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Laparoscopic radical cystectomy with extended pelvic lymph node dissection for bladder urothelial carcinoma: complications and oncologic outcomes in 210 cases



Laparoscopic radical cystectomy with extended pelvic lymph node dissection for bladder urothelial carcinoma: complications and oncologic outcomes in 210 cases



Nan Fang Yi Ke Da Xue Xue Bao 32(7): 1012-1015



To investigate the complications and oncologic outcomes of 210 cases of bladder urothelial carcinoma (BUC) treated with laparoscopic radical cystectomy (LRC) with extended pelvic lymph node dissection (EPLND) and assess the feasibility and safety of this surgical technique. From January, 2003 to March 2010, 210 patients with BUC underwent LRC with EPLND. The cases with positive lymph nodes or T3a disease received adjuvant chemotherapy after the operation. The complications and oncologic results were recorded and analyzed. The mean operative time was 105 min in these cases with a mean blood loss of 220 ml and a rate of perioperative blood transfusion of 20.5%. The mean number of harvested lymph nodes was 17.6, and 42 (20%) cases were found to have positive lymph nodes. Minor and major perioperative complications occurred in 19% and 5.3% of the cases, respectively. The 5-year estimated overall survival, cancer-specific survival, recurrence-free survival and metastasis-free survival rates were 73.8%, 83.3%, 81.8% and 90.5%, respectively. LRC with EPLND is a safe and feasible technique for management of BUC and can produce satisfactory oncologic results.

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Accession: 054072656

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PMID: 22820589


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