EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer



Endoscopic submucosal dissection vs endoscopic mucosal resection for superficial esophageal cancer



World Journal of Gastroenterology 20(18): 5540-5547



To investigate the effectiveness of endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) in treating superficial esophageal cancer (SEC). Studies investigating the safety and efficacy of ESD and EMR for SEC were searched from the databases of Pubmed, Web of Science, EMBASE and the Cochrane Library. Primary end points included the en bloc resection rate and the curative resection rate. Secondary end points included operative time, rates of perforation, postoperative esophageal stricture, bleeding and local recurrence. The random-effect model and the fixed-effect model were used for statistical analysis. Eight studies were identified and included in the meta-analysis. As shown by the pooled analysis, ESD had significantly higher en bloc and curative resection rates than EMR. Local recurrence rate in the ESD group was remarkably lower than that in the EMR group. However, operative time and perforation rate for ESD were significantly higher than those for EMR. As for the rate of postoperative esophageal stricture and procedure-related bleeding, no significant difference was found between the two techniques. ESD seems superior to EMR in the treatment of SEC as evidenced by significantly higher en bloc and curative resection rates and by obviously lower local recurrence rate.

(PDF emailed within 0-6 h: $19.90)

Accession: 052967567

Download citation: RISBibTeXText

PMID: 24833885

DOI: 10.3748/wjg.v20.i18.5540



Related references

Endoscopic resection (endoscopic submucosal dissection/endoscopic mucosal resection) for superficial Barrett's esophageal cancer. Digestive Endoscopy 25 Suppl 1: 20-28, 2013

Endoscopic resection (endoscopic mucosal resection/ endoscopic submucosal dissection) for superficial esophageal squamous cell carcinoma: current status of various techniques. Digestive Endoscopy 25 Suppl 1: 13-19, 2013

Endoscopic mucosal resection using a cap-fitted panendoscope and endoscopic submucosal dissection as optimal endoscopic procedures for superficial esophageal carcinoma. Surgical Endoscopy 25(8): 2541-2546, 2011

Endoscopic Piecemeal Mucosal Resection Versus Endoscopic Submucosal Dissection for Superficial Esophageal Lesions Larger Than 15 mm. Clinical Gastroenterology and Hepatology 12(1): 162-163, 2014

Su1489 Comparison of Endoscopic Piecemeal Mucosal Resection (EPMR) and Endoscopic Submucosal Dissection (ESD) for Superficial Esophageal Lesion Larger Than 15 mm. Gastrointestinal Endoscopy 77(5): Ab343-Ab344, 2013

Outcomes of endoscopic submucosal dissection versus endoscopic mucosal resection in management of superficial squamous esophageal neoplasms outside Japan. Journal of Clinical Gastroenterology 44(9): E190-E194, 2011

Clinical outcomes of endoscopic mucosal resection and endoscopic submucosal dissection as a transoral treatment for superficial pharyngeal cancer. Head & Neck 35(9): 1248-1254, 2014

Management of complications associated with endoscopic submucosal dissection/ endoscopic mucosal resection for esophageal cancer. Digestive Endoscopy 25 Suppl 1: 29-38, 2013

Endoscopic submucosal dissection and endoscopic mucosal resection for early stage esophageal cancer. Annals of Cardiothoracic Surgery 6(2): 88-98, 2017

Endoscopic mucosal resection and endoscopic submucosal dissection for en bloc resection of superficial pharyngeal carcinomas. Endoscopy 44(6): 556-564, 2012

Endoscopic Submucosal Dissection and Endoscopic Mucosal Resection for Non-Ampullary Superficial Duodenal Tumor. Digestion 95(1): 36-42, 2017

Endoscopic treatment of large colorectal tumors: comparison of endoscopic mucosal resection, endoscopic mucosal resection-precutting, and endoscopic submucosal dissection. Surgical Endoscopy 26(8): 2220-2230, 2012

Endoscopic submucosal dissection versus endoscopic mucosal resection for type 0-II superficial gastric lesions larger than 20 mm. Annals of Gastroenterology 31(3): 338-343, 2018

Efficacy of endoscopic submucosal dissection for residual or recurrent superficial colorectal tumors after endoscopic mucosal resection. Journal of Digestive Diseases 16(1): 14-21, 2015

Endoscopic treatment of early gastric cancer: from Endoscopic Mucosal Resection (EMR) to Endoscopic Submucosal Dissection (ESD). Revista de Gastroenterologia del Peru 25(1): 76-92, 2005