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List of PDF Full Texts available from EurekaMag Chapter 52504

Chapter 52504 contains a list of PDF Full Texts available from EurekaMag.





Design and optimization of SPR-based binding assay for evaluation and screening of MITF-E-box binding inhibitor
, Molecular Biotechnology 56(3): 265-273 (2014)

Design and optimization of a beam shaping assembly for BNCT based on D-T neutron generator and dose evaluation using a simulated head phantom
, Applied Radiation and Isotopes 70(12): 2755-2762 (2012)

Design and optimization of a chemometric-assisted spectrophotometric determination of telmisartan and hydrochlorothiazide in pharmaceutical dosage form
, Journal of Young Pharmacists 2(1): 85-89 (2010)

Design and optimization of a chromatographic purification process for Streptococcus pneumoniae serotype 23F capsular polysaccharide by a Design of Experiments approach
, Journal of Chromatography. a 1348: 137-149 (2014)

Design and optimization of a diode-pumped fiber-coupled yb:er glass waveguide laser
, Applied Optics 39(33): 6165-6173 (2000)

Design and optimization of a double-enzyme glucose assay in microfluidic lab-on-a-chip
, Biomicrofluidics 3(4): 44103 (2009)

Design and optimization of a high-efficiency array generator in the mid-IR with binary subwavelength grooves
, Applied Optics 50(5): 701-709 (2011)

Design and optimization of a high-speed, high-sensitivity, spinning disk confocal microscopy system
, Journal of Biomedical Optics 13(5): 054058 (2008)

Design and optimization of a light-emitting diode projection micro-stereolithography three-dimensional manufacturing system
, Review of Scientific Instruments 83(12): 125001 (2012)

Design and optimization of a modal- independent linear ultrasonic motor
, IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 61(3): 535-546 (2014)

Design and optimization of a near-field scanning optical microscope for imaging biological samples in liquid
, Applied Optics 37(16): 3574-3581 (1998)

Design and optimization of a new self-nanoemulsifying drug delivery system
, Journal of Colloid and Interface Science 330(2): 443-448 (2009)

Design and optimization of a novel method for extraction of genistein
, Indian Journal of Pharmaceutical Sciences 73(2): 184-192 (2011)

Design and optimization of a novel reverse transcription linear-after-the-exponential PCR for the detection of foot-and-mouth disease virus
, Journal of Applied Microbiology 109(1): 180-189 (2010)

Design and optimization of a novel silicon-on-insulator wavelength diplexer
, Optics Express 22(18): 21521 (2014)

Design and optimization of a novel surface plasmon resonance biosensor based on Otto configuration
, Optics Express 17(26): 23511-23521 (2009)

Design and optimization of a parallel spectrometer for ultra-fast X-ray science
, Optics Express 22(10): 12583-12602 (2014)

Design and optimization of a phosphopeptide anchor for specific immobilization of a capture protein on zirconium phosphonate modified supports
, Langmuir 30(46): 13949-13955 (2014 )

Design and optimization of a reflection-based fiber-optic tweezers
, Optics Express 16(22): 17647-17653 (2008)

Design and optimization of a semicontinuous hot-cold extraction of polyphenols from grape pomace
, Journal of Agricultural and Food Chemistry 60(22): 5571-5582 (2012)

Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors
, Bioorganic and Medicinal Chemistry Letters 20(5): 1524-1527 (2010)

Design and optimization of a stomach-specific drug delivery system of repaglinide: application of simplex lattice design
, Pharmaceutical Development and Technology 17(1): 55-65 (2012)

Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension
, Bioorganic and Medicinal Chemistry Letters 20(7): 2204-2209 (2010)

Design and optimization of a total vaporization technique coupled to solid-phase microextraction
, Analytical Chemistry 86(22): 11319-11325 (2014)

Design and optimization of an achromatic photonic crystal bend
, Optics Express 11(12): 1378-1384 (2003)

Design and optimization of an adaptive optics system for a high-average-power multi-slab laser (HiLASE)
, Applied Optics 53(15): 3255-3261 (2014)

Design and optimization of an irradiance profile-shaping system with a genetic algorithm method
, Applied Optics 37(22): 5216-5221 (1998)

Design and optimization of an ultra wideband and compact microwave antenna for radiometric monitoring of brain temperature
, IEEE Transactions on Bio-Medical Engineering 61(7): 2154-2160 (2014)

Design and optimization of aniline-substituted tetrahydroquinoline C5a receptor antagonists
, Bioorganic and Medicinal Chemistry Letters 18(14): 3852-3855 (2008)

Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists
, Journal of Medicinal Chemistry 54(1): 233-247 (2011)

Design and optimization of beta-cell temperature sensor based on ⁶³Ni-Si
, Applied Radiation and Isotopes 86: 46-51 (2014)

Design and optimization of bilayered tablet of Hydrochlorothiazide using the Quality-by-Design approach
, International Journal of Pharmaceutical Investigation 4(2): 93-101 (2014)

Design and optimization of broadband and polarization-insensitive dual-core photonic crystal fiber coupler
, Applied Optics 50(14): 2016-2023 (2011)

Design and optimization of broadband tapered optical fibers with a nanofiber waist
, Optics Express 18(22): 22677-22685 (2010)

Design and optimization of broadband wide-angle antireflection structures for binary diffractive optics
, Optics Letters 35(7): 907-909 (2010)

Design and optimization of coin-shaped microreactor chips for PET radiopharmaceutical synthesis
, Journal of Nuclear Medicine 51(2): 282-287 (2010)

Design and optimization of colon-targeted system of theophylline for chronotherapy of nocturnal asthma
, Journal of Pharmaceutical Sciences 100(5): 1760-1772 (2011)

Design and optimization of color lookup tables on a simplex topology
, IEEE Transactions on Image Processing 21(4): 1981-1996 (2012)

Design and optimization of diclofenac sodium controlled release solid dispersions by response surface methodology
, Indian Journal of Pharmaceutical Sciences 70(1): 22-30 (2008)

Design and optimization of drugs used to treat copper deficiency
, Expert Opinion on Drug Discovery 8(10): 1253-1263 (2013)

Design and optimization of ethanol production from bagasse pith hydrolysate by a thermotolerant yeast Kluyveromyces sp. IIPE453 using response surface methodology
, Springerplus 2(1): 159 (2013)

Design and optimization of fermentation medium for enhanced bacteriocin production by probiotic bacterium Enterococcus faecium MC13
, Preparative Biochemistry and Biotechnology 41(1): 40-52 (2011)

Design and optimization of fiber optical parametric oscillators for femtosecond pulse generation
, Optics Express 18(16): 17294-17305 (2010)

Design and optimization of floating drug delivery system of acyclovir
, Indian Journal of Pharmaceutical Sciences 72(5): 599-606 (2010)

Design and optimization of genetically encoded fluorescent biosensors: GTPase biosensors
, Methods in Cell Biology 85: 63-81 (2008)

Design and optimization of highly nonlinear low-dispersion crystal fiber with high birefringence for four-wave mixing
, Applied Optics 49(16): 3208-3214 (2010)

Design and optimization of highly-selective fungal CYP51 inhibitors
, Bioorganic and Medicinal Chemistry Letters 24(15): 3455-3458 (2014 )

Design and optimization of in-plane actuator driven cantilever with high sensitivity sensors
, Journal of Nanoscience and Nanotechnology 10(5): 3236-3240 (2010)

Design and optimization of large area thin-film CdTe detector for radiation therapy imaging applications
, Medical Physics 37(8): 3980-3994 (2010)

Design and optimization of liquid core optical ring resonator for refractive index sensing
, Applied Optics 50(20): 3615-3621 (2011)

Design and optimization of low-loss high-birefringence hollow fiber at terahertz frequency
, Optics Express 19(25): 24967-24979 (2011)

Design and optimization of low-loss wideband antireflection coatings for the visible and infrared regions: a new method
, Applied Optics 24(8): 1156 (1985)

Design and optimization of mechanically down-doped terahertz fiber directional couplers
, Optics Express 22(8): 9486-9497 (2014)

Design and optimization of mefloquine hydrochloride microparticles for bitter taste masking
, Aaps Pharmscitech 9(2): 377-389 (2008)

Design and optimization of microlens array based high resolution beam steering system
, Optics Express 15(8): 4523-4529 (2007)

Design and optimization of multi-class series-parallel linear electromagnetic array artificial muscle
, Bio-Medical Materials and Engineering 24(1): 549-555 (2014)

Design and optimization of new piperidines as renin inhibitors
, Bioorganic and Medicinal Chemistry Letters 20(21): 6286-6290 (2010 )

Design and optimization of non-clogging counter-flow microconcentrator for enriching epidermoid cervical carcinoma cells
, Biomedical Microdevices 13(1): 179-190 (2011)

Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(14): 4561-4566 (2012)

Design and optimization of novel 4-(2-fluorophenoxy)quinoline derivatives bearing a hydrazone moiety as c-Met kinase inhibitors
, European Journal of Medicinal Chemistry 87: 508-518 (2014)

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis
, Journal of Medicinal Chemistry 57(22): 9357-9369 (2014)

Design and optimization of partial Mueller matrix polarimeters
, Applied Optics 49(12): 2326-2333 (2010)

Design and optimization of photo bioreactor for O2 regulation and control by system dynamics and computer simulation
, Bioresource Technology 104: 608-615 (2012)

Design and optimization of photovoltaics recycling infrastructure
, Environmental Science and Technology 44(22): 8678-8683 (2010)

Design and optimization of polyphosphazene functionalized fiber matrices for soft tissue regeneration
, Journal of Biomedical Nanotechnology 8(1): 107-124 (2012)

Design and optimization of porous polymer enzymatic digestors for proteomics
, Journal of Separation Science 32(15-16): 2642-2652 (2009)

Design and optimization of potent and orally bioavailable tetrahydronaphthalene Raf inhibitors
, Journal of Medicinal Chemistry 54(6): 1836-1846 (2011)

Design and optimization of potent, selective antagonists of Oxytocin
, Bioorganic and Medicinal Chemistry Letters 18(15): 4278-4281 (2008)

Design and optimization of printed spiral coils for efficient transcutaneous inductive power transmission
, IEEE Transactions on Biomedical Circuits and Systems 1(3): 193-202 (2007)

Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687)
, Journal of Medicinal Chemistry 55(23): 10610-10629 (2012)

Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists
, Bioorganic and Medicinal Chemistry Letters 22(9): 3157-3162 (2012)

Design and optimization of reaction chamber and detection system in dynamic labs-on-chip for proteins detection
, IEEE Transactions on Bio-Medical Engineering 60(8): 2161-2166 (2013)

Design and optimization of renin inhibitors: Orally bioavailable alkyl amines
, Bioorganic and Medicinal Chemistry Letters 19(13): 3541-3545 (2009)

Design and optimization of resonance-based efficient wireless power delivery systems for biomedical implants
, IEEE Transactions on Biomedical Circuits and Systems 5(1): 48-63 (2011)

Design and optimization of reverse-transcription quantitative PCR experiments
, Clinical Chemistry 55(10): 1816-1823 (2009)

Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases
, Journal of Medicinal Chemistry 56(5): 1799-1810 (2013)

Design and optimization of self-nanoemulsifying delivery system to enhance quercetin hepatoprotective activity in paracetamol-induced hepatotoxicity
, Journal of Pharmaceutical Sciences 103(2): 602-612 (2014)

Design and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for enhanced dissolution of gemfibrozil
, International Journal of Pharmaceutics 431(1-2): 161-175 (2012)

Design and optimization of short DNA sequences that can be used as 5' fusion partners for high-level expression of heterologous genes in Escherichia coli
, Applied and Environmental Microbiology 79(21): 6655-6664 (2013)

Design and optimization of some collagen-minocycline based hydrogels potentially applicable for the treatment of cutaneous wound infections
, Die Pharmazie 66(11): 853-861 (2011)

Design and optimization of space-variant photonic crystal filters
, Applied Optics 46(23): 5755-5761 (2007)

Design and optimization of surfactant-based nanovesicles for ocular delivery of Clotrimazole
, Journal of Liposome Research 23(3): 203-210 (2013)

Design and optimization of sustained-release divalproex sodium tablets with response surface methodology
, Aaps Pharmscitech 14(1): 245-253 (2013)

Design and optimization of the calibration procedure for a miniaturized Fourier transform spectrometer
, Applied Spectroscopy 65(6): 627-633 (2011)

Design and optimization of the sine condition test for measuring misaligned optical systems
, Applied Optics 52(29): 7099-7108 (2013)

Design and optimization of ultrasound assisted extraction of curcumin as an effective alternative for conventional solid liquid extraction of natural products
, Natural Product Communications 4(1): 95-100 (2009)

Design and optimization of voice coil actuator for six degree of freedom active vibration isolation system using Halbach magnet array
, Review of Scientific Instruments 83(10): 105117 (2012)

Design and optimization of waveguide sensitivity in slot microring sensors
, Journal of the Optical Society of America. A Optics Image Science and Vision 28(4): 596-603 (2011)

Design and optimization of wireless power and data transmission for visual prosthesis
, Zhongguo Yi Liao Qi Xie Za Zhi 37(6): 427-431 (2013)

Design and optimization technique for three-mirror telescopes
, Applied Optics 19(21): 3640-3645 (1980)

Design and outcomes of a Mothers In Motion behavioral intervention pilot study
, Journal of Nutrition Education and Behavior 42(3 Suppl): S11 (2010)

Design and outcomes of an acoustic data visualization seminar
, Journal of the Acoustical Society of America 135(1): El41 (2014)

Design and outcomes of computer-based cognitive prosthetics for brain injury: a field study of three subjects
, Neurorehabilitation 4(3): 174-186 (1994)

Design and outline of the Healthy Pregnancy 4 All study
, Bmc Pregnancy and Childbirth 14: 253 (2014)

Design and parallel fabrication of wire-grid polarization arrays for polarization-resolved imaging at 1.55 microm
, Applied Optics 47(20): 3555-3560 (2008 )

Design and parallel synthesis of new bicyclic small molecules for targeting the melanocortin receptors
, Advances in Experimental Medicine and Biology 611: 187-188 (2009)

Design and parameterization of a stochastic cellular automaton describing a chemical reaction
, Journal of Computational Chemistry 32(9): 1952-1961 (2011)

Design and participant characteristics of a randomized-controlled trial of telemedicine for smoking cessation among rural smokers
, Contemporary Clinical Trials 38(2): 173-181 (2014)

Design and patient characteristics of ESHOL study, a Catalonian prospective randomized study
, Journal of Nephrology 24(2): 196-202 (2011)

Design and performance analysis of fiber-optic infinite-impulse response filters
, Applied Optics 31(23): 4700-4711 (1992)

Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications
, Physics in Medicine and Biology 58(20): 7209-7226 (2013)

Design and performance evaluation of a broadband three dimensional acoustic intensity measuring system
, Journal of the Acoustical Society of America 127(4): 2338-2346 (2010)

Design and performance evaluation of a coplanar multimodality scanner for rodent imaging
, Physics in Medicine and Biology 54(18): 5427-5441 (2009)

Design and performance evaluation of a dispersion compensation unit using several chirping functions in a tanh apodized FBG and comparison with dispersion compensation fiber
, Applied Optics 53(29): H239 (2014)

Design and performance evaluation of a distributed OFDMA-based MAC protocol for MANETs
, Thescientificworldjournal 2014: 708798 (2014)

Design and performance evaluation of a medium flow sampler for airborne brominated flame retardants (BFRs)
, Journal of Environmental Monitoring 11(4): 858-866 (2009)

Design and performance evaluation of a microfluidic ion-suppression module for anion-exchange chromatography
, Journal of Chromatography. a 1355: 253-260 (2014)

Design and performance evaluation of a minimally invasive telerobotic platform for transurethral surveillance and intervention
, IEEE Transactions on Bio-Medical Engineering 60(4): 918-925 (2013)

Design and performance evaluation of a remote catheter navigation system
, IEEE Transactions on Bio-Medical Engineering 56(7): 1901-1908 (2009)

Design and performance evaluation of a whole-body Ingenuity TF PET-MRI system
, Physics in Medicine and Biology 56(10): 3091-3106 (2011)

Design and performance evaluation of an OpenFlow-based control plane for software-defined elastic optical networks with direct-detection optical OFDM (DDO-OFDM) transmission
, Optics Express 22(1): 30-40 (2014)

Design and performance evaluation of dynamic wavelength scheduled hybrid WDM/TDM PON for distributed computing applications
, Optics Express 17(2): 1023-1032 (2009)

Design and performance evaluation of polyvinyl alcohol/polyimide coated optical fibre grating-based humidity sensors
, Review of Scientific Instruments 84(2): 025002 (2013)

Design and performance evaluation of single-use whole-sterile "plug & play" kits for routine automated production of [(11)C]choline and [(11)C]methionine with radiopharmaceutical quality
, Applied Radiation and Isotopes 68(12): 2298-2301 (2010)

Design and performance from an integrated PET/MRI system for small animals
, Annals of Nuclear Medicine 24(2): 89-98 (2010)

Design and performance of AERHA, a high acceptance high resolution soft x-ray spectrometer
, Review of Scientific Instruments 85(4): 043108 (2014)

Design and performance of Huffman sequences in medical ultrasound coded excitation
, IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 59(4): 630-647 (2012)

Design and performance of a 20-stage digital light beam deflector
, Applied Optics 11(8): 1732-1736 (1972)

Design and performance of a ZnSe tetra-prism for homogeneous substrate heating using a CO2 laser for pulsed laser deposition experiments
, Applied Optics 47(11): 1767-1780 (2008)

Design and performance of a combined secondary ion mass spectrometry-scanning probe microscopy instrument for high sensitivity and high-resolution elemental three-dimensional analysis
, Review of Scientific Instruments 83(6): 063702 (2012)

Design and performance of a compact Li+ ion attachment mass spectrometry system with an atmospheric sampling device
, Journal of the American Society for Mass Spectrometry 23(3): 547-552 (2012)

Design and performance of a compact and stationary microSPECT system
, Medical Physics 40(11): 112501 (2013)

Design and performance of a curved-crystal x-ray emission spectrometer
, Review of Scientific Instruments 78(5): 053101 (2007)

Design and performance of a desktop time-of-flight mass spectrometer for analyzing metal ions
, European Journal of Mass Spectrometry 18(4): 349-360 (2012)

Design and performance of a direct-reading, multichannel spectrometer for the determination of chlorinated purgeable organic compounds by flame infrared-emission spectrometry
, Talanta 38(6): 589-602 (1991)

Design and performance of a few-kilohertz-linewidth dye laserstabilized by reflection in an optical resonator
, Optics Letters 13(10): 823-825 (1988)

Design and performance of a field exposure system for evaluation of the ecological effects of SO2 on native grassland
, Environmental Monitoring and Assessment 1(3): 213-228 (1982)

Design and performance of a flow-through polarization-modulation infrared reflection-absorption spectroscopy cell for time-resolved simultaneous surface and liquid phase detection under concentration and temperature perturbations
, Review of Scientific Instruments 80(9): 094101 (2009)

