholesterolemic Rats against Oxidative Stress and Systemic Inflammation via Transcriptional Modulation of Hepatic Antioxidant Genes. Oxidative Medicine and Cellular Longevity 2018: 6742571, 2018

Chemical composition of kenaf (Hibiscus cannabinus L.) seed oil. Nippon Nogeikagaku Kaishi 75(12): 1291-1295, 2001

Chemical Composition of Kenaf(Hibiscus cannabinus L.) Seed Oil. Journal of the Agricultural Chemical Society of Japan 75(12): 1291-1295, 2001

Chemical composition of kenaf (Hibiscus cannabinus L.) seed oil. Industrial Crops and Products 4(3): 157-165, 1995

Effect of three row spacings on kenaf (Hibiscus cannabinus) for seed production. Agrotecnia de Cuba 14(1): 63-69, 1982

The cultivation of kenaf hibiscus cannabinus for fiber paper pulp and seed. South Africa Department of Agriculture and Fisheries Technical Communication (186): I-IV, 1-16, 1983

Influence of the inlet air temperature on the microencapsulation of kenaf ( Hibiscus cannabinus L.) seed oil. European Journal of Lipid Science and Technology 115(11): 1309-1318, 2013

Effect of 5 seed spacings on fibre yield of kenaf (Hibiscus cannabinus). Agrotecnia de Cuba 20(2): 1-10, 1988

A cytological study on microsporogenesis of cytoplasmic male sterile lines in kenaf (Hibiscus cannabinus L.). Acta Agronomica Sinica 33(6): 999-1003, 2007

Production of seed of kenaf (Hibiscus cannabinus) in regions where it is grown as a fibre crop.. Selek. Semenovod, 19: 5, 58-9, 1952

The experimental culture of kenaf, Hibiscus cannabinus L., for fiber and seed in South Florida. Turrialba, 2: 3, 99-105. bibl. 34, 1952

Comparative study of crude and refined kenaf ( Hibiscus cannabinus L.) seed oil during accelerated storage. Food Science and Biotechnology 26(1): 63-69, 2017