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Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome



Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome



La Revue de Medecine Interne 30(3): 255-259



Among microangiopathic disorders of pregnancy, catastrophic antiphospholipid syndrome (CAPS) is a maternal and fetal life-threatening disorder. Hepatic involvement of this multi-systemic disorder can be confused with HELLP syndrome, occurring usually later in the course of pregnancy. We report a case of probable CAPS with hepatic disease in a pregnant woman at 13 week's gestation, with antiphospholipid syndrome and biological features of HELLP syndrome. Unspecific hepatic imaging, well-described in our case allowed undelayed therapy. CAPS and HELLP syndrome, both severe microangiopathic disorders, may be associated. Nosological distinction does not modify treatment strategy, which is a maternal and foetal emergency, but their overlapping requires aggressive and early management.

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Accession: 054146187

Download citation: RISBibTeXText

PMID: 19131145

DOI: 10.1016/j.revmed.2008.09.013


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