Design and performance of a high resolution electrospray ion source for a magnetic sector mass spectrometer with a heated capillary inlet
, Journal of the American Society for Mass Spectrometry 6(12): 1256-1261 (1995)

Design and performance of a high spatial resolution, time-of-flight PET detector
, IEEE Transactions on Nuclear Science 61(3): 1092-1098 (2014)

Design and performance of a high-power, synchronized Nd:YAG-dye laser system
, Optics Letters 14(1): 42-44 (1989)

Design and performance of a multicellular Geiger counter for gamma-radiation
, Review of Scientific Instruments 20(4): 233-235 (1949)

Design and performance of a multichannel vestibular prosthesis that restores semicircular canal sensation in rhesus monkey
, IEEE Transactions on Neural Systems and Rehabilitation Engineering 19(5): 588-598 (2011)

Design and performance of a multiprocessor system employing board-to-board free-space optical interconnections: COSINE-1
, Applied Optics 30(17): 2334-2343 (1991)

Design and performance of a multisensor heart failure monitoring algorithm: results from the multisensor monitoring in congestive heart failure (MUSIC) study
, Journal of Cardiac Failure 18(4): 289-295 (2012)

Design and performance of a new VIS-VUV photoluminescence beamline at UVSOR-III
, Journal of Synchrotron Radiation 21(Pt 2): 452-455 (2014)

Design and performance of a new continuous-flow sample-introduction system for flame infrared-emission spectrometry: Applications in process analysis, flow injection analysis, and ion-exchange high-performance liquid chromatography
, Talanta 40(6): 867-878 (1993)

Design and performance of a new induction furnace for heat treatment of superconducting radiofrequency niobium cavities
, Review of Scientific Instruments 83(6): 065105 (2012)

Design and performance of a new line focus geometry for xray laser experiments
, Applied Optics 26(9): 1584-1588 (1987)

Design and performance of a practical variable-temperature scanning tunneling potentiometry system
, Review of Scientific Instruments 79(7): 073904 (2008)

Design and performance of a programmable spatial CCD filter
, Applied Optics 31(11): 1762-1768 (1992)

Design and performance of a pulse transformer based on Fe-based nanocrystalline core
, Review of Scientific Instruments 82(8): 084703 (2011)

Design and performance of a punch mechanism based pellet injector for alternative injection in the large helical device
, Review of Scientific Instruments 82(2): 023505 (2011)

Design and performance of a refractive optical system that converts a Gaussian to a flattop beam
, Applied Optics 39(30): 5488-5499 (2000)

Design and performance of a respiratory amplitude gating device for PET/CT imaging
, Medical Physics 37(4): 1408-1412 (2010)

Design and performance of a scanning ptychography microscope
, Review of Scientific Instruments 85(3): 033707 (2014)

Design and performance of a small-animal imaging system using synthetic collimation
, Physics in Medicine and Biology 58(10): 3397-3412 (2013)

Design and performance of a stable linear retarder
, Applied Optics 36(25): 6458-6465 (1997)

Design and performance of a sub-nanoradian resolution autocollimating optical lever
, Review of Scientific Instruments 78(3): 035105 (2007)

Design and performance of a system for blood collection of rats under whole-body inhalation exposure
, Journal of Toxicological Sciences 34(2): 221-226 (2009)

Design and performance of a throughput-matched, zero-geometric-loss, modified three objective multipass matrix system for FTIR spectrometry
, Applied Optics 46(32): 7872-7883 (2007)

Design and performance of a turbot (Scophthalmus maximus) oligo-microarray based on ESTs from immune tissues
, Marine Biotechnology 12(4): 452-465 (2010)

Design and performance of a versatile curved-crystal spectrometer for high-resolution spectroscopy in the tender x-ray range
, Review of Scientific Instruments 83(3): 033113 (2012)

Design and performance of an absolute gas refractometer based on a synthetic pseudo-wavelength method
, Applied Optics 52(16): 3671-3679 (2013)

Design and performance of an automated radionuclide separator: its application on the determination of ⁹⁹Tc in groundwater
, Applied Radiation and Isotopes 81: 57-61 (2013)

Design and performance of an evolved gas analysis ion attachment mass spectrometer
, Rapid Communications in Mass Spectrometry 24(17): 2625-2630 (2010)

Design and performance of an in-line surface-induced dissociation device in a four-sector mass spectrometer
, Journal of the American Society for Mass Spectrometry 6(4): 257-263 (1995)

Design and performance of an instrument for soft landing of biomolecular ions on surfaces
, Analytical Chemistry 79(17): 6566-6574 (2007)

Design and performance of an optically accessible, low-volume, mechanobioreactor for long-term study of living constructs
, Tissue Engineering. Part C Methods 17(7): 775-788 (2011)

Design and performance of an ultra-high vacuum scanning tunneling microscope operating at dilution refrigerator temperatures and high magnetic fields
, Review of Scientific Instruments 84(10): 103903 (2013)

Design and performance of an ultra-high-vacuum-compatible artificial channel-cut monochromator
, Journal of Synchrotron Radiation 15(Pt 1): 12-18 (2008)

Design and performance of clinical trials in head and neck cancer
, Current Opinion in Oncology 22(3): 184-185 (2010)

Design and performance of cryogenic, scanning Fabry-Perot interferometers for the Long-Wavelength Spectrometer on the Infrared Space Observatory
, Applied Optics 34(1): 92-107 (1995)

Design and performance of diffractive optics for custom laser resonators
, Applied Optics 34(14): 2498-2509 (1995)

Design and performance of hybrid constructed wetland systems for high-content wastewater treatment in the cold climate of Hokkaido, northern Japan
, Water Science and Technology 68(7): 1468-1476 (2013)

Design and performance of miniature cyclones for respirable aerosol sampling
, Environmental Science and Technology 17(7): 418-424 (1983)

Design and performance of personal cooling garments based on three-layer laminates
, Medical and Biological Engineering and Computing 46(8): 825-832 (2008)

Design and performance of reflective terahertz air-biased-coherent-detection for time-domain spectroscopy
, Optics Express 18(3): 2872-2883 (2010)

Design and performance of spinal fixation pedicle screw system
, Proceedings of the Institution of Mechanical Engineers. Part H Journal of Engineering in Medicine 226(1): 33-40 (2012)

Design and performance of tapered cubic anvil used for achieving higher pressure and larger sample cell
, Review of Scientific Instruments 84(7): 073902 (2013)

Design and performance of the CDC real-time reverse transcriptase PCR swine flu panel for detection of 2009 A (H1N1) pandemic influenza virus
, Journal of Clinical Microbiology 49(7): 2614-2619 (2011)

Design and performance of the collective Thomson scattering receiver at ASDEX Upgrade
, Review of Scientific Instruments 83(1): 013507 (2012)

Design and performance optimization of fiber optic adaptive filters
, Applied Optics 30(14): 1826-1838 (1991)

Design and performance testing of an axial-flow ventricular assist device developed at the Fu Wai Hospital in Beijing
, International Journal of Artificial Organs 31(11): 983-987 (2008)

Design and performance testing of an ultrasonic linear motor with dual piezoelectric actuators
, IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 59(5): 1033-1042 (2012)

Design and pharmaceutical evaluation of a nano-enabled crosslinked multipolymeric scaffold for prolonged intracranial release of Zidovudine
, Journal of Pharmacy and Pharmaceutical Sciences 16(3): 470-485 (2013)

Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid
, Epilepsy and Behavior 22(3): 461-468 (2011)

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor
, British Journal of Pharmacology 170(1): 89-100 (2013)

Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus
, Biochemistry 48(50): 11872-11882 (2009)

Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel
, Bioorganic and Medicinal Chemistry Letters 21(16): 4857-4859 (2011)

Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor
, Proceedings of the National Academy of Sciences of the United States of America 110(14): 5689-5694 (2013)

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors
, Bioorganic and Medicinal Chemistry 18(2): 496-507 (2010)

Design and photophysical properties of zinc(II) porphyrin-containing dendrons linked to a central artificial special pair
, Chemistry 17(51): 14643-14662 (2011)

Design and photovoltaic characterization of dithieno[3,2-b:2',3'-d]silole copolymers with positioning phenyl groups
, Physical Chemistry Chemical Physics 16(48): 26893-26900 (2014)

Design and physical characterization of a synchronous multivalve aortic valve culture system
, Annals of Biomedical Engineering 38(2): 319-325 (2010)

Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs
, Journal of Controlled Release 180: 71-80 (2014)

Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation
, Drug Design Development and Therapy 7: 59-72 (2013)

Design and physicochemical characterization of poly(amidoamine) nanoparticles and the toxicological evaluation in human endothelial cells: applications to peptide delivery to the brain
, Journal of Biomaterials Science. Polymer Edition 24(8): 957-971 (2013)

Design and physicochemical properties of new fluorescent ligands of protein kinase C isozymes focused on CH/pi interaction
, Bioorganic and Medicinal Chemistry 16(2): 650-657 (2008)

Design and physicochemical stability studies of paediatric oral formulations of sildenafil
, International Journal of Pharmaceutics 460(1-2): 234-239 (2014)

Design and pilot evaluation of an Internet spit tobacco cessation program
, Journal of Dental Hygiene 82(1): 11 (2008)

Design and pilot implementation of an evaluation tool assessing professionalism, communication and collaboration during a unique global health elective
, Medicine Conflict and Survival 30(1): 56-65 (2014)

Design and pilot results of a mobile phone weight-loss application for women starting a meal replacement programme
, Journal of Telemedicine and Telecare 19(3): 166-174 (2013)

Design and piloting of a structured service medication dispensing process
, Atencion Primaria 47(1): 7-14 (2015)

Design and planning of sanatoria
, Monthly Bulletin of the Ministry of Health and the Public Health Laboratory Service 5: 250-258 (1946)

Design and potential application of PEGylated gold nanoparticles with size-dependent permeation through brain microvasculature
, Nanomedicine 7(6): 992-1000 (2011)

Design and power analysis: n and confidence intervals of means
, Psicothema 20(4): 933-938 (2008)

Design and powering of cystic fibrosis clinical trials using rate of FEV(1) decline as an efficacy endpoint
, Journal of Cystic Fibrosis 9(5): 332-338 (2010)

Design and practice of the Clinical Information System for ICU
, Zhongguo Yi Liao Qi Xie Za Zhi 31(5): 348-352 (2007 )

Design and practices for use of automated drilling and sample handling in MARTE while minimizing terrestrial and cross contamination
, Astrobiology 8(5): 947-965 (2008)

Design and pre-clinical development of epitope-based DNA vaccines against B-cell lymphoma
, Current Gene Therapy 11(5): 414-422 (2011)

Design and pre-clinical evaluation of a universal HIV-1 vaccine
, Plos one 2(10): E984 (2007)

Design and pre-clinical profiling of a Plasmodium falciparum MSP-3 derived component for a multi-valent virosomal malaria vaccine
, Malaria Journal 8: 314 (2009)

Design and preclinical development of a recombinant protein and DNA plasmid mixed format vaccine to deliver HIV-derived T-lymphocyte epitopes
, Vaccine 27(50): 7087-7095 (2009)

Design and preclinical evaluation of a 99mTc-labelled diabody of mAb J591 for SPECT imaging of prostate-specific membrane antigen (PSMA)
, Ejnmmi Research 4(1): 13 (2014)

Design and preliminary accuracy studies of an MRI-guided transrectal prostate intervention system
, Medical Image Computing and Computer-Assisted Intervention 10(Pt 2): 59-67 (2007)

Design and preliminary clinical application of a new digitalized navigation template for fixation of the inferior tibiofibular joint
, Nan Fang Yi Ke Da Xue Xue Bao 29(7): 1364-1366 (2009)

Design and preliminary evaluation of the FINGER rehabilitation robot: controlling challenge and quantifying finger individuation during musical computer game play
, Journal of Neuroengineering and Rehabilitation 11: 10 (2014)

Design and preliminary in vivo validation of a robotic laparoscope holder for minimally invasive surgery
, International Journal of Medical Robotics + Computer Assisted Surgery 5(3): 319-326 (2009)

Design and preliminary results of a metropolitan lifestyle intervention program for people with metabolic syndrome in South Korea
, Diabetes Research and Clinical Practice 101(3): 293-302 (2013)

Design and preliminary results of a pilot randomized controlled trial on a 1:1:1 transfusion strategy: the trauma formula-driven versus laboratory-guided study
, Journal of Trauma 71(5 Suppl 1): S418 (2011)

Design and preliminary results of the heart function assessment registry trial in Saudi Arabia (HEARTS) in patients with acute and chronic heart failure
, European Journal of Heart Failure 13(11): 1178-1184 (2011)

Design and preliminary structure-activity relationship of redox-silent semisynthetic tocotrienol analogues as inhibitors for breast cancer proliferation and invasion
, Bioorganic and Medicinal Chemistry 18(2): 755-768 (2010)

Design and preliminary study of custom laser scanning cystoscope for automated bladder surveillance
, Minimally Invasive Therapy and Allied Technologies 21(5): 320-328 (2012)

Design and preliminary testing of a visually guided hearing aid
, Journal of the Acoustical Society of America 133(3): El202-7 (2013)

Design and preliminary testing of an active intramedullary nail
, Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 66(Suppl. 1): S70 (2014)

Design and preliminary validation of a tool for nursing assessment and classification for pediatric patients in primary health care emergency. "VEUPAP"
, Revista de Enfermeria 36(11): 16-25 (2013)

Design and preliminary validation of the verbal skill scale in the dental setting: an anxiety scale for children
, Pediatric Dentistry 35(2): E43 (2013)

Design and preparation of a chiral ligand based on a pseudorotaxane skeleton: application to rhodium-catalyzed enantioselective hydrogenation of enamides
, Journal of the American Chemical Society 129(43): 12930 (2007)

Design and preparation of a core-shell metal-organic framework for selective CO2 capture
, Journal of the American Chemical Society 135(27): 9984-9987 (2013)

Design and preparation of a novel temperature-responsive ionic gel. 3. Valence selective control of transport modes of ions in response to temperature
, Journal of Physical Chemistry. B 112(21): 6585-6593 (2008)

Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid
, Journal of Medicinal Chemistry 55(21): 9009-9024 (2012)

Design and preparation of aza-analogues of benzo[c]phenanthridine framework with cytotoxic and antiplasmodial activities
, European Journal of Medicinal Chemistry 45(7): 2854-2859 (2010)

Design and preparation of bioactive glasses with hierarchical pore networks
, Chemical Communications 2007(21): 2139-2141 (2007)

Design and preparation of co-crystals utilizing the R(4)(2)(8) hydrogen-bonding motif
, Chemistry 16(30): 9047-9055 (2010)

Design and preparation of ethynyl-pyrene modified platinum-acetylide gelators and their application in dispersion of graphene
, Chemical Communications 50(71): 10269-10272 (2014)

Design and preparation of market baskets of European Union commercial baby foods for the assessment of infant exposure to food chemicals and to their effects
, Food Additives and Contaminants. Part A Chemistry Analysis Control Exposure and Risk Assessment 27(10): 1337-1351 (2010)

Design and preparation of materials for advanced electrochemical storage
, Accounts of Chemical Research 46(5): 1226-1238 (2013)

Design and preparation of molybdenum-dinitrogen complexes with ferrocenyldiphosphine and pentamethylcyclopentadienyl moieties as auxiliary ligands
, Chemistry 19(36): 11874 (2013)

Design and preparation of platinum-acetylide organogelators containing ethynyl-pyrene moieties as the main skeleton
, Chemistry 18(50): 16000-16013 (2012)

Design and preparation of polyurethane-collagen/heparin-conjugated polycaprolactone double-layer bionic small-diameter vascular graft and its preliminary animal tests
, Chinese Medical Journal 126(7): 1310-1316 (2013)

Design and preparation of porous polymers
, Chemical Reviews 112(7): 3959-4015 (2012)

Design and preparation of potent, nonpeptidic, bioavailable renin inhibitors
, Journal of Medicinal Chemistry 52(12): 3689-3702 (2009)

Design and preparation of single-chain nanocarriers mimicking disordered proteins for combined delivery of dermal bioactive cargos
, Macromolecular Rapid Communications 34(21): 1681-1686 (2013)

Design and preparation of sterol mimetics as potential antiparasitics
, Bioorganic and Medicinal Chemistry 18(20): 7291-7301 (2010)

Design and primary application of computer-assisted, patient-specific navigational templates in metal-on-metal hip resurfacing arthroplasty
, Journal of Arthroplasty 26(7): 1083-1087 (2011)

Design and probing of efflux functions of EGFP fused ABC membrane transporters in live cells using fluorescence spectroscopy
, Analytical and Bioanalytical Chemistry 400(1): 223-235 (2011)

Design and process evaluation of an informative website tailored to breast cancer survivors' and intimate partners' post-treatment care needs
, Bmc Research Notes 5: 548 (2012)

Design and process of the EMA Cohort Study: the value of antenatal education in childbirth and breastfeeding
, Bmc Nursing 7: 5 (2008)

Design and processing of nanogels as delivery systems for peptides and proteins
, Therapeutic Delivery 5(6): 691-708 (2014)

Design and processing of porous materials for electronic applications
, Philosophical Transactions. Series A Mathematical Physical and Engineering Sciences 364(1838): 175-187 (2006)

Design and production of 3D printed bolus for electron radiation therapy
, Journal of Applied Clinical Medical Physics 15(4): 4831 (2014)

Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide
, Biomacromolecules 12(8): 2957-2965 (2011)

Design and production of bicolour reflecting coatings with Au metal island films
, Optics Express 19(25): 25521 (2011)

Design and production of gentamicin/dextrans microparticles by supercritical assisted atomisation for the treatment of wound bacterial infections
, International Journal of Pharmaceutics 440(2): 188-194 (2013)

Design and production of multimeric antibody fragments, focused on diabodies with enhanced clinical efficacy
, Methods in Molecular Biology 907: 699-712 (2012)

Design and production of nanoparticles formulated from nano-emulsion templates-a review
, Journal of Controlled Release 128(3): 185-199 (2008)

Design and production of retro- and lentiviral vectors for gene expression in hematopoietic cells
, Methods in Molecular Biology 506: 191-205 (2009)

Design and production technology of replicated aspheric objective lenses for optical disk systems
, Applied Optics 24(12): 1853 (1985)

Design and properties of a cryogenic dip-stick scanning tunneling microscope with capacitive coarse approach control
, Review of Scientific Instruments 85(1): 013706 (2014)

Design and properties of dielectric surface plasmon Bragg mirrors
, Optics Express 18(14): 14496-14510 (2010)

Design and properties of functional hybrid organic-inorganic membranes for fuel cells
, Chemical Society Reviews 40(2): 961-1005 (2011)

Design and properties of functional nanotubes from the self-assembly of cyclic peptide templates
, Chemical Society Reviews 41(18): 6023-6041 (2012)

Design and properties of intermediate-sized narrow band-gap conjugated molecules relevant to solution-processed organic solar cells
, Journal of the American Chemical Society 136(15): 5697-5708 (2014)

