+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Effect of hCG administration during corpus luteum establishment on subsequent corpus luteum development and circulating progesterone concentrations in beef heifers



Effect of hCG administration during corpus luteum establishment on subsequent corpus luteum development and circulating progesterone concentrations in beef heifers



Reproduction, Fertility, and Development 26(3): 367-374



This study examined the effect of a single administration of human chorionic gonadotrophin (hCG) on Day 1 to 4 after oestrus on corpus luteum (CL) development and circulating progesterone (P4). Oestrus-synchronized heifers (n=43) were administered a single intramuscular injection of saline on Day 1 (control) or 3000IU hCG on Day 1, 2, 3 or 4 after oestrus. Administration of hCG on Day 1 had no effect on CL area, on Day 2 increased CL area from Day 6 to 12 (P<0.05), on Day 3 increased CL area from Day 9 to 11, while on Day 4 increased CL size on Days 9 and 10 (P<0.05). Administration of hCG on Day 4 induced the formation of an accessory CL in 89% of heifers, resulting in a significant increase in total luteal tissue area on the ovaries compared with all other groups. Consistent with the effects on the CL, hCG on Day 1 did not affect P4 concentrations, on Day 2 significantly increased P4 compared with the control from Day 6 to 11 (P<0.05), on Day 3 resulted in a non-significant increase in P4 while hCG on Day 4 increased P4 from Day 8 to 13 compared with the control (P<0.05). In conclusion, administration of hCG as early as Day 2 after oestrus results in increased P4 in circulation from Day 6, which should have beneficial downstream effects in terms of uterine receptivity and conceptus elongation.

(PDF emailed within 0-6 h: $19.90)

Accession: 052809462

Download citation: RISBibTeXText

PMID: 23458081

DOI: 10.1071/RD12353


Related references

Establishment of critical timing of progesterone supplementation on corpus luteum and embryo development in beef heifers. Animal Reproduction Science 180: 1-9, 2017

Effect of follicular aspiration just before ovulation on corpus luteum characteristics, circulating progesterone concentrations and uterine receptivity in single-ovulating and superstimulated heifers. Reproduction 143(5): 673-682, 2012

Effect of combined exogenous progesterone with luteotrophic support via equine chorionic gonadotrophin (eCG) on corpus luteum development, circulating progesterone concentrations and embryo development in cattle. Reproduction, Fertility, and Development 28(3): 269-277, 2017

The relationship between embryo viability, corpus luteum development and the early plasma progesterone rise in beef heifers. Journal of Reproduction & Fertility Abstract Series (25): 93, 2000

The effect of a sustained-release injection of human chorionic gonadotropin on corpus luteum formation and progesterone secretion in beef heifers. Drug Development and Industrial Pharmacy 22(2): 97-101, 1996

Volume of luteal tissue and concentration of serum progesterone in cows bearing homogeneous corpus luteum or corpus luteum with cavity. Animal Reproduction Science 49(2-3): 77-82, 1998

Effects of HCG stimulation in cattle with a cystic or compact corpus luteum: progesterone profile, ovulation induction and information of a second corpus luteum. Tierarztliche Umschau 43(7): 430...439, 1988

A biochemical investigation into the function of corpus luteum A study of blood sugar and non-protein nitrogen changes in rabbits after the administration of corpus luteum. Amer Jour Physiol: 586-596, 1930

Effect of dietary omega-3 polyunsaturated fatty acid supplementation on hormone and metabolite concentrations and corpus luteum size in beef heifers. Poultry Science 86: 526-526, 2007

Conception rate in synchronized beef heifers relative to presence of a corpus luteum at progestin administration. Journal of Animal Science 73(SUPPL 1): 242, 1995

Relationships between follicle and corpus luteum diameter, blood flow, and progesterone production in beef cows and heifers: preliminary results. Animal Reproduction 13(2): 81-92, 2016

Effect of stilboestrol injected at the corpus luteum stage in the sow, with special reference to the long maintenance of corpus luteum. Bull. nat. Inst. agric. Sci, Chiba, 14, 1-13, 1958

Ability of human corpus luteum to produce prostaglandins and their effects on progesterone production of human corpus luteum. Nihon Sanka Fujinka Gakkai Zasshi 39(7): 1149-1150, 1987

Effect of exogenous progesterone administration on luteal sensitivity to PGF during the early development of the corpus luteum in mares and cows. Reproduction in Domestic Animals 52(6): 1074-1080, 2017

Effect of dietary monensin upon corpus luteum development in response to exogenous porcine follicle stimulating hormone in sexually mature beef heifers. Journal of Animal Science 51(SUPPL 1): 318, 1980