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Ineffectiveness of myrrh-derivative Mirazid against schistosomiasis and fascioliasis in humans



Ineffectiveness of myrrh-derivative Mirazid against schistosomiasis and fascioliasis in humans



Eastern Mediterranean Health Journal 16(9): 932-936



The present study assessed the schistosomicidal and fasciolicidal actions of the myrrh-derivative Mirazid in an area of low schistosomiasis transmission. A total of 27 patients infected with Schistosoma mansoni and 16 with Fasciola spp. received the maximum recommended dose of Mirazid. Pretreatment egg counts in 4 Kato-Katz slides were compared with similar counts in stool samples collected 1 and 2 months after treatment. Standard procedures and quality control measures were followed. The results revealed that Mirazid used as schistosomicidal or fasciolicidal agent in the maximum recommended dose has a low cure rate and produced a negligible reduction in egg counts. Prescribing such an ineffective drug in Egypt might endanger the achievements of the schistosomiasis control strategy.

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Accession: 053824343

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PMID: 21218718


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