Design and prospective validation of a dosing instrument for continuous infusion of vancomycin: a within-population approach
, European Journal of Clinical Pharmacology 70(11): 1353-1359 (2014)

Design and prototyping of a chip-based multi-micro-organoid culture system for substance testing, predictive to human (substance) exposure
, Journal of Biotechnology 148(1): 70-75 (2010)

Design and prototyping of a system for ankle spasticity quantification
, Computer Methods in Biomechanics and Biomedical Engineering 15(Suppl. 1): 237-239 (2012)

Design and publication of work on stability constants
, Talanta 21(8): 809-829 (1974)

Design and quality assurance of new dialysis centers
, Saudi Journal of Kidney Diseases and Transplantation 12(3): 413-419 (2001)

Design and quality control of a pharmaceutical formulation containing natural products with antibacterial, antifungal and antioxidant properties
, International Journal of Pharmaceutics 378(1-2): 51-58 (2009)

Design and quality control of short interfering RNAs
, Molekuliarnaia Biologiia 46(6): 827-845 (2012)

Design and quality of ICF-compatible data items for national disability support services
, Disability and Rehabilitation 33(9): 758-769 (2011)

Design and rationale for Home Blood Pressure Telemonitoring and Case Management to Control Hypertension (HyperLink): a cluster randomized trial
, Contemporary Clinical Trials 33(4): 794-803 (2012)

Design and rationale for the PREVAIL study: effect of e-Health individually tailored encouragements to physical exercise on aerobic fitness among adolescents with congenital heart disease--a randomized clinical trial
, American Heart Journal 163(4): 549-556 (2012)

Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial
, American Heart Journal 167(4): 437-444.E5 (2014)

Design and rationale for the non-interventional Global Investigation of Therapeutic DEcisions in Hepatocellular Carcinoma and Of its Treatment with Sorafenib (GIDEON) study
, International Journal of Clinical Practice 64(8): 1034-1041 (2010)

Design and rationale of CURRENT-OASIS 7: a randomized, 2 x 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non-ST-elevation acute coronary syndromes managed with an early invasive strategy
, American Heart Journal 156(6): 1080-1088.E1 (2008)

Design and rationale of FOCUS (PX-171-011): a randomized, open-label, phase 3 study of carfilzomib versus best supportive care regimen in patients with relapsed and refractory multiple myeloma (R/R MM)
, Bmc Cancer 12: 415 (2012)

Design and rationale of Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation: a global registry program on long-term oral antithrombotic treatment in patients with atrial fibrillation
, American Heart Journal 167(3): 329-334 (2014)

Design and rationale of Japanese evaluation between Formula of Azelnidipine and amlodipine add on olmesartan to Get antialbuminuric effect study (J-FLAG) : evaluation of the antialbuminuric effects between calcium channel blocker with sympatholytic action in hypertensive patients with diabetes and albuminuria
, Cardiovascular Drugs and Therapy 25(4): 341-347 (2011)

Design and rationale of a 16-week adjunctive randomized placebo-controlled trial of mitochondrial agents for the treatment of bipolar depression
, Revista Brasileira de Psiquiatria 37(1): 3-12 (2015)

Design and rationale of a comparative effectiveness trial evaluating transcendental meditation against established therapies for PTSD
, Contemporary Clinical Trials 39(1): 50-56 (2014)

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec
, Cardiology in the Young 21(6): 654-664 (2011)

Design and rationale of a randomized controlled trial to reduce cardiovascular disease risk for patients with bipolar disorder
, Contemporary Clinical Trials 33(4): 666-678 (2012)

Design and rationale of a randomized trial comparing the Blalock-Taussig and right ventricle-pulmonary artery shunts in the Norwood procedure
, Journal of Thoracic and Cardiovascular Surgery 136(4): 968-975 (2008)

Design and rationale of a randomized, double-blind, placebo-controlled phase III study for autologous bone marrow cell transplantation in critical limb ischemia: the BONe Marrow Outcomes Trial in Critical Limb Ischemia (BONMOT-CLI)
, Vasa. Zeitschrift für Gefasskrankheiten 37(4): 319-325 (2008)

Design and rationale of a real-life study to compare treatment strategies for cardiovascular risk factors: the CRUCIAL study
, Postgraduate Medicine 122(2): 7-15 (2010)

Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist therapy in patients with heart failure
, American Heart Journal 163(6): 946-953.E1 (2012)

Design and rationale of a study in Asia of atorvastatin pretreatment in patients undergoing percutaneous coronary intervention for non-ST elevation acute coronary syndromes
, Journal of Cardiology 55(3): 303-308 (2010)

Design and rationale of health-related quality of life and patient-reported outcomes assessment in the Frequent Hemodialysis Network trials
, Blood Purification 31(1-3): 151-158 (2011)

Design and rationale of safe pediatric euglycemia after cardiac surgery: a randomized controlled trial of tight glycemic control after pediatric cardiac surgery
, Pediatric Critical Care Medicine 14(2): 148-156 (2013)

Design and rationale of the ANALYZE ST study: a prospective, nonrandomized, multicenter ST monitoring study to detect acute coronary syndrome events in implantable cardioverter-defibrillator patients
, American Heart Journal 168(4): 424-429.E1 (2014)

Design and rationale of the AngioSeal versus the Radial approach In acute coronary SyndromE (ARISE) trial: a randomized comparison of a vascular closure device versus the radial approach to prevent vascular access site complications in non-ST-segment elevation acute coronary syndrome patients
, Trials 14: 435 (2013)

Design and rationale of the Evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) trial
, American Heart Journal 158(5): 726-733 (2009)

Design and rationale of the GAUSS-2 study trial: a double-blind, ezetimibe-controlled phase 3 study of the efficacy and tolerability of evolocumab (AMG 145) in subjects with hypercholesterolemia who are intolerant of statin therapy
, Clinical Cardiology 37(3): 131-139 (2014)

Design and rationale of the LAPLACE-TIMI 57 trial: a phase II, double-blind, placebo-controlled study of the efficacy and tolerability of a monoclonal antibody inhibitor of PCSK9 in subjects with hypercholesterolemia on background statin therapy
, Clinical Cardiology 35(7): 385-391 (2012)

Design and rationale of the PRAGUE-12 trial: a large, prospective, randomized, multicenter trial that compares cardiac surgery with left atrial surgical ablation with cardiac surgery without ablation in patients with coronary and/or valvular heart disease plus atrial fibrillation
, Clinical Cardiology 36(1): 1-5 (2013)

Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function
, Journal of Cardiac Failure 16(1): 25-35 (2010)

Design and rationale of the Paliperidone Palmitate Research in Demonstrating Effectiveness (PRIDE) study: a novel comparative trial of once-monthly paliperidone palmitate versus daily oral antipsychotic treatment for delaying time to treatment failure in persons with schizophrenia
, Journal of Clinical Psychiatry 75(12): 1388-1393 (2014)

Design and rationale of the Reduction of Infarct Expansion and Ventricular Remodeling with Erythropoietin after Large Myocardial Infarction (REVEAL) trial
, American Heart Journal 160(5): 795-803.E2 (2010)

Design and rationale of the TOTAL trial: a randomized trial of routine aspiration ThrOmbecTomy with percutaneous coronary intervention (PCI) versus PCI ALone in patients with ST-elevation myocardial infarction undergoing primary PCI
, American Heart Journal 167(3): 315-321.E1 (2014)

Design and rationale of the TRI-stent adjudication study (TRIAS) program
, American Heart Journal 158(4): 527-532.E1 (2009)

Design and rationale of the URGENT Dyspnea study: an international, multicenter, prospective study
, American Journal of Therapeutics 15(4): 299-303 (2008)

Design and rationale of the WELCOME trial: A randomised, placebo controlled study to test the efficacy of purified long chainomega-3 fatty acid treatment in non-alcoholic fatty liver disease [corrected
, Contemporary Clinical Trials 37(2): 301-311 (2014)

Design and rationale of the WOEST trial: What is the Optimal antiplatElet and anticoagulant therapy in patients with oral anticoagulation and coronary StenTing (WOEST)
, American Heart Journal 158(5): 713-718 (2009)

Design and rationale of the assessment of proper physiologic response with rate adaptive pacing driven by minute ventilation or accelerometer (APPROPRIATE) trial
, Journal of Cardiovascular Translational Research 4(1): 21-26 (2011)

Design and rationale of the comprehensive evaluation of risk factors in older patients with AMI (SILVER-AMI) study
, Bmc Health Services Research 14: 506 (2014)

Design and rationale of the radial versus femoral access for coronary intervention (RIVAL) trial: a randomized comparison of radial versus femoral access for coronary angiography or intervention in patients with acute coronary syndromes
, American Heart Journal 161(2): 254 (2011)

Design and rationale of the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial
, Clinical and Experimental Hypertension 33(7): 455-462 (2011)

Design and rationale of the tobacco, exercise and diet messages (TEXT ME) trial of a text message-based intervention for ongoing prevention of cardiovascular disease in people with coronary disease: a randomised controlled trial protocol
, Bmj Open 2(1): E000606 (2012)

Design and rationale of the treatment of acute coronary syndromes with otamixaban trial: a double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non-ST-segment elevation acute coronary syndromes with a planned early invasive strategy
, American Heart Journal 164(6): 817-24.E13 (2012)

Design and reach of a primary care weight management program
, Journal of Health Care for the Poor and Underserved 19(1): 171-179 (2008)

Design and realisation of star-geometry dual-mode bandpass filter
, Optics Express 13(24): 9753-9757 (2005)

Design and realisation of tissue-equivalent dielectric simulators for dosimetric studies on microwave antennas for interstitial ablation
, Physica Medica 28(3): 245-253 (2012)

Design and realization of X-ray TUBE HEAD control system in the CBCT system
, Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 30(4): 838-842 (2013)

Design and realization of a microarray data analysis platform
, Nan Fang Yi Ke Da Xue Xue Bao 31(4): 610-614 (2011)

Design and realization of a planar ultrawideband antenna with notch band at 3.5 GHz
, Thescientificworldjournal 2014: 563830 (2014)

Design and realization of a two-stage microring ladder filter in silicon-on-insulator
, Optics Express 20(22): 24708-24713 (2012)

Design and realization of a wireless sensor gateway for health monitoring
, Conference Proceedings 2010: 374-377 (2010)

Design and realization of advanced multi-index systems
, Applied Optics 53(4): A88 (2014)

Design and realization of an algorithm for capsule endoscope image recognition system
, Nan Fang Yi Ke Da Xue Xue Bao 32(7): 948-951 (2012)

Design and realization of an all-fiber broadband tunable gain equalization filter for DWDM signals
, Optics Express 15(21): 13519-13530 (2007)

Design and realization of an energy harvester using pulsating arterial pressure
, Medical Engineering and Physics 35(9): 1256-1265 (2013)

Design and realization of reverse presumption system for public health emergencies based on symptoms and signs
, Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 28(8): 616-617 (2010)

Design and realization of the communication system for the mobile medical terminal
, Zhongguo Yi Liao Qi Xie Za Zhi 37(1): 37-39 (2013)

Design and realization of training methods based on sit-to-stand balance ability training apparatus
, Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 30(3): 534 (2013)

Design and receptor interactions of obligate dimeric mutant of chemokine monocyte chemoattractant protein-1 (MCP-1)
, Journal of Biological Chemistry 287(18): 14692-14702 (2012)

Design and recombinant expression of insulin-like peptide 5 precursors and the preparation of mature human INSL5
, Amino Acids 39(5): 1343-1352 (2010)

Design and recombination expression of a novel plectasin-derived peptide MP1106 and its properties against Staphylococcus aureus
, Applied Microbiology and Biotechnology 99(6): 2649-2662 (2015)

Design and recruitment of the Chicago Healthy Living Study: a study of health behaviors in a diverse cohort of adult childhood cancer survivors
, Cancer 115(18 Suppl): 4385-4396 (2009)

Design and redox function of conjugated complexes with polyanilines or quinonediimines
, Accounts of Chemical Research 45(3): 347-360 (2012)

Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part II: Folic acid conjugates of tubulysins and their hydrazides
, Bioorganic and Medicinal Chemistry Letters 18(16): 4558-4561 (2008)

Design and regioselective synthesis of a new generation of targeted therapeutics. Part 3: Folate conjugates of aminopterin hydrazide for the treatment of inflammation
, Bioorganic and Medicinal Chemistry Letters 21(4): 1202-1205 (2011)

Design and regioselective synthesis of trifluoromethylquinolone derivatives as potent antimicrobial agents
, European Journal of Medicinal Chemistry 68: 422-432 (2013)

Design and regulation of efficient photoinduced electron transfer in macromolecular and photosynthetic systems
, Annual Review of Physical Chemistry 46: 453-488 (1995)

Design and reinforcement: vertically aligned carbon nanotube-based sandwich composites
, Acs Nano 4(11): 6798-6804 (2010)

Design and reliability of a novel heel rise test measuring device for plantarflexion endurance
, Biomed Research International 2014: 391646 (2014)

Design and research of an interface compatible non-contacting respiratory signal detection system
, Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 28(3): 465-469 (2011)

Design and research of hospital medical supplies management information system
, Zhongguo Yi Liao Qi Xie Za Zhi 33(2): 140-143 (2009)

Design and results of a culturally tailored cancer outreach project by and for Micronesian women
, Preventing Chronic Disease 9: E82 (2012)

Design and results of an intensive monitoring programme for avian influenza in meat-type turkey flocks during four epidemics in northern Italy
, Zoonoses and Public Health 58(4): 244-251 (2011)

Design and rigorous analysis of high-efficiency array generators
, Applied Optics 32(14): 2599-2605 (1993)

Design and rigorous analysis of transformation-optics scaling devices
, Journal of the Optical Society of America. A Optics Image Science and Vision 30(8): 1698-1702 (2013)

Design and risk assessment tool for vegetative treatment areas receiving agricultural wastewater: preliminary results
, Journal of Environmental Management 91(8): 1794-1801 (2010)

Design and robust tuning of control scheme based on the PD controller plus Disturbance Observer and low-order integrating first-order plus dead-time model
, Isa Transactions 48(4): 410-416 (2009)

Design and roll out of standardised approach to paediatric procedural sedation in Victorian emergency departments
, Emergency Medicine Australasia 25(6): 597-602 (2013)

Design and sample characteristics of the 2005-2008 Nutrition and Health Survey in Taiwan
, Asia Pacific Journal of Clinical Nutrition 20(2): 225-237 (2011)

Design and sample size considerations for simultaneous global drug development program
, Journal of Biopharmaceutical Statistics 22(5): 1060-1073 (2012)

Design and sample size for evaluating combinations of drugs of linear and loglinear dose-response curves
, Journal of Biopharmaceutical Statistics 19(4): 625-640 (2009)

Design and scale-up of an oxidative scrubbing process for the selective removal of hydrogen sulfide from biogas
, Journal of Hazardous Materials 215-216: 49-56 (2012)

Design and scaling of monocentric multiscale imagers
, Applied Optics 51(20): 4691-4702 (2012)

Design and screening of ASIC inhibitors based on aromatic diamidines for combating neurological disorders
, European Journal of Pharmacology 648(1-3): 15-23 (2010)

Design and screening of M13 phage display cDNA libraries
, Molecules 16(2): 1667-1681 (2011)

Design and screening of a glial cell-specific, cell penetrating peptide for therapeutic applications in multiple sclerosis
, Plos one 7(9): E45501 (2012)

Design and screening of siRNAs against highly structured RNA targets
, Methods in Molecular Biology 942: 69-86 (2013)

Design and screening strategies for alpha-glucosidase inhibitors based on enzymological information
, Current Topics in Medicinal Chemistry 9(1): 3-12 (2009)

Design and selection of a camelid single-chain antibody yeast two-hybrid library produced de novo for the cap protein of porcine circovirus type 2 (PCV2)
, Plos one 8(3): E56222 (2013)

Design and selection of a synthetic operon
, Acs Synthetic Biology 3(6): 410-415 (2014)

Design and selection of soy breads used for evaluating isoflavone bioavailability in clinical trials
, Journal of Agricultural and Food Chemistry 61(12): 3111-3120 (2013)

Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand
, Journal of Medicinal Chemistry 56(11): 4568-4579 (2013)

Design and self-assembly of L-glutamate-based aromatic dendrons as ambidextrous gelators of water and organic solvents
, Langmuir 25(15): 8706-8713 (2009)

Design and self-assembly of a leucine-enkephalin analogue in different nanostructures: application of nanovesicles
, Small 8(7): 984-990 (2012)

Design and self-assembly of variform organometallic macrocycle with terminal imidazole-based bridging ligands utilizing joints twist and rotation
, Dalton Transactions 43(6): 2356-2360 (2014)

Design and semiparametric analysis of non-inferiority trials with active and placebo control for censored time-to-event data
, Statistics in Medicine 32(18): 3055-3066 (2013)

Design and semisynthesis of photoactivable split-GFP by incorporation of photocleavable functionality
, Biopolymers 100(6): 773-779 (2013)

Design and sensing properties of an integrated optical gas sensor based on a multilayer structure
, Analytical Chemistry 80(23): 9188-9194 (2008)

Design and signaling mechanism of light-regulated histidine kinases
, Journal of Molecular Biology 385(5): 1433-1444 (2009)

Design and simulated performance of a CARS spectrometer for dynamic temperature measurements using electronic heterodyning
, Applied Optics 28(7): 1409-1416 (1989)

Design and simulation of 1310 nm and 1480 nm single-mode photonic crystal fiber Raman lasers
, Optics Express 16(2): 549-559 (2008)

Design and simulation of 25 Gb/s optical OFDM transceiver ASICs
, Optics Express 19(26): B337 (2011)

Design and simulation of GaN based Schottky betavoltaic nuclear micro-battery
, Applied Radiation and Isotopes 80: 17-22 (2013)

Design and simulation of a GEM-based TEPC as a neutron REM meter
, Radiation Protection Dosimetry 126(1-4): 559-563 (2007)

Design and simulation of a MEMS control moment gyroscope for the sub-kilogram spacecraft
, Sensors 10(4): 4130-4144 (2010)

Design and simulation of a controller system for metabolic shift regulation in mammalian cells
, Bmc Proceedings 5(Suppl. 8): P11 (2011)

Design and simulation of a full-ring multi-lofthole collimator for brain SPECT
, Physics in Medicine and Biology 58(18): 6317-6336 (2013)

Design and simulation of a nanoscale electro-plasmonic 1 × 2 switch based on asymmetric metal-insulator-metal stub filters
, Applied Optics 53(28): 6546-6553 (2014)

Design and simulation of a neutron source based on an electron linear accelerator for BNCT of skin melanoma
, Applied Radiation and Isotopes 69(5): 749-755 (2011)

Design and simulation of a new powered gait orthosis for paraplegic patients
, Prosthetics and Orthotics International 36(1): 125-130 (2012)

Design and simulation of a novel method for determining depth-of-interaction in a PET scintillation crystal array using a single-ended readout by a multi-anode PMT
, Physics in Medicine and Biology 55(13): 3827-3841 (2010)

