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Evaluation of the VersaTREK system compared to the Bactec MGIT 960 system for first-line drug susceptibility testing of Mycobacterium tuberculosis

Espasa, M.; Salvadó, M.; Vicente, E.; Tudó, G.; Alcaide, F.; Coll, P.; Martin-Casabona, N.; Torra, M.; Fontanals, D.; González-Martín, J.

Journal of Clinical Microbiology 50(2): 488-491

2012


ISSN/ISBN: 1098-660X
PMID: 22135258
DOI: 10.1128/jcm.06432-11
Accession: 053082937

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The aim of this study was to evaluate the reliability of the VersaTREK system for Mycobacterium tuberculosis drug susceptibility testing compared with results obtained with the Bactec MGIT 960 system. A total of 67 strains were evaluated. Overall agreement was at 98.5%. Kappa indexes were 1.0 for isoniazid, rifampin, and ethambutol, 0.937 for pyrazinamide, and 0.907 for streptomycin. The VersaTREK system is validated for M. tuberculosis drug susceptibility testing.

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