+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Interaction between essential elements selenium and zinc with cadmium and mercury in samples from hypertensive patients



Interaction between essential elements selenium and zinc with cadmium and mercury in samples from hypertensive patients



Biological Trace Element Research 160(2): 185-196



The abnormal metabolism of metal ions plays an important role in health and disease conditions; hence, the studies about them have received much interest. The objective of this study was to evaluate the association between trace and toxic elements zinc (Zn), cadmium (Cd), selenium (Se), and mercury (Hg) in biological samples (scalp hair, blood, and urine) of hypertensive patients (n = 257), residents of Hyderabad, Pakistan. For comparison purpose, the biological samples of age-matched healthy controls were selected as referents. The concentrations of trace and toxic elements were measured by atomic absorption spectrophotometer prior to microwave-assisted acid digestion. The validity and accuracy of the methodology was checked using certified reference materials and by the conventional wet acid digestion method. The recovery of all studied elements was found in the range of 96.4-99.1 % in certified reference materials. The results of this study showed that the mean values of Cd and Hg were significantly higher in scalp hair, blood, and urine samples of hypertensive patients than in referents (P < 0.001), whilst the concentrations of Zn and Se were lower in the scalp hair and blood, but higher in the urine samples of hypertensive patients. The deficiency of Zn and Se and the high exposure of toxic metals may be synergistic with risk factors associated with hypertension.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 053902285

Download citation: RISBibTeXText

PMID: 24962640

DOI: 10.1007/s12011-014-0048-y


Related references

Determination of essential elements (copper, manganese, selenium and zinc) in fish and shellfish samples. Risk and nutritional assessment and mercury-selenium balance. Food and Chemical Toxicology 62: 299-307, 2013

Genetic effects on toxic and essential elements in humans: arsenic, cadmium, copper, lead, mercury, selenium, and zinc in erythrocytes. Environmental Health Perspectives 118(6): 776-782, 2010

Effect of essential elements zinc, copper, and selenium on placental cadmium transport. Acta Nutrimenta Sinica 26(6): 450-453, 2004

Bioavailability from foods of trace elements: iron, zinc, copper, selenium, chromium, lead, cadmium, mercury. Annali Dell'istituto Superiore di Sanita 20(2-3): 149-169, 1984

Metabolic relationship between some trace elements in the organism cadmium zinc selenium mercury abstract rat blood levels. Ceskoslovenska Fysiologie 17(3): 235-236, 1968

Metabolic interrelations of trace elements the effect of an essential nutrient selenium on the toxicity of mercury and cadmium abstract rat. Proc Int Union Physiol Sci 7(24): 337, 1968

Determination of mercury, cadmium, lead, zinc, selenium and iron by ICP-OES in mushroom samples from around thermal power plant in Muğla, Turkey. Bulletin of Environmental Contamination and Toxicology 87(3): 276-281, 2011

The use of feathers in the study of sources of contamination in birds by trace elements cadmium copper mercury lead selenium and zinc in flamingos from camargue france. Water Air & Soil Pollution 42(1-2): 103-116, 1988

Intake of trace elements and heavy metals by children aged 2-14 years. Zinc, manganese, copper, fluorine, iodine, selenium, lead, cadmium, mercury. Monatsschrift fur Kinderheilkunde 129(4): 233-238, 1981

Detoxification mechanism of heavy metals in marine mammals and seabirds: interaction of selenium with mercury, silver, copper, zinc, and cadmium in liver. Archives of Environmental Contamination and Toxicology 47(3): 402-413, 2004

Biological interaction of ascorbic acid and mineral nutrients Iron, selenium, copper, nickel, manganese, zinc, cobalt, cadmium, mercury, Vitamin C. Advances in chemistry series: 00) 551-569, 1982

Uptake of trace elements by barley in zinc-polluted soils. 2. Lead, cadmium, mercury, selenium, arsenic, chromium, and vanadium in barley. Soil Science 121(1): 38-43, 1976

Studies on the interaction between selenium tellurium cadmium arsenic and zinc and the distribution of iron cobalt rubidium and mercury in mice by instrumental neutron activation analysis. Journal of Radioanalytical & Nuclear Chemistry 109(1): 79-88, 1987

Mercury, selenium, and cadmium in human autopsy samples from Idrija residents and mercury mine workers. Environmental Research 84(3): 211-218, 2000

Alterations in plasma essential trace elements selenium, manganese, zinc, copper, and iron concentrations and the possible role of these elements on oxidative status in patients with childhood asthma. Biological Trace Element Research 97(1): 31-41, 2004