Design and simulation of a poly(vinyl alcohol)-bacterial cellulose nanocomposite mechanical aortic heart valve prosthesis
, Proceedings of the Institution of Mechanical Engineers. Part H Journal of Engineering in Medicine 223(6): 697-711 (2009)

Design and simulation of a simple laser rangefinder using a semiconductor optical amplifier-detector
, Optics Express 13(10): 3647-3652 (2005)

Design and simulation of a visual and haptic assisted biopsy (ViHAB) system
, Studies in Health Technology and Informatics 132: 514-516 (2008)

Design and simulation of betavoltaic battery using large-grain polysilicon
, Applied Radiation and Isotopes 70(10): 2388-2394 (2012)

Design and simulation of coupled-resonator filters using periodically slotted electrodes on FBARs
, IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 61(5): 881-885 (2014)

Design and simulation of few-cycle optical parametric chirped pulse amplification at mid-IR wavelengths
, Optics Express 16(26): 21297-21304 (2008)

Design and simulation of interference current therapeutic instruments based on FPGA
, Zhongguo Yi Liao Qi Xie Za Zhi 32(2): 100 (2008)

Design and simulation of multimode interference based demultiplexers aided by computer-generated planar holograms
, Optics Express 18(11): 11270 (2010)

Design and simulation of nano-bio sensors for dye molecules targeting to enhance targeting efficiency (smart targeting)
, IEEE Transactions on Nanobioscience 12(1): 21-28 (2013)

Design and simulation of omnidirectional reflective color filters based on metal-dielectric-metal structure
, Optics Express 22(9): 11384-11391 (2014)

Design and simulation of perturbed onion-like quantum-dot-quantum-well (CdSe/ZnS/CdSe/ZnS) and its influence on fluorescence resonance energy transfer mechanism
, Iet Nanobiotechnology 7(4): 140-150 (2013)

Design and simulation of printed spiral coil used in wireless power transmission systems for implant medical devices
, Conference Proceedings 2011: 4018-4021 (2011)

Design and simulation of the NIR micro-spectrometer optical system
, Guang Pu Xue Yu Guang Pu Fen Xi 29(6): 1721-1725 (2009)

Design and simulations of a dynamic polarization-mode dispersion compensator for long-haul optical networks
, Optics Express 11(10): 1166-1174 (2003)

Design and specification criteria for optical data processors
, Applied Optics 7(11): 2285-2288 (1968)

Design and specifications of the diagnostics for the instrumented calorimeter of source for the production of ions of deuterium extracted from radio frequency plasma
, Review of Scientific Instruments 83(2): 02b724 (2012)

Design and stability analysis of fuzzy model-based nonlinear controller for nonlinear systems using genetic algorithm
, IEEE Transactions on Systems Man and Cybernetics. Part B Cybernetics 33(2): 250-257 (2003)

Design and stability analysis of single-input fuzzy logic controller
, IEEE Transactions on Systems Man and Cybernetics. Part B Cybernetics 30(2): 303-309 (2000)

Design and static calibration of a six-dimensional force/torque sensor for minimally invasive surgery
, Minimally Invasive Therapy and Allied Technologies 23(3): 136-143 (2014)

Design and statistical analysis of observational studies
, Bjog 120(7): 901-901 (2013)

Design and statistical analysis of oral medicine studies: common pitfalls
, Oral Diseases 16(3): 233-241 (2010)

Design and statistical methodology of the National Surgical Quality Improvement Program: why is it what it is?
, American Journal of Surgery 198(5 Suppl): S19 (2009)

Design and statistical optimization of osmotically driven capsule based on push-pull technology
, Pharmaceutical Development and Technology 18(2): 515-524 (2013)

Design and statistical properties of robust functional networks: a model study of biological signal transduction
, Physical Review. E Statistical Nonlinear and Soft Matter Physics 75(1 Pt 2): 015101 (2007)

Design and stereoselective preparation of a new class of chiral olefin metathesis catalysts and application to enantioselective synthesis of quebrachamine: catalyst development inspired by natural product synthesis
, Journal of the American Chemical Society 131(3): 943-953 (2009)

Design and stereoselective synthesis of a C-aryl furanoside as a conformationally constrained CHIR-090 analogue
, Carbohydrate Research 359: 59-64 (2012)

Design and stereoselective synthesis of novel isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents
, European Journal of Medicinal Chemistry 65: 70-82 (2013)

Design and stereoselective synthesis of retinoids with ferrocene or N-butylcarbazole pharmacophores that induce post-differentiation apoptosis in acute promyelocytic leukemia cells
, Chemmedchem 6(8): 1518-1529 (2011)

Design and straightforward synthesis of novel galloyl phytosterols with excellent antioxidant activity
, Food Chemistry 163: 171-177 (2014)

Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis
, Chemmedchem 10(1): 116-133 (2015)

Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists
, Journal of Medicinal Chemistry 52(8): 2618-2622 (2009)

Design and structural and thermodynamic studies of a chimeric protein derived from spectrin SH3-domain
, Molekuliarnaia Biologiia 43(3): 483-491 (2009)

Design and structure analysis of artificial metalloproteins: selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold
, Inorganic Chemistry 46(13): 5137-5139 (2007 )

Design and structure of an equilibrium protein folding intermediate: a hint into dynamical regions of proteins
, Journal of Molecular Biology 400(4): 922-934 (2010)

Design and structure of stapled peptides binding to estrogen receptors
, Journal of the American Chemical Society 133(25): 9696-9699 (2011)

Design and studies of novel polyoxysterol-based porphyrin conjugates
, Steroids 77(11): 1169-1175 (2012)

Design and study of a coplanar grid array CdZnTe detector for improved spatial resolution
, Applied Radiation and Isotopes 94: 314-318 (2014)

Design and study of a cost-effective solar photoreactor for pesticide removal from water
, Water Science and Technology 60(8): 2187-2193 (2009)

Design and study of a high resolution vacuum ultraviolet imaging spectrometer carried by satellite
, Guang Pu Xue Yu Guang Pu Fen Xi 31(12): 3417-3422 (2011)

Design and study of lamivudine oral controlled release tablets
, Aaps Pharmscitech 8(4): E101 (2007)

Design and study of parallel computing environment of Monte Carlo simulation for particle therapy planning using a public cloud-computing infrastructure
, Nihon Hoshasen Gijutsu Gakkai Zasshi 69(7): 773-777 (2013)

Design and study of peptide-based inhibitors of amylin cytotoxicity
, Bioorganic and Medicinal Chemistry Letters 20(4): 1360-1362 (2010)

Design and study of the efflux function of the EGFP fused MexAB-OprM membrane transporter in Pseudomonas aeruginosa using fluorescence spectroscopy
, Analyst 139(12): 3088-3096 (2014)

Design and study of ultrasound-based automatic patient movement monitoring device for quantifying the intrafraction motion during teletherapy treatment
, Journal of Applied Clinical Medical Physics 13(6): 3709 (2012)

Design and study protocol of the maternal smoking cessation during pregnancy study, (M-SCOPE)
, Bmc Public Health 11: 903 (2011)

Design and sub-beam phase measurement of Dammann grating with three-phase array output
, Optics Letters 38(15): 2663-2665 (2013)

Design and subspace system identification of an ex vivo vascular perfusion system
, Journal of Biomechanical Engineering 131(4): 041012 (2009)

Design and syntheses of electron-transfer photochromic metal-organic complexes using nonphotochromic ligands: a model compound and the roles of its ligands
, Inorganic Chemistry 53(2): 847-851 (2014)

Design and syntheses of highly emissive aminobenzopyrano-xanthene dyes in the visible and far-red regions
, Organic Letters 16(1): 258-261 (2014)

Design and syntheses of novel N-(benzothiazol-5-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione and N-(benzothiazol-5-yl)isoindoline-1,3-dione as potent protoporphyrinogen oxidase inhibitors
, Journal of Agricultural and Food Chemistry 59(11): 6172-6179 (2011)

Design and syntheses of peptides which induce or enhance structural changes of recombinant bovine prion protein (rbPrP) and discovery of peptides from bovine brain which accelerate structural conversions of rbPrP
, Prion 8(1): 117-118 (2014)

Design and syntheses of permethyl ningalin B analogues: potent multidrug resistance (MDR) reversal agents of cancer cells
, Journal of Medicinal Chemistry 53(14): 5108-5120 (2010)

Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity
, Journal of Medicinal Chemistry 54(18): 6319-6327 (2011)

Design and synthesis of (13S)-methyl-substituted arachidonic acid analogues: templates for novel endocannabinoids
, Chemistry 16(13): 4091-4099 (2010)

Design and synthesis of (2R,3S)-iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter
, Bioorganic and Medicinal Chemistry Letters 19(17): 4996-4998 (2009)

Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists
, Bioorganic and Medicinal Chemistry 21(19): 6077-6083 (2013)

Design and synthesis of (5-amino-1, 2, 4-triazin-6-yl)(2-(benzo[d] isoxazol-3-yl) pyrrolidin-1-yl)methanone derivatives as sodium channel blocker and anticonvulsant agents
, Journal of Enzyme Inhibition and Medicinal Chemistry 29(4): 505-516 (2014)

Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl)ethanol
, Chemical Communications 2009(16): 2133-2135 (2009)

Design and synthesis of (R)-1-arylsulfonylpiperidine-2-carboxamides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors
, Chemmedchem 8(4): 577-581 (2013)

Design and synthesis of (S)- and (R)-enantiomers of [4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(iv) and 2,2-dimethyl-4-phenyl-1,3,2-oxazastannolidine: in vitro antitumor activity against human tumor cell lines and in vivo assay of (S)-enantiomers
, Dalton Transactions 42(10): 3390-3401 (2013)

Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids
, Organic and Biomolecular Chemistry 12(32): 6239-6249 (2014 )

Design and synthesis of 1,2,3-triazole-fused chiral medium-ring benzo-heterocycles, scaffolds mimicking benzolactams
, Journal of Organic Chemistry 77(12): 5399-5405 (2012)

Design and synthesis of 1,3-biarylsulfanyl derivatives as new anti-breast cancer agents
, Bioorganic and Medicinal Chemistry 19(18): 5409-5419 (2011)

Design and synthesis of 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles and pyrazolo[3,4-b]pyridines for Aurora-A kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 20(14): 4273-4278 (2010)

Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors
, European Journal of Medicinal Chemistry 45(6): 2578-2590 (2010)

Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists
, Bioorganic and Medicinal Chemistry Letters 21(8): 2316-2319 (2011)

Design and synthesis of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) analogues as novel probes for the serotonin transporter S1 and S2 binding sites
, Journal of Medicinal Chemistry 56(23): 9709-9724 (2013)

Design and synthesis of 1-(benzothiazol-5-yl)-1H-1,2,4-triazol-5-ones as protoporphyrinogen oxidase inhibitors
, Bioorganic and Medicinal Chemistry 21(11): 3245-3255 (2013)

Design and synthesis of 1-(beta-D-ribofuranosyl)imidazo[4,5-c]pyrazoles as 5:5 bicyclic analogs of purine nucleosides
, Nucleic Acids Symposium Series 2008(52): 593-594 (2008)

Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(9): 2683-2687 (2013)

Design and synthesis of 10-alkoxy-5, 6-dihydro-triazolo[4,3-d]benzo[f][1,4]oxazepine derivatives with anticonvulsant activity
, European Journal of Medicinal Chemistry 45(7): 3080-3086 (2010)

Design and synthesis of 16-membered cyclopeptides active against vancomycin-resistant Enterococci (VRE)
, Chimia 67(12-13): 916-920 (2013)

Design and synthesis of 1H-1,2,3-triazoles derived from econazole as antitubercular agents
, Bioorganic and Medicinal Chemistry Letters 22(22): 6844-6847 (2012)

Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents
, Bioorganic and Medicinal Chemistry 18(11): 4138-4148 (2010)

Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters
, Journal of Medicinal Chemistry 51(9): 2795-2806 (2008)

Design and synthesis of 2-(1, 3-dioxoisoindolin-2-yl)-N-(4-oxo-2-substitutedthiazolidin-3-yl) acetamide derivatives as potential anticonvulsant agents
, European Journal of Medicinal Chemistry 46(11): 5448-5455 (2011)

Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents
, European Journal of Medicinal Chemistry 43(12): 2800-2806 (2008)

Design and synthesis of 2-(3-alkylaminophenyl)-6-(pyrrolidin-1-yl)quinolin-4-ones as potent antitumor agents
, Bioorganic and Medicinal Chemistry Letters 23(3): 699-701 (2013)

Design and synthesis of 2-(3-benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one analogues as potent antitumor agents that inhibit tubulin assembly
, Journal of Medicinal Chemistry 52(15): 4883-4891 (2009)

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators
, Bioorganic and Medicinal Chemistry Letters 23(10): 2936-2940 (2013)

Design and synthesis of 2-acylbenzothiazoles via in situ cross-trapping strategy from benzothiazoles with aryl ketones
, Journal of Organic Chemistry 78(6): 2792-2797 (2013)

Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase
, Journal of Medicinal Chemistry 52(8): 2443-2453 (2009)

Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors
, Bioorganic and Medicinal Chemistry 22(2): 892-905 (2014)

Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 18(19): 5186-5189 (2008)

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors
, Bioorganic and Medicinal Chemistry Letters 18(20): 5648-5652 (2008)

Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA
, Bioorganic and Medicinal Chemistry Letters 22(24): 7719-7725 (2012)

Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae
, Journal of Medicinal Chemistry 53(21): 7664-7674 (2010)

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability
, Journal of Medicinal Chemistry 54(24): 8394-8406 (2011)

Design and synthesis of 2-iminothiazolidin-4-one moiety-containing compounds as potent antiproliferative agents
, Archiv der Pharmazie 345(5): 360-367 (2012)

Design and synthesis of 2-nitroimidazoles with variable alkylating and acylating functionality
, Chemical and Pharmaceutical Bulletin 62(3): 301-303 (2014)

Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents
, Archiv der Pharmazie 343(9): 509-518 (2010)

Design and synthesis of 2-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A
, European Journal of Medicinal Chemistry 66: 180-184 (2013)

Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands
, European Journal of Medicinal Chemistry 46(9): 4252-4257 (2011)

Design and synthesis of 2-phenylnaphthalenoids as inhibitors of DNA topoisomeraseIIα and antitumor agents
, European Journal of Medicinal Chemistry 86: 782-796 (2014)

Design and synthesis of 2-styryl of 5-Nitroimidazole derivatives and antimicrobial activities as FabH inhibitors
, European Journal of Medicinal Chemistry 76: 387-396 (2014)

Design and synthesis of 2-substituted benzoxazoles as novel PTP1B inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(9): 2579-2584 (2013)

Design and synthesis of 2α-(tetrazolylethyl)-1α,25-dihydroxyvitamin D3 as a high affinity ligand for vitamin D receptor
, Journal of Steroid Biochemistry and Molecular Biology 144 Pt A: 201-203 (2014)

Design and synthesis of 3'-fluoropenciclovir analogues as antiviral agents
, Archives of Pharmacal Research 33(2): 197-202 (2010)

Design and synthesis of 3'-methyl-furanonucleosides and their anti-tumor activities
, Yao Xue Xue Bao 44(7): 747-753 (2009)

Design and synthesis of 3,3'-biscoumarin-based c-Met inhibitors
, Organic and Biomolecular Chemistry 12(22): 3721-3734 (2014)

Design and synthesis of 3,4-dihydro-2H-benzo[h]chromene derivatives as potential NF-κB inhibitors
, Bioorganic and Medicinal Chemistry Letters 24(11): 2404-2407 (2014)

Design and synthesis of 3,5-diaryl-4,5-dihydro-1H-pyrazoles as new tyrosinase inhibitors
, Bioorganic and Medicinal Chemistry 21(7): 2156-2162 (2013)

Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents
, Bioorganic and Medicinal Chemistry 17(14): 5285-5292 (2009)

Design and synthesis of 3,5-diarylpiperidin-2,6-diones as anticonvulsant agents
, Bioorganic and Medicinal Chemistry Letters 22(2): 1263-1266 (2012)

Design and synthesis of 3,5-disubstituted boron-containing 1,2,4-oxadiazoles as potential combretastatin A-4 (CA-4) analogs
, Tetrahedron Letters 53(31): 3947-3950 (2012)

Design and synthesis of 3,5-disubstituted-1,2,4-oxadiazoles as potent inhibitors of phosphodiesterase4b2
, Chemical Biology and Drug Design 79(5): 810-818 (2012)

Design and synthesis of 3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-quinolin-2-ones as VEGFR-2 kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(8): 2837-2842 (2012)

Design and synthesis of 3-(4-ethylphenyl)-2-substituted amino-3H-quinazolin-4-ones as a novel class of analgesic and anti-inflammatory agents
, Journal of Enzyme Inhibition and Medicinal Chemistry 23(6): 839-847 (2008)

Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception
, Bioorganic and Medicinal Chemistry Letters 21(1): 176-181 (2011)

Design and synthesis of 3-[(7-chloro-1-oxidoquinolin-4-ylamino)alkyl]-1,3-thiazolidin-4-ones as antimalarial agents
, Journal of Enzyme Inhibition and Medicinal Chemistry 28(5): 1048-1053 (2013)

Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors
, Bioorganic and Medicinal Chemistry Letters 19(12): 3162-3165 (2009)

Design and synthesis of 3-carbamoylbenzoic acid derivatives as inhibitors of human apurinic/apyrimidinic endonuclease 1 (APE1)
, Chemmedchem 7(10): 1825-1839 (2012)

Design and synthesis of 3-isoxazolidone derivatives as new Chlamydia trachomatis inhibitors
, Bioorganic and Medicinal Chemistry Letters 24(16): 3854-3860 (2014)

Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities
, Bioorganic and Medicinal Chemistry Letters 18(19): 5222-5227 (2008)

Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125
, Bioorganic and Medicinal Chemistry 19(1): 172-185 (2011)

Design and synthesis of 3-pyrrol-3-yl-3H-isobenzofuran-1-ones as inhibitors of human cytosolic phospholipase A2alpha
, Journal of Enzyme Inhibition and Medicinal Chemistry 23(6): 946-957 (2008)

Design and synthesis of 3D ordered macroporous CeO₂-supported Pt@CeO(2-δ) core-shell nanoparticle materials for enhanced catalytic activity of soot oxidation
, Small 9(23): 3957-3963 (2013)

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates
, Carbohydrate Research 399: 26-37 (2014)

Design and synthesis of 4,6-substituted-(diaphenylamino)quinazolines as potent EGFR inhibitors with antitumor activity
, Bioorganic and Medicinal Chemistry 20(1): 317-323 (2012)

Design and synthesis of 4-(2,4,5-trifluorophenyl)butane-1,3-diamines as dipeptidyl peptidase IV inhibitors
, Chemmedchem 8(7): 1104-1116 (2013)

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF₁ production
, Bioorganic and Medicinal Chemistry 20(9): 2860-2868 (2012)

Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0(2,6)]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists
, Bioorganic and Medicinal Chemistry Letters 20(15): 4491-4495 (2010)

Design and synthesis of 4-alkyl-2-amino(acetamino)-6-aryl-1,3-thiazine derivatives as influenza neuraminidase inhibitors
, Archiv der Pharmazie 346(9): 635-644 (2013)

Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: a practical access via Pd/C-Cu catalysis
, Bioorganic and Medicinal Chemistry Letters 22(7): 2480-2487 (2012)

Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling
, Bioorganic and Medicinal Chemistry 19(14): 4399-4404 (2011)

Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors
, Bioorganic and Medicinal Chemistry Letters 19(2): 502-507 (2009)

Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands
, Bioorganic and Medicinal Chemistry Letters 21(4): 1236-1242 (2011)

Design and synthesis of 4-heteroaryl 1,2,3,4-tetrahydroisoquinolines as triple reuptake inhibitors
, Acs Medicinal Chemistry Letters 5(7): 760-765 (2014)

Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors
, Journal of Medicinal Chemistry 53(3): 1146-1158 (2010)

Design and synthesis of 5,6-fused heterocyclic amides as Raf kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 21(11): 3286-3289 (2011)

Design and synthesis of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as novel tyrosinase inhibitors
, European Journal of Medicinal Chemistry 49: 245-252 (2012)

Design and synthesis of 5-[(2-chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4-(4-pyrimidinyl)isoxazole (AKP-001), a novel inhibitor of p38 MAP kinase with reduced side effects based on the antedrug concept
, Bioorganic and Medicinal Chemistry 22(15): 4162-4176 (2014)

Design and synthesis of 5-alkoxy-[1,2,4]triazolo[4,3-a]quinoline derivatives with anticonvulsant activity
, European Journal of Medicinal Chemistry 44(3): 954-958 (2009)

Design and synthesis of 5a-carbaglycopyranosylamime glycosidase inhibitors
, Current Topics in Medicinal Chemistry 9(1): 58-75 (2009)

Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(4): 1678-1681 (2012)

Design and synthesis of 6,7-dimethoxyquinazoline analogs as multi-targeted ligands for α1- and AII-receptors antagonism
, Bioorganic and Medicinal Chemistry Letters 23(13): 3959-3966 (2013)

Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase
, Bioorganic and Medicinal Chemistry 21(17): 5064-5075 (2013)

Design and synthesis of 6-fluoro-2-naphthyl derivatives as novel CCR3 antagonists with reduced CYP2D6 inhibition
, Bioorganic and Medicinal Chemistry 16(18): 8607-8618 (2008)

Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors
, European Journal of Medicinal Chemistry 83: 466-473 (2014)

Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors
, Bioorganic and Medicinal Chemistry Letters 19(23): 6591-6594 (2009)

Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1
, Bioorganic and Medicinal Chemistry Letters 18(20): 5609-5613 (2008)

Design and synthesis of 60° dendritic donor ligands and their coordination-driven self-assembly into supramolecular rhomboidal metallodendrimers
, Journal of Organic Chemistry 76(23): 9660-9669 (2011)

Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
, Bioorganic and Medicinal Chemistry Letters 17(20): 5686-5689 (2007)

Design and synthesis of 8-hydroxyquinoline-based radioprotective agents
, Bioorganic and Medicinal Chemistry 22(15): 3891-3905 (2014)

Design and synthesis of 8-substituted benzamido-phenylxanthine derivatives as MAO-B inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(4): 1739-1742 (2012)

Design and synthesis of 99mTc-citro-folate for use as a tumor-targeted radiopharmaceutical
, International Journal of Pharmaceutics 400(1-2): 8-14 (2010)

Design and synthesis of AApeptides: a new class of peptide mimics
, Bioorganic and Medicinal Chemistry Letters 21(5): 1469-1471 (2011)

Design and synthesis of ATP-based nucleotide analogues and profiling of nucleotide-binding proteins
, Bioconjugate Chemistry 22(7): 1345-1353 (2011)

Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta
, Bioorganic and Medicinal Chemistry Letters 18(22): 5955-5958 (2008)

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic
, Bioorganic and Medicinal Chemistry Letters 19(16): 4711-4714 (2009)

Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity
, Journal of Medicinal Chemistry 53(15): 5690-5695 (2010)

Design and synthesis of C-ring lactone- and lactam-based podophyllotoxin analogues as anticancer agents
, Chemical and Pharmaceutical Bulletin 58(2): 242-246 (2010)

Design and synthesis of C-terminal modified cyclic peptides as VEGFR1 antagonists
, Molecules 19(10): 15391-15407 (2014)

Design and synthesis of C2-symmetric N-heterocyclic carbene precursors and metal carbenoids
, Journal of Organic Chemistry 76(18): 7341-7351 (2011)

Design and synthesis of C3-pyrazole/chalcone-linked beta-carboline hybrids: antitopoisomerase I, DNA-interactive, and apoptosis-inducing anticancer agents
, Chemmedchem 9(9): 2084-2098 (2014)

Design and synthesis of C35-fluorinated solamins and their growth inhibitory activities against human cancer cell lines
, Bioorganic and Medicinal Chemistry Letters 21(19): 5745-5749 (2011)

Design and synthesis of CHAP31, trapoxin B and HC-toxin based bicyclic tetrapeptides disulfide as potent histone deacetylase inhibitors
, Bioorganic and Medicinal Chemistry 22(15): 3850-3855 (2014)

Design and synthesis of CK2 inhibitors
, Molecular and Cellular Biochemistry 356(1-2): 91-96 (2011)

Design and synthesis of D-ring steroidal isoxazolines and oxazolines as potential antiproliferative agents against LNCaP, PC-3 and DU-145 cells
, Steroids 87: 93-98 (2014)

Design and synthesis of DNA four-helix bundles
, Nanotechnology 22(23): 235601 (2011)

Design and synthesis of D₁ agonist/D₂ antagonist for treatment of schizophrenia
, Bioorganic and Medicinal Chemistry Letters 23(5): 1498-1501 (2013)

Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis
, Bioorganic and Medicinal Chemistry 20(19): 5901-5914 (2012)

Design and synthesis of FRET-mediated multicolor and photoswitchable fluorescent polymer nanoparticles with tunable emission properties
, Journal of Physical Chemistry. B 116(14): 4354-4362 (2012)

Design and synthesis of Fmoc-Thr[PO(OH)(OPOM)] for the preparation of peptide prodrugs containing phosphothreonine in fully protected form
, Chemistry and Biodiversity 11(5): 784-791 (2014)

Design and synthesis of HCV agents with sequential triple inhibitory potentials
, Bioorganic and Medicinal Chemistry Letters 20(17): 5212-5216 (2010)

Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application
, Bioorganic and Medicinal Chemistry Letters 23(1): 310-317 (2013)

Design and synthesis of Hsp90 inhibitors: exploring the SAR of Sansalvamide A derivatives
, Bioorganic and Medicinal Chemistry 18(18): 6822-6856 (2010)

Design and synthesis of ICT-based fluorescent probe for high-sensitivity protein detection and application to rapid protein staining for SDS-PAGE
, Proteomics 8(14): 2785-2790 (2008)

Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration
, Bioorganic and Medicinal Chemistry Letters 20(21): 6302-6305 (2010)

Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase
, Bioorganic and Medicinal Chemistry 21(11): 3262-3271 (2013)

Design and synthesis of LNA-based mercaptoacetamido-linked nucleoside dimers
, Nucleosides Nucleotides and Nucleic Acids 32(5): 256-272 (2013)

Design and synthesis of Lapatinib derivatives containing a branched side chain as HER1/HER2 targeting antitumor drug candidates
, European Journal of Medicinal Chemistry 87: 631-642 (2014)

Design and synthesis of MMP inhibitors with appended fluorescent tags for imaging and visualization of matrix metalloproteinase enzymes
, Bioorganic and Medicinal Chemistry Letters 23(20): 5566-5570 (2013)

Design and synthesis of MnO₂/Mn/MnO₂ sandwich-structured nanotube arrays with high supercapacitive performance for electrochemical energy storage
, Nano Letters 12(7): 3803-3807 (2012)

Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists
, Bioorganic and Medicinal Chemistry 17(23): 8003-8011 (2009)

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors
, Bioorganic and Medicinal Chemistry 16(7): 3926-3932 (2008)

Design and synthesis of N-2,6-difluorophenyl-5-methoxyl-1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor
, Bioorganic and Medicinal Chemistry 17(8): 3011-3017 (2009)

Design and synthesis of N-acylated aza-goniothalamin derivatives and evaluation of their in vitro and in vivo antitumor activity
, Chemmedchem 9(12): 2725-2743 (2014)

Design and synthesis of N-alkyl-N'-substituted 2,4-dioxo-3,4-dihydropyrimidin-1-diacylhydrazine derivatives as ecdysone receptor agonist
, Bioorganic and Medicinal Chemistry 21(15): 4687-4697 (2013)

Design and synthesis of N-alkyldeoxynojirimycin derivatives with improved metabolic stability as inhibitors of BVDV and Tacaribe virus
, Bioorganic and Medicinal Chemistry Letters 23(14): 4258-4262 (2013)

Design and synthesis of N-aryl isothioureas as a novel class of gastric H(+) /K(+) -ATPase inhibitors
, Archiv der Pharmazie 346(12): 891-900 (2013)

Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents
, Bioorganic and Medicinal Chemistry Letters 21(10): 2916-2920 (2011)

Design and synthesis of N-phosphoryl peptide modified podophyllotoxin derivatives as potent anticancer agents
, Protein and Peptide Letters 18(12): 1258-1264 (2011)

Design and synthesis of N-substituted indazole-3-carboxamides as poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors(†)
, Chemical Biology and Drug Design 79(4): 488-496 (2012)

Design and synthesis of N4,N9-disubstituted spermines for non-viral siRNA delivery--structure-activity relationship studies of siFection efficiency versus toxicity
, Pharmaceutical Research 26(2): 286-295 (2009)

Design and synthesis of N¹,N⁵-bis[4-(5-alkyl-1,2,4-oxadiazol-3-yl)phenyl]glutaramides as potential antifungal prodrugs
, Molecules 18(9): 11250-11263 (2013)

Design and synthesis of N₁-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors
, Bioorganic and Medicinal Chemistry 22(4): 1459-1467 (2014)

Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations
, Carbohydrate Research 346(9): 1083-1092 (2011)

Design and synthesis of P1-P3 macrocyclic tertiary-alcohol-comprising HIV-1 protease inhibitors
, Journal of Medicinal Chemistry 56(22): 8999-9007 (2013)

Design and synthesis of Pd-MnO2 nanolamella-graphene composite as a high-performance multifunctional electrocatalyst towards formic acid and methanol oxidation
, Physical Chemistry Chemical Physics 15(25): 10367-10375 (2013)

Design and synthesis of Pictet-Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death
, Bioorganic and Medicinal Chemistry Letters 22(17): 5707-5713 (2012)

Design and synthesis of Raman reporter molecules for tissue imaging by immuno-SERS microscopy
, Journal of Biophotonics 4(6): 453-463 (2011)

Design and synthesis of Selenazole-containing peptides for cocrystallization with P-glycoprotein
, Chembiochem 12(6): 868-873 (2011)

Design and synthesis of Trypanosoma brucei active 1-alkyloxy and 1-benzyloxyadamantano 2-guanylhydrazones
, Chemmedchem 4(7): 1059-1062 (2009)

Design and synthesis of Tröger's base ditopic receptors: host-guest interactions, a combined theoretical and experimental study
, Organic and Biomolecular Chemistry 13(4): 1141-1149 (2015)

Design and synthesis of a 3,4-dehydroproline amide discovery library
, Journal of Combinatorial Chemistry 9(4): 677-683 (2007)

Design and synthesis of a FlAsH-type Mg2+ fluorescent probe for specific protein labeling
, Journal of the American Chemical Society 136(6): 2374-2381 (2014)

Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker
, Journal of Combinatorial Chemistry 11(1): 72-82 (2009)

Design and synthesis of a Magainin2 fusion protein gene suitable for a mammalian expression system
, Transgenic Research 18(1): 99-112 (2009)

Design and synthesis of a beta-lactamase activated 5-fluorouracil prodrug
, Bioorganic and Medicinal Chemistry Letters 19(4): 1261-1263 (2009)

Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin
, Molecules 18(10): 11783-11796 (2013)

Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76
, Bioorganic and Medicinal Chemistry Letters 21(18): 5324-5327 (2011)

Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5
, Organic and Biomolecular Chemistry 10(13): 2633-2646 (2012)

Design and synthesis of a bombesin peptide-conjugated tripodal phosphino dithioether ligand topology for the stabilization of the fac-[M(CO)3]+ core (M=(99 m)Tc or Re)
, Inorganic Chemistry 50(13): 6210-6219 (2011)

Design and synthesis of a caged Zn2+ probe, 8-benzenesulfonyloxy-5-N,N-dimethylaminosulfonylquinolin-2-ylmethyl-pendant 1,4,7,10-tetraazacyclododecane, and its hydrolytic uncaging upon complexation with Zn2+
, Inorganic Chemistry 47(7): 2747-2754 (2008)

Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1
, Plos one 9(9): E107432 (2014)

Design and synthesis of a coumarin-based acidichromic colorant
, Molecules 12(7): 1316-1324 (2007)

Design and synthesis of a cyclic double mutant peptide (cyclo(87-99)[A91,A96]MBP87-99) induces altered responses in mice after conjugation to mannan: implications in the immunotherapy of multiple sclerosis
, Journal of Medicinal Chemistry 52(1): 214-218 (2009)

Design and synthesis of a cyclitol-derived scaffold with axial pyridyl appendages and its encapsulation of the silver(I) cation
, Beilstein Journal of Organic Chemistry 6: 1022-1024 (2010)

Design and synthesis of a dual linker for solid phase synthesis of oleanolic acid derivatives
, Molecules 16(6): 4748-4763 (2011)

Design and synthesis of a fluorescent probe for Zn2+, 5,7-bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-pendant 1,4,7,10-tetraazacyclododecane and Zn2+-dependent hydrolytic and Zn2+-independent photochemical reactivation of its benzenesulfonyl-caged derivative
, Inorganic Chemistry 49(3): 888-899 (2010)

Design and synthesis of a gossypol derivative with improved antitumor activities
, Archiv der Pharmazie 342(4): 223-229 (2009)

Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells
, Organic and Biomolecular Chemistry 8(16): 3627-3630 (2010)

Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)
, Bioorganic and Medicinal Chemistry 20(3): 1271-1280 (2012)

Design and synthesis of a highly sensitive off-on fluorescent chemosensor for zinc ions utilizing internal charge transfer
, Chemistry 16(2): 568-572 (2010)

Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods
, Angewandte Chemie 48(50): 9557-9560 (2009)

Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR
, Bioorganic and Medicinal Chemistry Letters 20(1): 87-91 (2010)

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor
, European Journal of Medicinal Chemistry 78: 401-418 (2014)

Design and synthesis of a library of BODIPY-based environmental polarity sensors utilizing photoinduced electron-transfer-controlled fluorescence ON/OFF switching
, Journal of the American Chemical Society 129(17): 5597-5604 (2007)

Design and synthesis of a library of chemokine antagonists
, Bioorganic and Medicinal Chemistry Letters 21(21): 6249-6252 (2011)

Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors
, Plos one 9(3): E87851 (2014)

Design and synthesis of a library of tetracyclic hydroazulenoisoindoles
, Journal of Combinatorial Chemistry 11(3): 486-494 (2009)

Design and synthesis of a long-wavelength latent fluorogenic substrate for salicylate hydroxylase: a useful fluorimetric indicator for analyte determination by dehydrogenase-coupled biosensors
, Analytical Chemistry 82(17): 7329-7334 (2010)

Design and synthesis of a luminescent cyclometalated iridium(III) complex having N,N-diethylamino group that stains acidic intracellular organelles and induces cell death by photoirradiation
, Inorganic Chemistry 51(23): 12697-12706 (2012)

Design and synthesis of a macrosphelide A-biotin chimera
, Organic and Biomolecular Chemistry 12(36): 7127-7135 (2014)

Design and synthesis of a metabolically stable and potent antitussive agent, a novel delta opioid receptor antagonist, TRK-851
, Bioorganic and Medicinal Chemistry 16(17): 7956-7967 (2008)

Design and synthesis of a mitochondria-targeting carrier for small molecule drugs
, Organic and Biomolecular Chemistry 12(48): 9793-9796 (2014)

Design and synthesis of a near-infrared fluorescent nanofiber precursor for detecting cell-secreted urokinase activity
, Analytical Biochemistry 412(1): 26-33 (2011)

Design and synthesis of a new class of 4-aminoquinolinyl- and 9-anilinoacridinyl Schiff base hydrazones as potent antimalarial agents
, Chemical Biology and Drug Design 84(2): 175-181 (2014)

Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities
, Bioorganic and Medicinal Chemistry Letters 20(20): 6088-6092 (2010)

Design and synthesis of a new class of membrane-permeable triazaborolopyridinium fluorescent probes
, Journal of the American Chemical Society 133(17): 6780-6790 (2011)

Design and synthesis of a new class of photochromic diarylethene-containing dithieno[3,2-b:2',3'-d]pyrroles and their switchable luminescence properties
, Chemistry 15(39): 10005 (2009)

Design and synthesis of a new class of selective integrin alpha5beta1 antagonists
, Journal of Medicinal Chemistry 50(16): 3786-3794 (2007)

Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage
, Organic and Biomolecular Chemistry 12(47): 9572-9582 (2014)

Design and synthesis of a new family of fluorinated liquid crystals
, Chemistry 19(7): 2370-2383 (2013)

Design and synthesis of a new layered thermoelectric material LaPbBiS3O
, Inorganic Chemistry 53(20): 11125 (2014)

Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors
, European Journal of Pharmaceutical Sciences 62: 334-341 (2014)

Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors
, European Journal of Medicinal Chemistry 82: 600-611 (2014)

Design and synthesis of a new terbium complex-based luminescent probe for time-resolved luminescence sensing of zinc ions
, Journal of Fluorescence 24(5): 1537-1544 (2014)

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions
, Bioorganic and Medicinal Chemistry Letters 18(22): 5926-5931 (2008)

Design and synthesis of a novel anchoring ligand for highly efficient thin film dye-sensitized solar cells
, Chemical Communications 2009(46): 7146-7148 (2009)

Design and synthesis of a novel anthracene-based fluorescent probe through the application of the Suzuki-Miyaura cross-coupling reaction
, Amino Acids 35(1): 169-173 (2008)

Design and synthesis of a novel cationic thiolated polymer
, International Journal of Pharmaceutics 411(1-2): 10-17 (2011)

Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles
, Organic and Biomolecular Chemistry 10(25): 4907-4915 (2012)

Design and synthesis of a novel fluorescence probe for Zn2+ based on the spirolactam ring-opening process of rhodamine derivatives
, Bioorganic and Medicinal Chemistry 19(3): 1072-1078 (2011)

