+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Hemodynamic effects of positive end-expiratory pressure during abdominal hyperpression: a preliminary study in healthy volunteers



Hemodynamic effects of positive end-expiratory pressure during abdominal hyperpression: a preliminary study in healthy volunteers



Journal of Critical Care 27(1): 33-36



An increase in abdominal pressure induces an increase in left ventricular afterload under clinical conditions. We tested the hypothesis that positive end-expiratory pressure (PEEP) could reverse the hemodynamic consequences of abdominal hyperpression by opposing the increase in left ventricular afterload. Eight healthy volunteers were investigated during 3 experimental conditions: (1) baseline, (2) increase in abdominal pressure by means of medical antishock trousers (MAST) inflation, and (3) addition of PEEP +10 cm H(2)O. Heart loading conditions and left ventricular systolic and diastolic function were assessed by transthoracic echocardiography. The application of PEEP significantly reduced the prior increase in end-systolic wall stress: 45 ± 11 vs 55 ± 14 kdyn/cm(2), P < .05. Medical antishock trousers inflation significantly altered the deceleration time of mitral E wave: 199 ± 23 vs 156 ± 38 milliseconds, P < .05. Left ventricular preload and global systolic performance were unaffected by MAST and PEEP applications. The increase in left ventricular afterload induced by MAST inflation can be efficiently reduced by the use of a moderate PEEP. Potential clinical applications in the abdominal compartment syndrome or in the setting of laparoscopic surgery should be developed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 053509607

Download citation: RISBibTeXText

PMID: 21514092

DOI: 10.1016/j.jcrc.2011.03.003


Related references

Non-invasive positive-pressure ventilation with positive end-expiratory pressure counteracts inward air leaks during preoxygenation: a randomised crossover controlled study in healthy volunteers. British Journal of Anaesthesia 120(4): 868-873, 2018

Respiratory and hemodynamic effects of positive end-expiratory pressure (PEEP) with increased intra-abdominal pressure. Masui. Japanese Journal of Anesthesiology 36(2): 179-187, 1987

Comparison of the hemodynamic effects of gasless abdominal distention and CO2 pneumoperitoneum during incremental positive end-expiratory pressure. Journal of Surgical Research 58(1): 75-80, 1995

The influence of changes in blood volume on the hemodynamic effects of positive end expiratory pressure positive end expiratory pressure. European Journal of Clinical Investigation 8(5): 338, 1978

Hemodynamic effects of positive end expiratory pressure ventilation transesophageal echocardiographic study. European Heart Journal 6(ABSTR SUPPL 1): 125, 1985

Hemodynamic effects of continuous positive airway pressure and positive end expiratory pressure during 1 lung anesthesia with isoflurane. Anesthesiology (Hagerstown) 61(3 PART A): A520, 1984

Comparison of Intra-Abdominal Pressure Among 3 Prone Positional Apparatuses After Changing From the Supine to the Prone Position and Applying Positive End-Expiratory Pressure in Healthy Euvolemic Patients: A Prospective Observational Study. Journal of Neurosurgical Anesthesiology 29(1): 14-20, 2015

Cardiopulmonary effects of matching positive end-expiratory pressure to abdominal pressure in concomitant abdominal hypertension and acute lung injury. Journal of Trauma 69(2): 375-383, 2010

Cardiopulmonary Effects of Matching Positive End-Expiratory Pressure to Abdominal Pressure in Concomitant Abdominal Hypertension and Acute Lung Injury. Yearbook of Critical Care Medicine 2011: 7-8, 2011

Hemodynamic effects of positive end-expiratory pressure. Giornale Italiano di Cardiologia 18(6): 505-512, 2017

The hemodynamic effects of positive end-expiratory pressure. Anesthesiology 64(1): 130-132, 1986

Matching positive end-expiratory pressure to intra-abdominal pressure prevents end-expiratory lung volume decline in a pig model of intra-abdominal hypertension. Critical Care Medicine 40(6): 1879-1886, 2012

Hemodynamic effects of intermittent positive pressure ventilation and high-frequency jet ventilation with positive end-expiratory pressure in lung-lavaged dogs. Chung-Ang Journal of Medicine 18(4): 445-456, 1993

Hemodynamic effects of continuous positive-pressure ventilation and high-frequency jet ventilation with positive end-expiratory pressure in normal dogs. Critical Care Medicine 12(9): 750-754, 1984

Hemodynamic effects of positive end-expiratory pressure. Historical perspective. American Journal of Medicine 81(2): 307-310, 1986