+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Infectious dental diseases in patients with coronary artery disease: an orthopantomographic case-control study



Infectious dental diseases in patients with coronary artery disease: an orthopantomographic case-control study



Journal 75(1): 35



To investigate a potential association between coronary artery disease (CAD) and a variety of radiographically detectable infectious dental diseases, a hospital-based prospective case-control study was conducted in Kuwait. Eighty-eight consecutive patients with a first attack of unstable angina pectoris or acute myocardial infarction were enrolled as cases and were matched on the basis of age, sex and nationality with control patients who were known not to have CAD. The severity and extent of periodontal bone loss and other radiographic signs of infection in both cases and controls were analyzed with orthopantomograms. More cases than controls had teeth needing extraction (p = 0.043), periapical lesions (p = 0.028), molars with furcation lesions (p < 0.001), teeth with marginal bone loss > or = 6 mm (p = 0.001) and teeth with angular (vertical) bone loss (p < 0.001). Analysis of the total dental index showed that the median scores were higher for cases than controls for both radiographically diagnosed periodontitis (p < 0.001) and periapical lesions (p = 0.008). In summary, there was a significant association between radiographically diagnosed periodontal diseases and CAD. These results should not be regarded as indicating a causal relationship, especially given that the diagnosis of periodontitis was based only on a radiographic examination. The true impact of oral infections on CAD should be examined in a large prospective clinical and interventional study.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 053829051

Download citation: RISBibTeXText

PMID: 19239740


Related references

Risk factors for severe coronary artery disease - a case-control study of patients who have undergone coronary artery bypass grafting. Journal of Atherosclerosis and Thrombosis 13(1): 62-67, 2006

Improved survival with coronary bypass surgery in patients with severe coronary artery disease a matched case control study in patients with potentially operable disease. Journal of the American College of Cardiology 7(2 Suppl. A): 33A, 1986

The impact of early menopause on risk of coronary artery disease (PREmature Coronary Artery Disease In Women--PRECADIW case-control study). European Journal of Preventive Cardiology 19(1): 95, 2012

Visceral adiposity in young patients with coronary artery disease-a case control study. Indian Heart Journal 64(3): 284-289, 2013

Determinants of coronary artery disease in nondiabetic hemodialysis patients: a matched case-control study. Renal Failure 29(1): 67-71, 2007

Matrix metalloproteinases polymorphisms in patients with aneurysmal coronary artery disease A case/control study. European Heart Journal 22(Abstract Suppl.): 164, 2001

Increased prevalence of psoriasis in patients with coronary artery disease: results from a case-control study. British Journal of Dermatology 171(3): 580-587, 2014

Patients with advanced liver disease are protected from severe coronary artery disease and myocardial infarction. An age matched, autopsy based case control study. 2007

Association of plasma phytosterol concentrations with incident coronary heart disease Data from the CORA study, a case-control study of coronary artery disease in women. Atherosclerosis 203(1): 284-290, 2009

Apical ballooning in patients with coronary artery disease versus takotsubo cardiomyopathy--a case control study. International Journal of Cardiology 166(3): 738-739, 2013

Clearance of chylomicron remnants in normolipidaemic patients with coronary artery disease: case control study over three years. BMJ 312(7036): 935-939, 1996

Coronary artery disease in young age and chronic infection with Helicobacter pylori Case-control study of 55 patients. Gut 47(Suppl. 1): A49, 2000

Prevalence of left main coronary artery disease, of three- or four-vessel coronary artery disease, and of obstructive coronary artery disease in patients with and without peripheral arterial disease undergoing coronary angiography for suspected coronary artery disease. American Journal of Cardiology 92(3): 304-305, 2003

Celecoxib and sulfasalazine had negative association with coronary artery diseases in patients with ankylosing spondylitis: A nation-wide, population-based case-control study. Medicine 95(36): E4792, 2016

Nutritional related cardiovascular risk factors in patients with coronary artery disease in Iran: a case-control study. Nutrition Journal 9: 70, 2010