Design and synthesis of a novel fluorescent protein probe for easy and rapid electrophoretic gel staining by using a commonly available UV-based fluorescent imaging system
, Electrophoresis 34(17): 2464-2472 (2013)

Design and synthesis of a novel ganglioside ligand for influenza A viruses
, Molecules 17(8): 9590-9620 (2012)

Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR
, Bioorganic and Medicinal Chemistry Letters 22(15): 5098-5103 (2012)

Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain
, Journal of Medicinal Chemistry 51(16): 4932-4947 (2008)

Design and synthesis of a novel series of bicyclic heterocycles as potent γ-secretase modulators
, Journal of Medicinal Chemistry 55(21): 9089-9106 (2012)

Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors
, Journal of Medicinal Chemistry 51(21): 6761-6772 (2008)

Design and synthesis of a novel three-hindered quadrant bisphosphine ligand and its application in asymmetric hydrogenation
, Chemical Communications 46(45): 8555-8557 (2010)

Design and synthesis of a novel triptycene-based ligand for modeling carboxylate-bridged diiron enzyme active sites
, Organic Letters 13(19): 5052-5055 (2011)

Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor
, Bioorganic and Medicinal Chemistry Letters 21(6): 1838-1843 (2011)

Design and synthesis of a photoaromatization-based two-stage photobase generator for pitch division lithography
, Journal of Organic Chemistry 78(5): 1730-1734 (2013)

Design and synthesis of a photocleavable biotin-linker for the photoisolation of ligand-receptor complexes based on the photolysis of 8-quinolinyl sulfonates in aqueous solution
, Bioorganic and Medicinal Chemistry 17(9): 3405-3413 (2009)

Design and synthesis of a photoswitchable guanidine catalyst
, Beilstein Journal of Organic Chemistry 8: 1825-1830 (2012)

Design and synthesis of a potent peptide containing both specific and non-specific cell-adhesion motifs
, Biomaterials 31(18): 4809-4817 (2010)

Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffold
, Tetrahedron 67(52): 10216-10221 (2011)

Design and synthesis of a quintessential self-transmissible IncX1 plasmid, pX1.0
, Plos one 6(5): E19912 (2011)

Design and synthesis of a ratiometric fluorescent chemosensor for Cu(II) with a fluorophore hybridization approach
, Organic Letters 14(17): 4378-4381 (2012)

Design and synthesis of a reagent for solid-phase incorporation of the phosphothreonine mimetic (2S,3R)-2-amino-3-methyl-4-phosphonobutyric acid (Pmab) into peptides in a bio-reversible phosphonyl-bis-pivaloyloxymethyl (POM) prodrug form
, Amino Acids 45(5): 1143-1148 (2013)

Design and synthesis of a ruthenium(II) complex-based luminescent probe for highly selective and sensitive luminescence detection of nitric oxide
, Journal of Fluorescence 23(6): 1113-1120 (2013)

Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors
, European Journal of Medicinal Chemistry 54: 311-323 (2012)

Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors
, Bioorganic and Medicinal Chemistry Letters 18(19): 5249-5251 (2008)

Design and synthesis of a series of novel bisquinazoline glycosides as epidermal growth factor receptor inhibitors
, Chemical Biology and Drug Design 78(6): 1006-1013 (2011)

Design and synthesis of a series of piperazine-1-carboxamidine derivatives with antifungal activity resulting from accumulation of endogenous reactive oxygen species
, Chemmedchem 4(10): 1714-1721 (2009)

Design and synthesis of a series of pyrido[2,3-d]pyrimidine derivatives as CCR4 antagonists
, Molecules 17(8): 9961-9970 (2012)

Design and synthesis of a series of α-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility
, Bioorganic and Medicinal Chemistry 21(8): 2319-2332 (2013)

Design and synthesis of a simplified inhibitor for XIAP-BIR3 domain
, Bioorganic and Medicinal Chemistry Letters 19(22): 6413-6418 (2009)

Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors
, Journal of Medicinal Chemistry 55(18): 8178-8182 (2012)

Design and synthesis of a stable supramolecular trigonal prism formed by the self-assembly of a linear tetrakis(Zn2+-cyclen) complex and trianionic trithiocyanuric acid in aqueous solution and its complexation with DNA (cyclen = 1,4,7,10-tetraazacyclododecane)
, Inorganic Chemistry 48(19): 9567-9578 (2009)

Design and synthesis of a terbium(III) complex-based luminescence probe for time-gated luminescence detection of mercury(II) ions
, Journal of Fluorescence 22(1): 261-267 (2012)

Design and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site
, Organic and Biomolecular Chemistry 8(7): 1666-1673 (2010)

Design and synthesis of a tetrahydroisoquinoline-based hydroxamate derivative (ZYJ-34v), an oral active histone deacetylase inhibitor with potent antitumor activity
, Chemical Biology and Drug Design 82(2): 125-130 (2013)

Design and synthesis of a universal antigen to detect brucellosis
, Angewandte Chemie 52(28): 7181-7185 (2013)

Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes
, Bioorganic and Medicinal Chemistry Letters 22(7): 2385-2387 (2012)

Design and synthesis of a "click" high-mannose oligosaccharide mimic emulating Man8 binding affinity towards Con A
, Chemical Communications 48(31): 3733-3735 (2012)

Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: potent and selective beta-N-acetylhexosaminidase inhibitors
, Bioorganic and Medicinal Chemistry 17(15): 5598-5604 (2009)

Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells
, Journal of Medicinal Chemistry 55(7): 3201-3215 (2012)

Design and synthesis of active vitamin D analogs
, Journal of Steroid Biochemistry and Molecular Biology 121(1-2): 7-12 (2010)

Design and synthesis of affinity ligands and relation of their structure with adsorption of proteins
, Journal of Separation Science 34(22): 3145-3150 (2011)

Design and synthesis of alkoxyindolyl-3-acetic acid analogs as peroxisome proliferator-activated receptor-γ/δ agonists
, Bioorganic and Medicinal Chemistry Letters 23(2): 513-517 (2013)

Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists
, Organic and Biomolecular Chemistry 5(12): 1915-1923 (2007)

Design and synthesis of alpha-helical peptides and mimetics
, Organic and Biomolecular Chemistry 5(22): 3577-3585 (2007)

Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
, Journal of Medicinal Chemistry 53(11): 4545-4549 (2010)

Design and synthesis of amide derivatives as S-adenosyl-L-homocysteine hydrolase inhibitors
, Chemical and Pharmaceutical Bulletin 62(1): 112-117 (2014)

Design and synthesis of amidine-type peptide bond isosteres: application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis
, Organic and Biomolecular Chemistry 9(9): 3421-3427 (2011)

Design and synthesis of aminohydantoins as potent and selective human β-secretase (BACE1) inhibitors with enhanced brain permeability
, Bioorganic and Medicinal Chemistry Letters 20(22): 6597-6605 (2010)

Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors
, Chemmedchem 9(11): 2565-2579 (2014)

Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity
, Journal of Medicinal Chemistry 56(6): 2359-2373 (2013)

Design and synthesis of an ER-specific fluorescent probe based on carboxylesterase activity with quinone methide cleavage process
, Bioorganic and Medicinal Chemistry Letters 21(11): 3206-3209 (2011)

Design and synthesis of an Fmoc-SPPS-compatible amino acid building block mimicking the transition state of phosphohistidine phosphatase
, Journal of Organic Chemistry 77(4): 2047-2052 (2012)

Design and synthesis of an all-in-one 3-(1,1-difluoroprop-2-ynyl)-3H-diazirin-3-yl functional group for photo-affinity labeling
, Bioorganic and Medicinal Chemistry 17(15): 5388-5395 (2009)

Design and synthesis of an aminopiperidine series of γ-secretase modulators
, Bioorganic and Medicinal Chemistry Letters 24(1): 378-381 (2014)

Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer
, Bioorganic and Medicinal Chemistry 18(23): 8150-8157 (2010)

Design and synthesis of an antigenic mimic of the Ebola glycoprotein
, Journal of Materials Research 23(12): 3161-3168 (2008)

Design and synthesis of an o-hydroxyphenyl-containing spiropyran thermochromic colorant
, Organic Letters 11(8): 1769-1772 (2009)

Design and synthesis of an on-off "click" fluorophore that executes a logic operation and detects heavy and transition metal ions in water and living cells
, Organic and Biomolecular Chemistry 11(18): 3057-3063 (2013)

Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats
, Journal of Medicinal Chemistry 54(1): 342-353 (2011)

Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047)
, Journal of Medicinal Chemistry 52(9): 3028-3038 (2009)

Design and synthesis of an ¹⁸F-labeled version of phenylethyl orvinol ([¹⁸F]FE-PEO) for PET-imaging of opioid receptors
, Molecules 17(10): 11554-11569 (2012)

Design and synthesis of androgen receptor antagonists with bulky side chains for overcoming antiandrogen resistance
, Journal of Medicinal Chemistry 52(17): 5546-5550 (2009)

Design and synthesis of androgen receptor full antagonists bearing a p-carborane cage: promising ligands for anti-androgen withdrawal syndrome
, Journal of Medicinal Chemistry 53(13): 4917-4926 (2010)

Design and synthesis of anti-MRSA benzimidazolylbenzene-sulfonamides. QSAR studies for prediction of antibacterial activity
, Molecules 16(1): 175-189 (2010)

Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach
, Bioorganic and Medicinal Chemistry 18(4): 1563-1572 (2010)

Design and synthesis of anti-cancer cyclopeptides containing triazole skeleton
, Amino Acids 46(4): 1033-1046 (2014)

Design and synthesis of antifreeze glycoproteins and mimics
, Chembiochem 11(18): 2489-2498 (2010)

Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping
, European Journal of Medicinal Chemistry 46(5): 1706-1712 (2011)

Design and synthesis of antioxidant alpha-lipoic acid hybrids
, Methods in Molecular Biology 594: 297-309 (2010 )

Design and synthesis of aralkyl-ketone piperazine derivatives and their antalgic activities
, Yao Xue Xue Bao 42(11): 1166-1175 (2007)

Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors
, Bioorganic and Medicinal Chemistry Letters 21(1): 324-328 (2011)

Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase
, Chemmedchem 3(8): 1250-1268 (2008)

Design and synthesis of aryl sulfonamide-based nonsteroidal mineralocorticoid receptor antagonists
, Bioorganic and Medicinal Chemistry Letters 23(23): 6239-6242 (2013)

Design and synthesis of arylthiophene-2-carbaldehydes via Suzuki-Miyaura reactions and their biological evaluation
, Molecules 18(12): 14711-14725 (2013)

Design and synthesis of aza-flavones as a new class of xanthine oxidase inhibitors
, Archiv der Pharmazie 346(1): 7-16 (2013)

Design and synthesis of azaisoflavone analogs as phytoestrogen mimetics
, European Journal of Medicinal Chemistry 85: 107-118 (2014)

Design and synthesis of azolopyrimidoquinolines, pyrimidoquinazolines as anti-oxidant, anti-inflammatory and analgesic activities
, European Journal of Medicinal Chemistry 44(2): 609-624 (2009)

Design and synthesis of backbone cyclic phosphopeptides: the IkappaB model
, Advances in Experimental Medicine and Biology 611: 139-140 (2009)

Design and synthesis of backbone cyclic phosphorylated peptides: The IkappaB model
, Biopolymers 91(2): 157-168 (2009)

Design and synthesis of benzenesulfonamide derivatives as potent anti-influenza hemagglutinin inhibitors
, Acs Medicinal Chemistry Letters 2(8): 603-607 (2011)

Design and synthesis of benzimidazole analogs endowed with oxadiazole as selective COX-2 inhibitor
, Archiv der Pharmazie 347(12): 923-935 (2014)

Design and synthesis of benzo[c,d]indolone-pyrrolobenzodiazepine conjugates as potential anticancer agents
, Bioorganic and Medicinal Chemistry 20(2): 789-800 (2012)

Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1
, Bioorganic and Medicinal Chemistry Letters 20(13): 3897-3902 (2010)

Design and synthesis of benzosultine-sulfone as a o-xylylene precursor via cross-enyne metathesis and rongalite: further expansion to polycyclics via regioselective Diels-Alder reaction
, Journal of Organic Chemistry 75(12): 4319-4322 (2010)

Design and synthesis of benzoxazole containing indole analogs as peroxisome proliferator-activated receptor-γ/δ dual agonists
, Bioorganic and Medicinal Chemistry Letters 21(10): 3057-3061 (2011)

Design and synthesis of benzoylphenylureas with fluorinated substituents on the aniline ring as insect growth regulators
, Journal of Agricultural and Food Chemistry 59(6): 2471-2477 (2011)

Design and synthesis of biaryl aryl stilbenes/ethylenes as antimicrotubule agents
, European Journal of Medicinal Chemistry 60: 305-324 (2013)

Design and synthesis of bicyclic heterocycles as potent γ-secretase modulators
, Bioorganic and Medicinal Chemistry Letters 23(17): 4794-4800 (2013)

Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(6): 1604-1607 (2013)

Design and synthesis of bile acid-based amino sterols as antimicrobial agents
, Bioorganic and Medicinal Chemistry Letters 19(18): 5411-5414 (2009)

Design and synthesis of bile acid-peptide conjugates linked via triazole moiety
, Organic and Biomolecular Chemistry 9(13): 4921-4926 (2011)

Design and synthesis of bimetallic electrocatalyst with multilayered Pt-skin surfaces
, Journal of the American Chemical Society 133(36): 14396-14403 (2011)

Design and synthesis of binding growth factors
, International Journal of Molecular Sciences 13(5): 6053-6072 (2012)

Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines
, European Journal of Medicinal Chemistry 45(11): 5022-5030 (2010)

Design and synthesis of biofunctionalized metallic/magnetic nanomaterials
, Methods in Molecular Biology 751: 583-595 (2011)

Design and synthesis of biologically active peptides: a 'tail' of amino acids can modulate activity of synthetic cyclic peptides
, Peptides 32(12): 2504-2510 (2011)

Design and synthesis of biomimetic multicomponent all-bone-minerals bionanocomposites
, Biomacromolecules 11(10): 2545-2549 (2010)

Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182
, Bioorganic and Medicinal Chemistry 21(7): 2079-2087 (2013)

Design and synthesis of biotin-tagged photoaffinity probes of jasmonates
, Bioorganic and Medicinal Chemistry 18(9): 3012-3019 (2010)

Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-κB components
, Bioorganic and Medicinal Chemistry Letters 21(21): 6293-6296 (2011)

Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain
, Bioorganic and Medicinal Chemistry 19(22): 6833-6841 (2011)

Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques
, Organic and Biomolecular Chemistry 6(10): 1822-1830 (2008)

Design and synthesis of biphenyl derivatives as mushroom tyrosinase inhibitors
, Bioorganic and Medicinal Chemistry 18(18): 6708-6714 (2010)

Design and synthesis of bipyridine platinum(II) bisalkynyl fullerene donor-chromophore-acceptor triads with ultrafast charge separation
, Journal of the American Chemical Society 136(28): 10041-10052 (2014)

Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents
, European Journal of Medicinal Chemistry 65: 348-359 (2013)

Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors
, Molecules 13(10): 2442-2461 (2008)

Design and synthesis of bis-biotin-containing reagents for applications utilizing monoclonal antibody-based pretargeting systems with streptavidin mutants
, Bioconjugate Chemistry 21(7): 1225-1238 (2010)

Design and synthesis of bis-carbamate analogs of cyclic bis-(3'-5')-diguanylic acid (c-di-GMP) and the acyclic dimer PGPG
, Nucleosides Nucleotides and Nucleic Acids 27(12): 1282-1300 (2008)

Design and synthesis of bistereogenic chiral ionic liquids and their use as solvents for asymmetric Baylis-Hillman reactions
, Organic and Biomolecular Chemistry 6(17): 3041-3043 (2008)

Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: overview and perspectives
, European Journal of Medicinal Chemistry 43(11): 2298-2306 (2008)

Design and synthesis of boron containing potential pan-RAR inverse agonists
, Tetrahedron Letters 53(11): 1316-1318 (2012)

Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application
, Bioorganic and Medicinal Chemistry Letters 20(7): 2270-2274 (2010)

Design and synthesis of boronic acid inhibitors of endothelial lipase
, Bioorganic and Medicinal Chemistry Letters 22(3): 1397-1401 (2012)

Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
, Bioorganic and Medicinal Chemistry Letters 21(18): 5521-5527 (2011)

Design and synthesis of branched platinum-acetylide complexes possessing a porphyrin core and their self-assembly behaviour
, Chemical Communications 48(91): 11223 (2012)

Design and synthesis of caffeoyl-anilides as portmanteau inhibitors of HIV-1 integrase and CCR5
, Bioorganic and Medicinal Chemistry 19(3): 1256-1263 (2011)

Design and synthesis of caged fluorescent nucleotides and application to live-cell RNA imaging
, Chembiochem 12(18): 2871-2880 (2011)

Design and synthesis of calcium responsive magnetic resonance imaging agent: Its relaxation and luminescence studies
, European Journal of Medicinal Chemistry 82: 225-232 (2014)

Design and synthesis of calixarene-based bis-alkynyl-bridged dinuclear Au(I) isonitrile complexes as luminescent ion probes by the modulation of Au..Au interactions
, Chemistry 15(35): 8842-8851 (2009)

Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives
, European Journal of Medicinal Chemistry 44(3): 1331-1334 (2009)

Design and synthesis of cannabinoid receptor 1 antagonists for peripheral selectivity
, Journal of Medicinal Chemistry 55(6): 2820-2834 (2012)

Design and synthesis of carbamate and thiocarbamate derivatives and their inhibitory activities of NO production in LPS activated macrophages
, Bioorganic and Medicinal Chemistry Letters 22(9): 3301-3304 (2012)

Design and synthesis of carbocyclic versions of furanoid nucleoside phosphonic Acid analogues as potential anti-hiv agents
, Nucleosides Nucleotides and Nucleic Acids 30(10): 798-813 (2011)

Design and synthesis of carbon-11-labeled dual aromatase-steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer
, Steroids 74(12): 896-905 (2009)

Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring
, Bioorganic and Medicinal Chemistry 16(17): 8022-8028 (2008)

Design and synthesis of catenated rings based on toroidal DNA structures
, Chemical Communications 47(43): 11930 (2011)

Design and synthesis of cationic drug carriers based on hyperbranched poly(amine-ester)s
, Biomacromolecules 11(3): 575-582 (2010)

Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents
, Bioorganic and Medicinal Chemistry Letters 19(22): 6386-6391 (2009)

Design and synthesis of cellulose derivatives with antioxidant activity
, Macromolecular Bioscience 8(1): 86-95 (2008)

Design and synthesis of chiral N-chloroimidodicarbonates: application to asymmetric chlorination of silyl enol ethers
, Journal of Organic Chemistry 72(13): 4872-4876 (2007)

Design and synthesis of chiral Zn2+ complexes mimicking natural aldolases for catalytic C-C bond forming reactions in aqueous solution
, International Journal of Molecular Sciences 15(2): 2087-2118 (2014)

Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines
, Angewandte Chemie 52(26): 6713-6717 (2013)

