+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Evaluation of the prognostic value of the metastatic lymph node ratio for gastric cancer



Evaluation of the prognostic value of the metastatic lymph node ratio for gastric cancer



American Journal of Surgery 207(4): 555-565



The aim of this study was to investigate the prognostic value of metastatic lymph node (LN) ratio (LNR) compared with pathologic node (pN) category. Three hundred ninety-nine patients with gastric cancer with R0 resection were reviewed. LNR, pN, and the number of retrieved LNs were evaluated in node-positive groups with ≥15 or <15 LNs resected and a node-negative group, respectively, by univariate and multivariate analyses. Associations of pN and LNR with the number of retrieved LNs were determined using Spearman's rank correlation test. LNR and pN were correlated with overall survival. For the node-positive group with ≥15 LNs retrieved, pN and LNR were independent prognostic factors, with the hazard ratio higher for LNR; neither was correlated with the number of retrieved LNs. For the group with <15 LNs retrieved, LNR but not pN was an independent prognostic factor, with LNR uncorrelated with the number of LNs retrieved. For the node-negative group, the number of LNs retrieved retained an independent prognostic factor. LNR is an independent prognostic factor in node-positive patients with gastric cancer with R0 resection, and it is uninfluenced by the number of LNs retrieved. It may be superior to pN.

(PDF emailed within 0-6 h: $19.90)

Accession: 053087195

Download citation: RISBibTeXText

PMID: 24124661

DOI: 10.1016/j.amjsurg.2013.05.004


Related references

Metastatic lymph node ratio versus number of metastatic lymph nodes as a prognostic factor in gastric cancer. European Journal of Surgical Oncology 38(6): 497-502, 2012

Prognostic significance of metastatic lymph node ratio in patients with gastric cancer: an evaluation in north-East of iran. Iranian Journal of Cancer Prevention 7(2): 73-79, 2014

Prognostic value of metastatic lymph node ratio for gastric cancer patients with less than 15 lymph nodes dissection. Zhonghua Wei Chang Wai Ke Za Zhi 16(2): 151-154, 2014

Prognostic value of metastatic lymph node ratio in gastric cancer. Zhonghua Wei Chang Wai Ke Za Zhi 15(2): 137-140, 2014

Prognostic significance of metastatic lymph node ratio in T3 gastric cancer. World Journal of Surgery 26(3): 323-329, 2002

Metastatic lymph node ratio as a prognostic factor in gastric cancer. European Journal of Surgical Oncology 31(1): 59-66, 2005

Prognostic value of metastatic lymph node ratio for patients with gastric cancer. Zhonghua Wei Chang Wai Ke Za Zhi 14(7): 516-519, 2013

Prognostic Impact of the Metastatic Lymph Node Ratio on Survival in Gastric Cancer. Indian Journal of Surgical Oncology 7(1): 67-72, 2016

Metastatic lymph node ratio is an independent prognostic factor in gastric cancer. Hepato-Gastroenterology 56(91-92): 908-913, 2009

Prognostic significance of the metastatic lymph node ratio in patients with gastric cancer. World Journal of Surgery 36(5): 1096-1101, 2012

Prognostic significance of the metastatic lymph node ratio in gastric cancer patients. World Journal of Surgery 33(11): 2378-2382, 2010

Prognostic impact of metastatic lymph node ratio in advanced gastric cancer from cardia and fundus. World Journal of Gastroenterology 14(27): 4383-4388, 2008

Prognostic value of metastatic lymph node ratio in gastric cancer patients undergoing radical gastrectomy. Zhonghua Wei Chang Wai Ke Za Zhi 16(1): 56-59, 2014

Prognostic value of metastatic lymph node ratio as an additional tool to the TNM stage system in gastric cancer. European Journal of Surgical Oncology 41(7): 927-933, 2015

Prognostic impact of metastatic lymph node ratio on gastric cancer after curative distal gastrectomy. World Journal of Gastroenterology 16(16): 2055-2060, 2010