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In vitro and in vivo model systems to study microbial biofilm formation



In vitro and in vivo model systems to study microbial biofilm formation



Journal of Microbiological Methods 83(2): 89-105



Biofilm formation is often considered the underlying reason why treatment with an antimicrobial agent fails and as an estimated 65-80% of all human infections is thought to be biofilm-related, this presents a serious challenge. Biofilm model systems are essential to gain a better understanding of the mechanisms involved in biofilm formation and resistance. In this review a comprehensive overview of various in vitro and in vivo systems is presented, and their advantages and disadvantages are discussed.

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Accession: 053770204

Download citation: RISBibTeXText

PMID: 20816706

DOI: 10.1016/j.mimet.2010.08.018


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