+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Differentiation of benign from malignant thyroid nodules with acoustic radiation force impulse technique



Differentiation of benign from malignant thyroid nodules with acoustic radiation force impulse technique



British Journal of Radiology 87(1035): 20130263



The aim of our study was to assess the performance of acoustic radiation force impulse (ARFI) imaging to differentiate benign from malignant thyroid nodules. 182 patients who needed thyroid surgery were examined. All patients and 50 healthy volunteers underwent ARFI sonoelastography, which quantitatively analysed the elasticity and hardness of the nodule's centre and periphery. ARFI values showed a statistical significance between malignant nodules and benign nodules and common thyroid parenchyma, in both the centre and periphery of nodules (p < 0.01). There was no significant difference between benign nodules and common thyroid parenchyma in either the nodule's centre or periphery (p > 0.05). There was no significant difference between the nodule's centre and periphery of the elastic parameters in both the benign and malignant nodules. There was a statistically significant difference among the two areas (the central group and the peripheral group) under the receiver operating characteristic curve, and the optimal model was the peripheral group. For differentiation of malignant from benign nodules, the sensitivity and specificity were 96.3% and 96.2%, respectively, when 2.545 m s(-1) was chosen as a cut-off value in the peripheral group. ARFI imaging may be helpful to differentiate benign nodules from malignant thyroid nodules. The selecting measurement position is important in ARFI imaging, and it has good diagnostic value in clinical applications. This study shows the diagnostic contribution of ARFI imaging in thyroid lesions.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 052617936

Download citation: RISBibTeXText

PMID: 24588664

DOI: 10.1259/bjr.20130263


Related references

Diagnostic Value of Acoustic Radiation Force Impulse Quantification in the Differentiation of Benign and Malignant Thyroid Nodules. Ultrasonic Imaging 39(5): 326-336, 2017

Acoustic radiation force impulse elastography for differentiation of benign and malignant thyroid nodules with concurrent Hashimoto's thyroiditis. Medical Oncology 32(3): 50, 2015

Acoustic radiation force impulse imaging (ARFI) for differentiation of benign and malignant thyroid nodules--A meta-analysis. European Journal of Radiology 84(11): 2181-2186, 2015

Virtual touch tissue imaging on acoustic radiation force impulse elastography: a new technique for differential diagnosis between benign and malignant thyroid nodules. Journal of Ultrasound in Medicine 33(4): 585-595, 2014

Acoustic Radiation Force Impulse (ARFI) imaging for the distinction between benign and malignant thyroid nodules. La Radiologia Medica 120(6): 579-583, 2015

Comparison of Acoustic Radiation Force Impulse Imaging and Strain Elastography in Differentiating Malignant From Benign Thyroid Nodules. Journal of Ultrasound in Medicine 36(12): 2533-2543, 2017

Preliminary study on the diagnostic value of acoustic radiation force impulse technology for differentiating between benign and malignant thyroid nodules. Journal of Ultrasound in Medicine 31(5): 763-771, 2012

Value of Contrast-Enhanced Ultrasound and Acoustic Radiation Force Impulse Imaging for the Differential Diagnosis of Benign and Malignant Thyroid Nodules. Frontiers in Pharmacology 9: 1363, 2018

Differentiation of benign from malignant liver masses with Acoustic Radiation Force Impulse technique. Ultrasound Quarterly 27(4): 217-223, 2011

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis. Ultrasound in Medicine and Biology 41(12): 3035-3043, 2015

Acoustic radiation force impulse imaging for differentiation of thyroid nodules. Plos one 7(8): E42735, 2012

Clinical efficacy of novel elastography using acoustic radiation force impulse (ARFI) for diagnosis of malignant thyroid nodules. Laryngoscope Investigative Otolaryngology 3(4): 319-325, 2018

The role of acoustic radiation force impulse elastography in the differentiation of benign and malignant focal liver masses. Turkish Journal of Gastroenterology 29(4): 456-463, 2018

Acoustic radiation force impulse elastography for differentiation of malignant and benign breast lesions: a meta-analysis. International Journal of Clinical and Experimental Medicine 8(4): 4753-4761, 2015

Prospective evaluation of acoustic radiation force impulse technology in the differentiation of thyroid nodules: accuracy and interobserver variability assessment. Journal of Ultrasound 17(1): 13-20, 2014