+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Epidemiological, demographic, and molecular characteristics of laboratory-confirmed pandemic influenza A (H1N1) virus infection in Turkey, May 15-November 30, 2009



Epidemiological, demographic, and molecular characteristics of laboratory-confirmed pandemic influenza A (H1N1) virus infection in Turkey, May 15-November 30, 2009



Japanese Journal of Infectious Diseases 63(4): 239-245



A total of 19,973 clinical specimens obtained from suspected cases of pandemic influenza A virus infection were analyzed by real-time reverse transcription-polymerase chain reaction. Mutations in hemagglutinin (HA) gene and alteration at position 275 in neuraminidase (NA) gene of the randomly selected 29 isolates were detected by sequencing analysis. The virus RNA was detected in 47.3% of the clinical specimens. The pandemic flu cases increased from the 42nd week and peaked in the 46th week of 2009. This intensity continued to the end of the study period. Pandemic flu mainly affected children in the 5-14 year age group, without any gender predominance. The analyzed strains had >98.9% homology with vaccine strains and with each other. More than 37% of the isolates had mutation at position D222E/N on HA gene. There was no isolate harbored mutation at the position H275Y of the NA gene, indicating that the virus isolates currently circulating in Turkey are sensitive to oseltamivir.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 053007304

Download citation: RISBibTeXText

PMID: 20657062


Related references

Case-based reported mortality associated with laboratory-confirmed influenza A(H1N1) 2009 virus infection in the Netherlands: the 2009-2010 pandemic season versus the 2010-2011 influenza season. Bmc Public Health 11: 758, 2012

A prospective comparison of the epidemiological and clinical characteristics of pandemic (H1N1) 2009 influenza A virus and seasonal influenza A viruses in Guangzhou, South China in 2009. Japanese Journal of Infectious Diseases 65(3): 208-214, 2012

Using surveillance data to estimate pandemic vaccine effectiveness against laboratory confirmed influenza A(H1N1)2009 infection: two case-control studies, Spain, season 2009-2010. Bmc Public Health 11: 899, 2012

Serologically confirmed household transmission of 2009 pandemic influenza A (H1N1) virus during the first pandemic wave--New York City, April-May 2009. Clinical Infectious Diseases 53(5): 455-462, 2011

Epidemiological characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection. Medical Journal of Australia 191(3): 146-149, 2009

Prevalence and clinical features of pneumonia in patients with laboratory-confirmed pandemic influenza A H1N1 2009 infection in South Korea. Scandinavian Journal of Infectious Diseases 43(1): 19-26, 2011

Pandemic influenza H1N1 2009 virus infection in pregnancy in Turkey. Taiwanese Journal of Obstetrics and Gynecology 50(3): 312-317, 2011

Molecular and serological investigations of the Influenza A(H1N1) 2009 pandemic virus in Turkey. Medical Microbiology and Immunology 202(4): 277-284, 2013

Influenza A (H1N1) pandemic in Iran: report of first confirmed cases from June to November 2009. Archives of Iranian Medicine 13(2): 91-98, 2010

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections. Clinical Infectious Diseases 51(9): 1033-1041, 2010

Clinico-epidemiological features of the hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in Saurashtra region, India (September, 2009 to February, 2010). Lung India 28(1): 11-16, 2011

Prevalence of Oseltamivir-Resistant 2009 H1N1 Influenza Virus among Patients with Pandemic 2009 H1N1 Influenza infection in NRITLD, Tehran, Iran. Tanaffos 10(1): 8, 2011

Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: experience from multiple tertiary paediatric centres in Turkey. Scandinavian Journal of Infectious Diseases 43(11-12): 923-929, 2011

Clinical and molecular characteristics of the 2009 pandemic influenza H1N1 infection with severe or fatal disease from 2009 to 2011 in Shenzhen, China. Journal of Medical Virology 85(3): 405-412, 2013

Genetic and molecular characteristics of the 2009 H1N1 pandemic influenza A virus. Nihon Rinsho. Japanese Journal of Clinical Medicine 68(9): 1590-1593, 2010