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Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography



Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography



Biomedical Optics Express 1(2): 431-440



Scanning laser ophthalmoscopy (SLO) and spectral domain optical coherence tomography (SDOCT) have become essential clinical diagnostic tools in ophthalmology by allowing for video-rate noninvasive en face and depth-resolved visualization of retinal structure. Current generation multimodal imaging systems that combine both SLO and OCT as a means of image tracking remain complex in their hardware implementations. Here, we combine a spectrally encoded confocal scanning laser ophthalmoscope (SECSLO) with an ophthalmic SDOCT system. This novel implementation of an interlaced SECSLO-SDOCT system allows for video-rate SLO fundus images to be acquired alternately with high-resolution SDOCT B-scans as a means of image aiming, guidance, and registration as well as motion tracking. The system shares the illumination source, detection system, and scanning optics between both SLO and OCT as a method of providing a simple multimodal ophthalmic imaging system that can readily be implemented as a table-top or hand-held device.

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Accession: 053914442

Download citation: RISBibTeXText

PMID: 21258478

DOI: 10.1364/BOE.1.000431


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