EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

HIV-associated Kaposi sarcoma in African children


Sadj 65(1): 20-22
HIV-associated Kaposi sarcoma in African children
HIV-associated Kaposi sarcoma (HIV-KS) is common in African countries where HIV infection is pandemic and anti-retroviral medication is not readily available. Human herpesvirus-8 (HHV-8), which is the essential, but not the sole aetiological factor in KS, is endemic in sub-Saharan Africa and is substantially more prevalent in HIV-seropositive than in HIV-seronegative subjects. In children in sub-Saharan Africa, KS, whether it be HIV-KS or African endemic KS is much more prevalent than any other epidemiological forms of KS. In addition, in sub-Saharan children oral KS is common, and the life-expectancy of HIV-seropositive children with KS is short. Since generalized systemic KS is frequently associated with oral HIV-KS, it is advisable to introduce systemic cytotoxic chemotherapy early in the course of oral HIV-KS. Although the introduction of highly active antiretroviral therapy (HAART) brought about a decline in the incidence of HIV-KS worldwide, HIV-KS remains a significant problem in sub-Saharan Africa where the prevalence of HHV-8 infection is high and access to HAART is limited.

(PDF 0-2 workdays service: $29.90)

Accession: 053466091

PMID: 20411798



Related references

Human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) DNA in Kaposi's sarcoma lesions, AIDS Kaposi's sarcoma cell lines, endothelial Kaposi's sarcoma simulators, and the skin of immunosuppressed patients. American Journal of Pathology 148(6): 2009-2016, 1996

Kaposi sarcoma in African children. Annals of the Royal College of Surgeons of England 54(6): 270-271, 1974

Kaposi's sarcoma in African children. Acta - Unio Internationalis Contra Cancrum 18: 394-399, 1962

Kaposi sarcoma in South African children. Pediatric Blood & Cancer 56(3): 392-396, 2011

Kaposi's sarcoma in East African children: a report of 51 cases. Journal of Pathology 100(3): 187-199, 1970

Transmission of Kaposi sarcoma-associated herpesvirus between mothers and children in a South African population. Journal of Acquired Immune Deficiency Syndromes 44(3): 351-355, 2007

Children with kaposi sarcoma in two southern african hospitals: clinical presentation, management, and outcome. Journal of Tropical Medicine 2013: 213490-213490, 2014

Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group. Archives of Internal Medicine 156(2): 202-204, 1996

Pseudo-Kaposi Sarcoma or Kaposi Sarcoma? Kaposi-sarcoma-like skin lesions in a patient with AIDS. Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und Verwandte Gebiete 59(3): 233-236, 2007

Kaposi sarcoma-associated herpesvirus (KSHV) seroprevalence in population-based samples of African children: evidence for at least 2 patterns of KSHV transmission. Journal of Infectious Diseases 200(3): 430-438, 2009