+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Long and short lipid molecules experience the same interleaflet drag in lipid bilayers



Long and short lipid molecules experience the same interleaflet drag in lipid bilayers



Physical Review Letters 110(26): 268101



Membrane interleaflet viscosity ηe affects tether formation, phase separation into domains, cell shape changes, and budding. Contrary to the expected contribution to interleaflet coupling from interdigitation, the slide of lipid patches in opposing monolayers conferred the same value ηe≈3×10(9)  J s m-4 for the friction experienced by the ends of both short and long chain fluorescent lipid analogues. Consistent with the weak dependence of the translational diffusion coefficient on lipid length, the in-layer viscosity was, albeit length dependent, much smaller than ηe.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 054158064

Download citation: RISBibTeXText

PMID: 23848924

DOI: 10.1103/PhysRevLett.110.268101


Related references

Interleaflet coupling and domain registry in phase-separated lipid bilayers. Biophysical Journal 100(4): 996-1004, 2011

Chloroform alters interleaflet coupling in lipid bilayers: an entropic mechanism. Journal of the Royal Society, Interface 12(106), 2016

Evidence for interleaflet slip during spreading of single lipid bilayers at hydrophilic solids. Chemphyschem 10(16): 2787-2790, 2010

On the effect of the solid support on the interleaflet distribution of lipids in supported lipid bilayers. Langmuir 21(1): 299-304, 2004

Interleaflet interaction and asymmetry in phase separated lipid bilayers: molecular dynamics simulations. Journal of the American Chemical Society 133(17): 6563-6577, 2011

Influence of the long-chain/short-chain amphiphile ratio on lateral diffusion of PEG-lipid in magnetically aligned lipid bilayers as measured via pulsed-field-gradient NMR. Biophysical Journal 89(3): 1850-1860, 2005

Probing Membrane Viscosity and Interleaflet Friction of Supported Lipid Bilayers by Tracking Electrostatically Adsorbed, Nano-Sized Vesicles. Small 12(46): 6338-6344, 2016

Interactions between lipid chains and non lipid molecules in bilayers a monte carlo study. Biophysical Journal 55(2 PART 2): 112A, 1989

Immobilizing single lipid and channel molecules in artificial lipid bilayers with annexin A5. Langmuir 22(14): 6302-6307, 2006

Investigating the order parameters of saturated lipid molecules under various curvature conditions on spherical supported lipid bilayers. Journal of Physical Chemistry. B 119(11): 4194-4202, 2015

Detection of unusual lipid mixing in cholesterol-rich phospholipid bilayers: the long and the short of it. Journal of the American Chemical Society 125(30): 8994-8995, 2004

Lipid transfer between small unilamellar vesicles and single bilayers on a solid support: Self-assembly of supported bilayers with asymmetric lipid distribution. Biochemistry 33(47): 14091-14099, 1994

The effect of cholesterol on short- and long-chain monounsaturated lipid bilayers as determined by molecular dynamics simulations and X-ray scattering. Biophysical Journal 95(6): 2792-2805, 2008

Triglyceride blisters in lipid bilayers: implications for lipid droplet biogenesis and the mobile lipid signal in cancer cell membranes. Plos One 5(9): E12811, 2011