+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Intrauterine contraception for adolescents aged 14-18 years: a multicenter randomized pilot study of levonorgestrel-releasing intrauterine system compared to the Copper T 380A



Intrauterine contraception for adolescents aged 14-18 years: a multicenter randomized pilot study of levonorgestrel-releasing intrauterine system compared to the Copper T 380A



Contraception 81(2): 123-127



Intrauterine contraception can provide adolescents with effective, long-term contraception as well as with other health benefits. In adult populations, intrauterine contraception rates highly in patient satisfaction and safety. It is rarely prescribed to adolescents because of limited data. Multicenter, randomized, controlled, participant-blinded pilot study of 14-18-year-old females assigned to the Copper T 380A intrauterine device or the Levonorgestrel Intrauterine System. Participants were followed up for 6 months following insertion. We enrolled 23 participants; 12 received the Levonorgestrel Intrauterine System, and 11 received the Copper T 380A. At 6 months, the continuation rates were 75% for the Levonorgestrel Intrauterine System users and 45% for the Copper T 380A users (p=.15). Two Copper T 380A users experienced partial expulsion. Heavy bleeding and pelvic pain were the most commonly reported side effects. Participants rated both methods favorably. This study shows that at 6 months, though not statistically significant, adolescent continuation rates trended towards being greater with the Levonorgestrel Intrauterine System compared to the Copper T 380A. These pilot data will be helpful in the design of a larger trial of intrauterine contraception use among adolescents.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 053950290

Download citation: RISBibTeXText

PMID: 20103449

DOI: 10.1016/j.contraception.2009.09.004


Related references

Intrauterine contraception for adolescents aged 1418years: a multicenter randomized pilot study of Levonorgestrel-releasing intrauterine system compared to the Copper T 380A. Yearbook of Obstetrics Gynecology and Women's Health 2010: 257-258, 2010

Two years' experience with two levonorgestrel-releasing intrauterine devices and one copper-releasing intrauterine device: a randomized comparative performance study. Fertility and Sterility 39(2): 187-192, 1983

The role of copper-releasing intrauterine device or levonorgestrel-releasing intrauterine system on uterine bleeding and iron status (prospective study of 8 years). Minerva Ginecologica 54(3): 271-278, 2002

Two years of intrauterine contraception with levonorgestrel and with copper a randomized comparison of the copper t 380 silver and levonorgestrel 20 mcg per day devices. Contraception 35(3): 245-256, 1987

Two years of intrauterine contraception with levonorgestrel and with copper: a randomized comparison of the TCu 380Ag and levonorgestrel 20 mcg/day devices. Contraception 35(3): 245-255, 1987

Weight variation in users of depot-medroxyprogesterone acetate, the levonorgestrel-releasing intrauterine system and a copper intrauterine device for up to ten years of use. European Journal of Contraception & Reproductive Health Care 20(1): 57-63, 2015

Acceptability of the levonorgestrel-releasing intrauterine system after discontinuation of previous contraception: Results of a French clinical study in women aged 35 to 45 years. Contraception 66(2): 121-128, 2002

Protective effect of intrauterine release of levonorgestrel on pelvic infection: three years' comparative experience of levonorgestrel- and copper-releasing intrauterine devices. Obstetrics and Gynecology 77(2): 261-264, 1991

Effects of Mirena (levonorgestrel-releasing intrauterine system) and Ortho Gynae T380 intrauterine copper device on lipid metabolism--a randomized comparative study. Contraception 79(1): 24-28, 2009

Sexual functioning in women using levonorgestrel-releasing intrauterine systems as compared to copper intrauterine devices. Journal of Sexual Medicine 9(4): 1065-1073, 2012

Contraception with a novel 'frameless' intrauterine levonorgestrel-releasing drug delivery system: a pilot study. European Journal of Contraception and Reproductive Health Care 5(4): 234-240, 2000

Contraception with a novel frameless intrauterine levonorgestrel-releasing drug delivery system: a pilot study. European Journal of Contraception & Reproductive Health Care 5(4): 234-240, 2000

Comparison of copper intrauterine device with levonorgestrel-bearing intrauterine system for post-abortion contraception. Journal of Obstetrics and Gynaecology Research 41(9): 1426-1432, 2015

Comparison of two cohorts of women who expulsed either a copper-intrauterine device or a levonorgestrel-releasing intrauterine system. Journal of Obstetrics and Gynaecology Research 42(5): 554-559, 2016

Contraception and treatment in the perimenopause with a novel frameless intrauterine levonorgestrel-releasing drug delivery system: An extended pilot study. Contraception 66(2): 93-99, 2002