Design and synthesis of chloroquine analogs with anti-breast cancer property
, European Journal of Medicinal Chemistry 45(9): 3916-3923 (2010)

Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors
, Chemical and Pharmaceutical Bulletin 56(10): 1400-1405 (2008)

Design and synthesis of cleavable biotinylated dideoxynucleotides for DNA sequencing by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
, Analytical Biochemistry 427(2): 193-201 (2012)

Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonists
, Bioorganic and Medicinal Chemistry Letters 20(7): 2311-2315 (2010)

Design and synthesis of conformationally constrained analogues of cis-cinnamic acid and evaluation of their plant growth inhibitory activity
, Phytochemistry 96: 223-234 (2013)

Design and synthesis of conformationally constrained cyclophilin inhibitors showing a cyclosporin-A phenotype in C. elegans
, Chembiochem 12(5): 802-810 (2011)

Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase
, Journal of Medicinal Chemistry 54(22): 7920-7933 (2011)

Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazole heterocycle reveal a novel family of transient receptor potential vanilloid 1 (TRPV1) antagonists
, European Journal of Medicinal Chemistry 66: 193-203 (2013)

Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa)
, Bioorganic and Medicinal Chemistry 22(7): 2261-2268 (2014)

Design and synthesis of copper-cobalt catalysts for the selective conversion of synthesis gas to ethanol and higher alcohols
, Angewandte Chemie 53(25): 6397-6401 (2014)

Design and synthesis of coumarin-3-acylamino derivatives to scavenge radicals and to protect DNA
, European Journal of Medicinal Chemistry 84: 1-7 (2014)

Design and synthesis of coumarin-based Zn(2+) probes for ratiometric fluorescence imaging
, Inorganic Chemistry 48(16): 7630-7638 (2009)

Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease
, Journal of the American Chemical Society 135(44): 16397-16409 (2013)

Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger
, Angewandte Chemie 52(26): 6633-6637 (2013)

Design and synthesis of cyclic arodyn analogues by ring-closing metathesis (RCM) for kappa opioid receptor (KOP) antagonists
, Advances in Experimental Medicine and Biology 611: 279-280 (2009)

Design and synthesis of cyclic sulfonamides and sulfamates as new calcium sensing receptor agonists
, Bioorganic and Medicinal Chemistry Letters 20(24): 7483-7487 (2010)

Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222
, Chemmedchem 2(10): 1511-1519 (2007)

Design and synthesis of cyclopropylamide analogues of combretastatin-A4 as novel microtubule-stabilizing agents
, Journal of Medicinal Chemistry 56(3): 685-699 (2013)

Design and synthesis of de novo cytotoxic alkaloids by mimicking the bioactive conformation of paclitaxel
, Bioorganic and Medicinal Chemistry 18(19): 7101-7112 (2010)

Design and synthesis of dendritic molecular transporter that achieves efficient in vivo delivery of morpholino antisense oligo
, Bioconjugate Chemistry 19(7): 1464-1470 (2008)

Design and synthesis of dephosphono DNA analogues containing 1,2,3-triazole linker and their UV-melting studies with DNA/RNA
, Nucleosides Nucleotides and Nucleic Acids 31(2): 97-111 (2012)

Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents
, Bioorganic and Medicinal Chemistry Letters 22(19): 6224-6228 (2012)

Design and synthesis of diazatricyclodecane agonists of the G-protein-coupled receptor 119
, Journal of Medicinal Chemistry 56(1): 301-319 (2013)

Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators
, Bioorganic and Medicinal Chemistry Letters 22(8): 2906-2911 (2012)

Design and synthesis of dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole oximes as potent dual inhibitors of TIE-2 and VEGF-R2 receptor tyrosine kinases
, Bioorganic and Medicinal Chemistry Letters 18(6): 1916-1921 (2008)

Design and synthesis of dimethylaminomethyl-substituted curcumin derivatives/analogues: potent antitumor and antioxidant activity, improved stability and aqueous solubility compared with curcumin
, Bioorganic and Medicinal Chemistry Letters 23(5): 1297-1301 (2013)

Design and synthesis of dinucleotide 5'-triphosphates with expanded functionality
, Bioorganic and Medicinal Chemistry 16(20): 9127-9132 (2008)

Design and synthesis of dipeptide mimetics of brain-derived neurotrophic factor
, Bioorganicheskaia Khimiia 38(3): 280-290 (2012)

Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C
, Bioorganic and Medicinal Chemistry Letters 19(18): 5392-5396 (2009)

Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors
, Bioorganic and Medicinal Chemistry Letters 20(13): 3965-3968 (2010)

Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK
, Bioorganic and Medicinal Chemistry Letters 20(24): 7303-7307 (2010)

Design and synthesis of diverse functional kinked nanowire structures for nanoelectronic bioprobes
, Nano Letters 13(2): 746-751 (2013)

Design and synthesis of donor-acceptor Stenhouse adducts: a visible light photoswitch derived from furfural
, Journal of Organic Chemistry 79(23): 11316-11329 (2014)

Design and synthesis of donor-acceptor pyrazabole derivatives for multiphoton absorption
, Dalton Transactions 42(13): 4340-4342 (2013)

Design and synthesis of dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors
, Journal of Medicinal Chemistry 55(23): 10771 (2012)

Design and synthesis of dual-action inhibitors targeting histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme A reductase for cancer treatment
, Journal of Medicinal Chemistry 56(9): 3645-3655 (2013)

Design and synthesis of dual-ligand modified chitosan as a liver targeting vector
, Journal of Materials Science. Materials in Medicine 23(2): 431-441 (2012)

Design and synthesis of dually branched 5'-norcarbocyclic adenosine phosphonodiester analogue as a new anti-HIV prodrug
, Nucleosides Nucleotides and Nucleic Acids 29(10): 721-733 (2010)

Design and synthesis of elastin-like polypeptides for an ideal nerve conduit in peripheral nerve regeneration
, Materials Science and Engineering. C Materials for Biological Applications 38: 119-126 (2014)

Design and synthesis of enantiomeric (R)- and (S)-copper(II) and diorganotin(IV)-based antitumor agents: their in vitro DNA binding profile, cleavage efficiency and cytotoxicity studies
, Journal of Photochemistry and Photobiology. B Biology 136: 62-71 (2014)

Design and synthesis of enediyne-based peptide with selective peptide-cleaving activity
, Chemical Communications 46(13): 2283-2285 (2010)

Design and synthesis of epicocconone analogues with improved fluorescence properties
, Journal of the American Chemical Society 136(43): 15248-15256 (2014)

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy
, Bioorganic and Medicinal Chemistry Letters 22(4): 1793-1796 (2012)

Design and synthesis of fluorescence-labeled closo-dodecaborate lipid: its liposome formation and in vivo imaging targeting of tumors for boron neutron capture therapy
, Organic and Biomolecular Chemistry 10(7): 1374-1380 (2012)

Design and synthesis of fluorescent 7-deazaadenosine nucleosides containing π-extended diarylacetylene motifs
, Organic and Biomolecular Chemistry 13(1): 68-72 (2015)

Design and synthesis of fluorescent SGLT2 inhibitors
, Bioorganic and Medicinal Chemistry Letters 18(18): 4944-4947 (2008)

Design and synthesis of fluorescent pilicides and curlicides: bioactive tools to study bacterial virulence mechanisms
, Chemistry 18(15): 4522-4532 (2012)

Design and synthesis of fluorescent probes for GPR54
, Bioorganic and Medicinal Chemistry 22(13): 3325-3330 (2014)

Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake
, Journal of Medicinal Chemistry 55(5): 2185-2195 (2012)

Design and synthesis of fluoroacylshikonin as an anticancer agent
, Chirality 25(11): 757-762 (2013)

Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents
, Bioorganic and Medicinal Chemistry Letters 22(12): 4018-4022 (2012)

Design and synthesis of glucose-templated proline-lysine chimera: polyfunctional amino acid chimera with high prolyl cis amide rotamer population
, Carbohydrate Research 344(5): 576-585 (2009)

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3
, Bioorganic and Medicinal Chemistry 21(7): 2037-2044 (2013)

Design and synthesis of glycosylated beta3-peptides capable of folding into the 3(14)-helical conformation in water
, Journal of Organic Chemistry 73(14): 5272-5278 (2008)

Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme
, Bioorganic and Medicinal Chemistry Letters 24(2): 613-617 (2014)

Design and synthesis of hairpin probe for specific mis-match discrimination
, Nucleic Acids Symposium Series 2007(51): 311-312 (2007)

Design and synthesis of harzialactone analogues: promising anticancer agents
, Bioorganic and Medicinal Chemistry Letters 20(24): 7243-7245 (2010)

Design and synthesis of heterobimetallic Ru(II)-Ln(III) complexes as chemodosimetric ensembles for the detection of biogenic amine odorants
, Analytical Chemistry 85(17): 8246-8253 (2013)

Design and synthesis of heterobimetallic topoisomerase I and II inhibitor complexes: in vitro DNA binding, interaction with 5'-GMP and 5'-TMP and cleavage studies
, Journal of Photochemistry and Photobiology. B Biology 101(1): 37-46 (2010)

Design and synthesis of heterocyclic cations for specific DNA recognition: from AT-rich to mixed-base-pair DNA sequences
, Journal of Organic Chemistry 79(3): 852-866 (2014)

Design and synthesis of hierarchical MnO2 nanospheres/carbon nanotubes/conducting polymer ternary composite for high performance electrochemical electrodes
, Nano Letters 10(7): 2727-2733 (2010)

Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP)
, Journal of Medicinal Chemistry 57(6): 2773-2788 (2014)

Design and synthesis of high performance multifunctional ultrathin hematite nanoribbons
, Acs Applied Materials and Interfaces 5(22): 11995-12004 (2013)

Design and synthesis of high-affinity dimeric inhibitors targeting the interactions between gephyrin and inhibitory neurotransmitter receptors
, Angewandte Chemie 54(2): 490-494 (2015)

Design and synthesis of high-avidity tetravalent glycoclusters as probes for Sambucus sieboldiana agglutinin and characterization of their binding properties
, Bioconjugate Chemistry 23(1): 97-105 (2012)

Design and synthesis of high-quality CdS/ZnSe type-II core/shell nanocrystals
, Journal of Nanoscience and Nanotechnology 9(10): 5880-5886 (2009)

Design and synthesis of highly luminescent near-infrared-emitting water-soluble CdTe/CdSe/ZnS core/shell/shell quantum dots
, Inorganic Chemistry 48(20): 9723-9731 (2009)

Design and synthesis of highly photostable yellow-green emitting 1,8-naphthalimides as fluorescent sensors for metal cations and protons
, Journal of Fluorescence 19(1): 127-139 (2009)

Design and synthesis of highly potent HIV-1 protease inhibitors with novel isosorbide-derived P2 ligands
, Bioorganic and Medicinal Chemistry Letters 24(11): 2465-2468 (2014)

Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives
, Journal of Medicinal Chemistry 57(23): 10013-10030 (2014)

Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction
, Angewandte Chemie 48(51): 9685-9689 (2009)

Design and synthesis of highly reactive dienophiles for the tetrazine-trans-cyclooctene ligation
, Journal of the American Chemical Society 133(25): 9646-9649 (2011)

Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(9): 2743-2749 (2013)

Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells
, Journal of the American Chemical Society 130(44): 14533-14543 (2008)

Design and synthesis of highly solvatochromic fluorescent 2'-deoxyguanosine and 2'-deoxyadenosine analogs
, Bioorganic and Medicinal Chemistry Letters 21(4): 1275-1278 (2011)

Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid
, Journal of Medicinal Chemistry 57(10): 4058-4072 (2014)

Design and synthesis of hydrolytically stable multivalent ligands bearing thiodigalactoside analogues for peanut lectin and human galectin-3 binding
, Journal of Organic Chemistry 79(14): 6456-6467 (2014)

Design and synthesis of hydroxide ion-conductive metal-organic frameworks based on salt inclusion
, Journal of the American Chemical Society 136(5): 1702-1705 (2014)

Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(16): 4674-4679 (2013)

Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region
, Bioorganic and Medicinal Chemistry Letters 20(20): 6034-6039 (2010)

Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors
, Journal of Agricultural and Food Chemistry 61(27): 6597-6603 (2013)

Design and synthesis of imidazo[1,2-α][1,8]naphthyridine derivatives as anti-HCV agents via direct C-H arylation
, Organic and Biomolecular Chemistry 12(15): 2344-2348 (2014)

Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents
, Chemmedchem 9(12): 2766-2780 (2014)

Design and synthesis of imidazole and triazole derivatives as Lp-PLA₂ inhibitors and the unexpected discovery of highly potent quaternary ammonium salts
, Bioorganic and Medicinal Chemistry Letters 23(5): 1187-1192 (2013)

Design and synthesis of imidazolidine-2,4-dione derivatives as selective inhibitors by targeting protein tyrosine phosphatase-1B over T-cell protein tyrosine phosphatase
, Chemical Biology and Drug Design 82(5): 595-602 (2013)

Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis
, Journal of Medicinal Chemistry 54(7): 2455-2466 (2011)

Design and synthesis of imine compound for metal cation logical gates recognition and setup of double-control fluorescent molecule switch
, Guang Pu Xue Yu Guang Pu Fen Xi 31(7): 1834-1837 (2011)

Design and synthesis of immunoconjugates and development of an indirect ELISA for rapid detection of 3, 5-dinitrosalicyclic Acid hydrazide
, Molecules 13(9): 2238-2248 (2008)

Design and synthesis of immunoconjugates and development of competition inhibition enzyme-linked immunosorbent assay (CIEIA) for the detection of O-isopropyl methylphosphonofluoridate (sarin): an organophosphorous toxicant
, Journal of Hazardous Materials 192(3): 1720-1728 (2011)

Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors
, Bioorganic and Medicinal Chemistry Letters 19(15): 4134-4138 (2009)

Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multidrug resistant protein without COX inhibitory activity
, Journal of Medicinal Chemistry 55(18): 8152-8163 (2012)

Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease
, Journal of Medicinal Chemistry 54(22): 7797-7814 (2011)

Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine
, Organic Letters 11(13): 2824-2827 (2009)

Design and synthesis of inhibitors of Plasmodium falciparum N-myristoyltransferase, a promising target for antimalarial drug discovery
, Journal of Medicinal Chemistry 55(20): 8879-8890 (2012)

Design and synthesis of inhibitors of noroviruses by scaffold hopping
, Bioorganic and Medicinal Chemistry 19(19): 5749-5755 (2011)

Design and synthesis of intrinsically cell-penetrating nucleopeptides
, Organic and Biomolecular Chemistry 6(20): 3661-3663 (2008)

Design and synthesis of iridium bis(carbene) complexes for efficient blue electrophosphorescence
, Chemistry 17(33): 9180-9187 (2011)

Design and synthesis of irreversible inhibitors of foot-and-mouth disease virus 3C protease
, Bioorganic and Medicinal Chemistry Letters 24(2): 490-494 (2014)

Design and synthesis of isocyanide ligands for catalysis: application to Rh-catalyzed hydrosilylation of ketones
, Chemistry An Asian Journal 2(11): 1436-1446 (2007)

Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity
, Bioorganic and Medicinal Chemistry Letters 19(8): 2240-2243 (2009)

Design and synthesis of isonucleosides constructed on a 2-oxa-6-thiabicyclo[3.2.0]heptane scaffold
, Journal of Organic Chemistry 75(12): 4161-4171 (2010)

Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors
, Bioorganic and Medicinal Chemistry Letters 21(8): 2264-2269 (2011)

Design and synthesis of isosteviol triazole conjugates for cancer therapy
, Molecules 19(11): 18676-18689 (2014)

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors
, Bioorganic and Medicinal Chemistry Letters 24(16): 3979-3985 (2014)

Design and synthesis of lamellarin D analogues targeting topoisomerase I
, Journal of Organic Chemistry 74(21): 8143-8153 (2009)

Design and synthesis of laser-activatable tetrazoles for a fast and fluorogenic red-emitting 1,3-dipolar cycloaddition reaction
, Organic Letters 15(21): 5496-5499 (2013)

Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain
, Organic and Biomolecular Chemistry 12(27): 5006-5022 (2014)

Design and synthesis of lipidic organoalkoxysilanes for the self-assembly of liposomal nanohybrid cerasomes with controlled drug release properties
, Chemistry 19(47): 16113-16121 (2013)

Design and synthesis of lipids for the fabrication of functional lipidic cubic-phase biomaterials
, Journal of Organic Chemistry 77(23): 10583-10595 (2012)

Design and synthesis of long acting inhaled corticosteroids for the treatment of asthma
, Bioorganic and Medicinal Chemistry Letters 21(19): 5826-5830 (2011)

Design and synthesis of luminescence chemosensors based on alkynyl phosphine gold(I)-copper(I) aggregates
, Dalton Transactions 40(38): 9703-9710 (2011)

Design and synthesis of lupeol analogues and their glucose uptake stimulatory effect in L6 skeletal muscle cells
, Bioorganic and Medicinal Chemistry Letters 24(12): 2674-2679 (2014)

Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa
, Bioorganic and Medicinal Chemistry Letters 20(23): 6925-6928 (2010)

Design and synthesis of marine fungal phthalide derivatives as PPAR-γ agonists
, Bioorganic and Medicinal Chemistry 20(16): 4954-4961 (2013)

Design and synthesis of marine natural product-based 1H-indole-2,3-dione scaffold as a new antifouling/antibacterial agent against fouling bacteria
, Bioorganic Chemistry 54: 89-95 (2014)

Design and synthesis of medium-ring lactam libraries inspired by octalactin a. A convergent-divergent approach
, Journal of Combinatorial Chemistry 10(5): 628-631 (2008)

Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus
, Bioorganic and Medicinal Chemistry 17(14): 4916-4920 (2009)

Design and synthesis of metal complexes of (2E)-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazinecarbothioamide and their photocatalytic degradation of methylene blue
, Thescientificworldjournal 2013: 828313 (2013)

Design and synthesis of metal sulfide catalysts supported on zeolite nanofiber bundles with unprecedented hydrodesulfurization activities
, Journal of the American Chemical Society 135(31): 11437-11440 (2013)

Design and synthesis of metal-organic frameworks using metal-organic polyhedra as supermolecular building blocks
, Chemical Society Reviews 38(5): 1400-1417 (2009)

Design and synthesis of mimics of the T7-loop of FtsZ
, Organic Letters 15(11): 2700-2703 (2013)

Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling
, Angewandte Chemie 52(33): 8551-8556 (2013)

Design and synthesis of model transparent aqueous colloids with optimal scattering properties
, Langmuir 25(19): 11295 (2009)

Design and synthesis of molecular donors for solution-processed high-efficiency organic solar cells
, Accounts of Chemical Research 47(1): 257-270 (2014)

Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel
, Bioorganic and Medicinal Chemistry Letters 24(11): 2469-2472 (2014)

Design and synthesis of molecularly imprinted polypyrrole based on nanoreactor SBA-15 for recognition of ascorbic acid
, Biosensors and Bioelectronics 39(1): 88-93 (2013)

