Section 54
Chapter 53,061

Evaluation of BACTEC MGIT 960 system for the second-line drugs susceptibility testing of Mycobacterium tuberculosis in China

Zhao, L.-l.; Xia, Q.; Lin, N.; Liu, B.; Zhao, X.-q.; Liu, Z.; Wan, K.-l.

Journal of Microbiological Methods 91(1): 212-214


ISSN/ISBN: 1872-8359
PMID: 22766324
DOI: 10.1016/j.mimet.2012.06.010
Accession: 053060583

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When the performance of the BACTEC MGIT 960 system was evaluated with the traditional proportion method (PM) on 321 clinical isolates of Mycobacterium tuberculosis from China, concordance values were 98.44% capreomycin, 98.75% kanamycin, 98.75% ofloxacin and 94.08% ethionamide. The turnaround time with BACTEC MGIT 960 system (7.5±1.8 days) was significantly shorter than with PM (28 days or 42 days). Therefore, the BACTEC MGIT 960 system was a reliable and rapid method for second-line drug susceptibility testing of TB in China.

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