Section 54
Chapter 53,218

Fatty acid synthase and prostate cancer

Wang, K.-F.; Wu, B.

Zhonghua Nan Ke Xue 14(8): 740-742


ISSN/ISBN: 1009-3591
PMID: 18817351
Accession: 053217027

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The over expression of fatty acid synthase (FAS), a key enzyme in biosynthesis of fatty acid, can enhance enzyme activity and result in the malignant behavior, special material metabolism and energy metabolism of tumors. The expression of FAS is significantly higher in prostate cancer than in normal prostate tissues, which shows that FAS can be used as a marker in the early diagnosis of prostate cancer. The abnormally increased expression of FAS in prostate cancer may offer a new target for the drug treatment of the disease.

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