Design and synthesis of mono and bicyclic tetrapeptides thioester as potent inhibitor of histone deacetylases
, Amino Acids 46(10): 2435-2444 (2014)

Design and synthesis of monofunctionalized, water-soluble conjugated polymers for biosensing and imaging applications
, Journal of the American Chemical Society 133(32): 12600 (2011)

Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
, Bioorganic and Medicinal Chemistry Letters 18(8): 2562-2566 (2008)

Design and synthesis of multifunctional gold nanoparticles bearing tumor-associated glycopeptide antigens as potential cancer vaccines
, Bioconjugate Chemistry 23(8): 1513-1523 (2012)

Design and synthesis of multivalent neoglycoconjugates by click conjugations
, Beilstein Journal of Organic Chemistry 10: 1325-1332 (2014)

Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3
, European Journal of Medicinal Chemistry 46(5): 1622-1629 (2011)

Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(8): 2772-2774 (2012)

Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy
, Journal of Medicinal Chemistry 55(15): 6784-6801 (2012)

Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents
, European Journal of Medicinal Chemistry 54: 512-521 (2012)

Design and synthesis of new 1,3-benzdiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors
, Archiv der Pharmazie 345(4): 257-264 (2012)

Design and synthesis of new 1,3-benzthiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors
, Bioorganic and Medicinal Chemistry 17(15): 5369-5373 (2009)

Design and synthesis of new 1,4-dihydropyridines containing 4(5)-chloro-5(4)-imidazolyl substituent as a novel calcium channel blocker
, Archives of Pharmacal Research 34(9): 1417-1426 (2011)

Design and synthesis of new 1D and 2D R-isophthalic acid-based coordination polymers (R = hydrogen or bromine)
, Chimia 67(6): 393-396 (2013)

Design and synthesis of new 4-pyrazolin-3-yl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolin-1-ylthiazoles as potential antimicrobial agents
, European Journal of Medicinal Chemistry 52: 263-268 (2012)

Design and synthesis of new 7-(N-substituted-methyl)-camptothecin derivatives as potent cytotoxic agents
, Bioorganic and Medicinal Chemistry Letters 24(16): 3850-3853 (2014)

Design and synthesis of new 8-anilide theophylline derivatives as bronchodilators and antibacterial agents
, Archives of Pharmacal Research 35(8): 1355-1368 (2012)

Design and synthesis of new N-(5-trifluoromethyl)-1H-1,2,4-triazol-3-yl benzenesulfonamides as possible antimalarial prototypes
, Molecules 16(9): 8083-8097 (2011)

Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents
, European Journal of Medicinal Chemistry 44(5): 1933-1940 (2009)

Design and synthesis of new N-OMe fluoro-indole melatoninergics
, Medicinal Chemistry ) 3(6): 561-571 (2007)

Design and synthesis of new N1 and C3-substituted 4-fluoroindolic melatoninergics
, Current Drug Discovery Technologies 4(3): 198-207 (2007)

Design and synthesis of new acid cleavable linkers for DNA sequencing by synthesis
, Nucleosides Nucleotides and Nucleic Acids 33(12): 774-785 (2014)

Design and synthesis of new adamantyl-substituted antileishmanial ether phospholipids
, Bioorganic and Medicinal Chemistry Letters 20(18): 5484-5487 (2010)

Design and synthesis of new agents for neuronal nicotinic acetylcholine receptor (nAChRs) imaging
, Nuclear Medicine and Biology 40(1): 126-134 (2013)

Design and synthesis of new amino-modified iminocyclitols: selective inhibitors of alpha-galactosidase
, Organic and Biomolecular Chemistry 8(7): 1527-1530 (2010)

Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect
, Bioorganic and Medicinal Chemistry 18(11): 3860-3874 (2010)

Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives
, Journal of Chemical Information and Modeling 51(12): 3050-3059 (2011)

Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells
, Journal of Medicinal Chemistry 57(16): 6973-6988 (2014)

Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity
, Journal of Medicinal Chemistry 56(6): 2447-2455 (2013)

Design and synthesis of new biprivileged molecular scaffolds: indolo-fused benzodiazepinyl/quinoxalinyl benzimidazoles
, Chemistry An Asian Journal 7(7): 1684-1690 (2012)

Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells
, Molecules 17(9): 10331-10343 (2012)

Design and synthesis of new chiral phosphorus-olefin bidentate ligands and their use in the rhodium-catalyzed asymmetric addition of organoboroxines to N-sulfonyl imines
, Chemical Communications 47(21): 6123-6125 (2011)

Design and synthesis of new cholesterol-conjugated 5-Fluorouracil: a novel potential delivery system for cancer treatment
, Molecules 19(9): 13177-13187 (2014)

Design and synthesis of new cryptophanes with intermediate cavity sizes
, Organic Letters 13(9): 2153-2155 (2011)

Design and synthesis of new fluorescent probe for rapid and highly sensitive detection of proteins via electrophoretic gel stain
, Electrophoresis 32(12): 1403-1413 (2011)

Design and synthesis of new hybrid molecules that activate the transcription factor Nrf2 and simultaneously release carbon monoxide
, Chemistry 20(45): 14698-14704 (2014)

Design and synthesis of new mitomycin dimers containing a seven-membered cyclic disulfide and a diol linkers
, Archives of Pharmacal Research 35(8): 1413-1420 (2012)

Design and synthesis of new of 3-(benzo[d]isoxazol-3-yl)-1-substituted pyrrolidine-2, 5-dione derivatives as anticonvulsants
, European Journal of Medicinal Chemistry 84: 42-50 (2014)

Design and synthesis of new potent anticancer pyrazoles with high FLT3 kinase inhibitory selectivity
, Bioorganic and Medicinal Chemistry 18(11): 3961-3973 (2010)

Design and synthesis of new potent inhibitors of farnesyl pyrophosphate synthase
, Current Drug Discovery Technologies 11(2): 133-144 (2014)

Design and synthesis of new prostaglandin D₂ receptor antagonists
, Bioorganic and Medicinal Chemistry 19(18): 5361-5371 (2011)

Design and synthesis of new rofecoxib analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methanesulfonyl pharmacophore by a N-acetylsulfonamido bioisostere
, Journal of Pharmacy and Pharmaceutical Sciences 10(2): 159-167 (2007)

Design and synthesis of new stabilized combi-triazenes for targeting solid tumors expressing the epidermal growth factor receptor (EGFR) or its closest homologue HER2
, Bioorganic and Medicinal Chemistry Letters 19(18): 5505-5509 (2009)

Design and synthesis of new stable fluorenyl-based radicals
, Journal of the American Chemical Society 136(36): 12784-12793 (2014)

Design and synthesis of new symmetrical derivatives of dihydropyridine containing a pyridyl group on the 3, 5-positions and evaluation of their cytotoxic and multidrug resistance reversal activity
, Journal of Pharmacy and Pharmacology 60(11): 1481-1489 (2008)

Design and synthesis of new tetrahydroquinolines derivatives as CETP inhibitors
, Bioorganic and Medicinal Chemistry Letters 22(11): 3671-3675 (2012)

Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Abeta(1-42) fibrillogenesis and toxicity
, Journal of Peptide Science 15(3): 220-228 (2009)

Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety
, Bioorganic and Medicinal Chemistry 21(2): 412-424 (2013)

Design and synthesis of new vancomycin derivatives
, Bioorganic and Medicinal Chemistry Letters 24(10): 2305-2308 (2014)

Design and synthesis of nitrogen-containing benzoheterocyclic derivatives and their antipsychotic activities
, Yao Xue Xue Bao 44(9): 994-1001 (2009)

Design and synthesis of nitrogen-containing calcined polymer/carbon nanotube hybrids that act as a platinum-free oxygen reduction fuel cell catalyst
, Chemical Communications 47(24): 6843-6845 (2011)

Design and synthesis of non-hydrolyzable homoisoprenoid α-monofluorophosphonate inhibitors of PPAPDC family integral membrane lipid phosphatases
, Bioorganic and Medicinal Chemistry Letters 24(18): 4414-4417 (2015)

Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB
, Organic and Biomolecular Chemistry 8(18): 4066-4070 (2010)

Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C'-diphenylcarborane scaffold as a hydrophobic pharmacophore
, European Journal of Medicinal Chemistry 84: 264-277 (2014)

Design and synthesis of novel 1',3'-dioxolane 5'-deoxyphosphonic acid purine analogues as potent antiviral agents
, Nucleosides Nucleotides and Nucleic Acids 31(2): 85-96 (2012)

Design and synthesis of novel 1,2,3-triazole derivatives of coronopilin as anti-cancer compounds
, European Journal of Medicinal Chemistry 82: 255-262 (2014)

Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents
, European Journal of Medicinal Chemistry 62: 11-19 (2013)

Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents
, European Journal of Medicinal Chemistry 86: 368-380 (2014)

Design and synthesis of novel 1,25-dihydroxyvitamin D3 analogues having a spiro-oxetane fused at the C2 position in the A-ring
, Bioorganic and Medicinal Chemistry 21(17): 5209-5217 (2013)

Design and synthesis of novel 1,4-benzodiazepine derivatives and their biological evaluation as cholinesterase inhibitors
, Archives of Pharmacal Research 35(8): 1369-1377 (2012)

Design and synthesis of novel 2',3'-dideoxy-4'-selenonucleosides as potential antiviral agents
, Bioorganic and Medicinal Chemistry 16(23): 9891-9897 (2008)

Design and synthesis of novel 2'-hydroxy group substituted 2-pyridone derivatives as anticancer agents
, European Journal of Medicinal Chemistry 67: 447-453 (2013)

Design and synthesis of novel 2-(3-substituted propyl)-3-(2-methyl phenyl) quinazolin-4-(3H)-ones as a new class of H1-antihistaminic agents
, Journal of Enzyme Inhibition and Medicinal Chemistry 28(1): 65-71 (2013)

Design and synthesis of novel 2-(4-(2-(dimethylamino)ethyl)-4H-1,2,4-triazol-3-yl)pyridines as potential antitumor agents
, European Journal of Medicinal Chemistry 81: 47-58 (2014)

Design and synthesis of novel 2-methyl-4,5-substitutedbenzo[f]-3,3a,4,5-tetrahydro-pyrazolo[1,5-d][1,4]oxazepin-8(7H)-one derivatives as telomerase inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(3): 720-723 (2013)

Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity
, European Journal of Medicinal Chemistry 80: 167-174 (2014)

Design and synthesis of novel 2-phenylaminopyrimidine (PAP) derivatives and their antiproliferative effects in human chronic myeloid leukemia cells
, Molecules 14(10): 4166-4179 (2009)

Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors
, Bioorganic and Medicinal Chemistry Letters 18(14): 4210-4214 (2008)

Design and synthesis of novel 2H-chromen-2-one derivatives bearing 1,2,3-triazole moiety as lead antimicrobials
, Bioorganic and Medicinal Chemistry Letters 24(7): 1795-1801 (2014)

Design and synthesis of novel 3,4-disubstituted pyrazoles for nanomedicine applications against malignant gliomas
, European Journal of Medicinal Chemistry 45(5): 2024-2033 (2010)

Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors
, Bioorganic and Medicinal Chemistry 21(22): 6893-6909 (2013)

Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors
, Bioorganic and Medicinal Chemistry Letters 23(24): 6711-6716 (2013)

Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands
, Bioorganic and Medicinal Chemistry Letters 18(14): 3919-3924 (2008)

Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers
, Bioorganic and Medicinal Chemistry 21(19): 5936-5944 (2013)

Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity
, European Journal of Medicinal Chemistry 66: 372-379 (2013)

Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents
, European Journal of Medicinal Chemistry 63: 702-712 (2013)

Design and synthesis of novel 5,6-disubstituted pyridine-2,3-dione-3-thiosemicarbazone derivatives as potential anticancer agents
, European Journal of Medicinal Chemistry 81: 22-27 (2014)

Design and synthesis of novel 5-phenyl-N-piperidine ethanone containing 4,5-dihydropyrazole derivatives as potential antitumor agents
, European Journal of Medicinal Chemistry 51: 294-299 (2012)

Design and synthesis of novel 7-aminoquinazoline derivatives: antitumor and anticonvulsant activities
, Bioorganic and Medicinal Chemistry Letters 22(5): 1879-1885 (2012)

Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents
, Journal of Medicinal Chemistry 52(16): 5115-5123 (2009)

Design and synthesis of novel CCR2 antagonists: investigation of non-aryl/heteroaryl binding motifs
, Bioorganic and Medicinal Chemistry Letters 21(6): 1827-1831 (2011)

Design and synthesis of novel D-ring fused steroidal heterocycles
, Steroids 78(12-13): 1200-1208 (2013)

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds
, Journal of Medicinal Chemistry 55(7): 3452-3478 (2012)

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption
, Bioorganic and Medicinal Chemistry 20(15): 4680-4692 (2012)

Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives
, Bioorganic and Medicinal Chemistry 20(18): 5600-5615 (2012)

Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity
, Bioorganic and Medicinal Chemistry 18(11): 3812-3822 (2010)

Design and synthesis of novel N-benzylidenesulfonohydrazide inhibitors of MurC and MurD as potential antibacterial agents
, Molecules 13(1): 11-30 (2008)

Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors
, Journal of Medicinal Chemistry 54(9): 3393-3417 (2011)

Design and synthesis of novel P2 substituents in diol-based HIV protease inhibitors
, European Journal of Medicinal Chemistry 45(1): 160-170 (2010)

Design and synthesis of novel PPARgamma agonists
, Sichuan Da Xue Xue Bao. Yi Xue Ban 41(4): 700-702 (2011)

Design and synthesis of novel SATE derivatives of acyclic isocytosine and 9-deazaadenine C-nucleosides
, Nucleosides Nucleotides and Nucleic Acids 29(3): 257-266 (2010)

Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
, Bioorganic and Medicinal Chemistry Letters 21(6): 1795-1801 (2011)

Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2
, Bioorganic and Medicinal Chemistry Letters 21(18): 5191-5196 (2011)

Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors
, Bioorganic and Medicinal Chemistry 22(14): 3720-3731 (2014)

Design and synthesis of novel anthracene derivatives as n-type emitters for electroluminescent devices: a combined experimental and DFT study
, Photochemical and Photobiological Sciences 13(2): 342-357 (2014)

Design and synthesis of novel antimicrobial acyclic and heterocyclic dyes and their precursors for dyeing and/or textile finishing based on 2-N-acylamino-4,5,6,7-tetrahydro-benzo[b]thiophene systems
, Molecules 16(8): 6271-6305 (2011)

Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis
, Bioorganic and Medicinal Chemistry 21(24): 7830-7840 (2013)

Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter
, Journal of Medicinal Chemistry 54(18): 6305-6318 (2011)

Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells
, Bioorganic and Medicinal Chemistry Letters 24(15): 3361-3365 (2014)

Design and synthesis of novel benzimidazole derivatives as anti-tuberculosis agents
, Yao Xue Xue Bao 49(5): 644-651 (2014)

Design and synthesis of novel benzimidazole derivatives as inhibitors of hepatitis B virus
, Bioorganic and Medicinal Chemistry 18(14): 5048-5055 (2010)

Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition
, Bioorganic and Medicinal Chemistry 21(24): 7612-7623 (2013)

Design and synthesis of novel benzoheterocyclic derivatives as human acrosin inhibitors by scaffold hopping
, European Journal of Medicinal Chemistry 59: 176-182 (2013)

Design and synthesis of novel bis-oximinoalkanoic acids as potent PPAR alpha agonists
, Bioorganic and Medicinal Chemistry Letters 20(3): 1156-1161 (2010)

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition
, Bioorganic and Medicinal Chemistry Letters 22(24): 7345-7350 (2012)

Design and synthesis of novel bone-targeting dual-action pro-drugs for the treatment and reversal of osteoporosis
, Bioorganic and Medicinal Chemistry 20(6): 2131-2140 (2012)

Design and synthesis of novel camptothecin/5-fluorouracil conjugates as cytotoxic agents
, Natural Product Research 25(19): 1817-1826 (2011)

Design and synthesis of novel carbocyclic versions of 2'-spirocyclopropyl ribonucleosides as potent anti-HCV agents
, Nucleosides Nucleotides and Nucleic Acids 30(6): 423-439 (2011)

Design and synthesis of novel cell wall inhibitors of Mycobacterium tuberculosis GlmM and GlmU
, Carbohydrate Research 346(13): 1714-1720 (2011)

Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors
, Bioorganic and Medicinal Chemistry 17(11): 3810-3817 (2009)

Design and synthesis of novel chromenone derivatives as interleukin-5 inhibitors
, Bioorganic and Medicinal Chemistry 21(9): 2543-2550 (2013)

Design and synthesis of novel complexes containing N-phenyl-1H-pyrazole moiety: Ni complex as potential antifungal and antiproliferative compound
, Spectrochimica Acta. Part A Molecular and Biomolecular Spectroscopy 115: 469-475 (2013)

Design and synthesis of novel cyclooxygenase-1 inhibitors as analgesics: 5-amino-2-ethoxy-N-(substituted-phenyl)benzamides
, Chemmedchem 6(3): 550-560 (2011)

Design and synthesis of novel deoxybenzoin derivatives as FabH inhibitors and anti-inflammatory agents
, Bioorganic and Medicinal Chemistry Letters 20(6): 2025-2028 (2010)

Design and synthesis of novel derivatives of all-trans retinoic acid demonstrate the combined importance of acid moiety and conjugated double bonds in its binding to PML-RAR-alpha oncogene in acute promyelocytic leukemia
, Leukemia and Lymphoma 51(6): 1108-1114 (2010)

Design and synthesis of novel diaminoquinazolines with in vivo efficacy for beta-catenin/T-cell transcriptional factor 4 pathway inhibition
, Journal of Medicinal Chemistry 53(2): 897-910 (2010)

Design and synthesis of novel diphenyl oxalamide and diphenyl acetamide derivatives as anticonvulsants
, Archiv der Pharmazie 345(1): 57-64 (2012)

Design and synthesis of novel distamycin-modified nucleoside analogues as HIV-1 reverse transcriptase inhibitors
, Antiviral Research 102: 54-60 (2014)

Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection
, Chemmedchem 6(8): 1390-1400 (2011)

Design and synthesis of novel enhanced water soluble hydroxyethyl analogs of combretastatin A-4
, Bioorganic and Medicinal Chemistry Letters 21(7): 2087-2091 (2011)

Design and synthesis of novel functional lipid-based bioconjugates for drug delivery and other applications
, Methods in Molecular Biology 751: 357-378 (2011)

Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide
, Bioorganic and Medicinal Chemistry Letters 19(23): 6588-6590 (2009)

Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold
, Journal of Medicinal Chemistry 54(23): 8030-8050 (2011)

Design and synthesis of novel hybrid metal complex-DNA conjugates: key building blocks for multimetallic linear DNA nanoarrays
, Organic and Biomolecular Chemistry 7(13): 2729-2737 (2009)

Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity
, Bioorganic and Medicinal Chemistry 18(13): 4625-4629 (2010)