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Less is more: structures of difficult targets with minimal constraints



Less is more: structures of difficult targets with minimal constraints



Structure 22(9): 1223-1224



By merging recent experimental and computational methodology advances, resolution-adapted structural recombination Rosetta has emerged as a powerful strategy for solving the structure of traditionally challenging targets. In this issue of Structure, Sgourakis and colleagues solve the structure of one such target, the immunoevasin protein m04, using this approach.

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Accession: 054106376

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PMID: 25185825

DOI: 10.1016/j.str.2014.08.004


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