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Insulin-dependent diabetes mellitus associated with presumed autoimmune polyendocrine syndrome in a mare



Insulin-dependent diabetes mellitus associated with presumed autoimmune polyendocrine syndrome in a mare



Canadian Veterinary Journal 52(5): 506-512



A 5-year-old Thoroughbred-cross mare was diagnosed with insulin-dependent diabetes mellitus. Partial glycemic control and clinical improvement were achieved with daily insulin administration for 18 mo. The mare subsequently developed evidence of hypoadrenocorticism and died. Necropsy findings included lymphocytic infiltration of the pancreas, adrenal cortex, adrenal medulla, and thyroid glands, suggestive of an immune-mediated polyendocrinopathy.

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Accession: 053889317

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PMID: 22043070


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