+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Long-term outcomes of laparoscopic splenectomy versus open splenectomy for idiopathic thrombocytopenic purpura

Long-term outcomes of laparoscopic splenectomy versus open splenectomy for idiopathic thrombocytopenic purpura

International Surgery 99(3): 286-290

The long-term outcomes of laparoscopic splenectomy (LS) versus open splenectomy (OS) in patients with idiopathic thrombocytopenic purpura (ITP) are not known. A retrospective analysis of 73 patients who underwent splenectomy (32 LS and 41 OS) for refractory ITP between April 2003 and June 2012 was conducted. LS was associated with shorter hospital stay (P = 0.01), less blood loss and blood transfusion during surgery, quicker resumption of oral diet (P < 0.0001), and earlier drain removal (P < 0.01). Conversion to OS was required in 4 patients (12.5%). Operation time was significantly longer in LS (P < 0.0001). Deep venous thrombosis (DVT) was observed in 1 patient after LS and in 4 patients after OS (P = 0.52). One patient died from intraperitoneal bleeding after OS, another patient developed pulmonary embolism. Median follow-up of 36 months was performed in LS group (29 of 32, 91%) and of 46 months in OS group (35 of 41, 85%), 25 patients (86%) in LS group and 32 (91%) in OS group reached sustained complete response (P = 0.792). Kaplan-Meier analysis showed that there was no significant difference in the relapse-free survival rate between the groups (P = 0.777). In conclusion, the long-term outcome of laparoscopic splenectomy is not different from that of open splenectomy for patients with ITP.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 054169214

Download citation: RISBibTeXText

PMID: 24833154

DOI: 10.9738/intsurg-d-13-00175.1

Related references

Long-term results after splenectomy in adult idiopathic thrombocytopenic purpura: comparison between open and laparoscopic procedures. Journal of Laparoendoscopic and Advanced Surgical Techniques. Part a 23(3): 192-198, 2013

Laparoscopic splenectomy for treatment of patients with idiopathic thrombocytopenic purpura. Comparison with open splenectomy. Surgical Endoscopy 13(6): 563-566, 1999

Laparoscopic versus open splenectomy in the treatment of idiopathic thrombocytopenic purpura: an Indian experience. Journal of the Indian Medical Association 110(12): 889-893, 2013

Open versus laparoscopic splenectomy for idiopathic thrombocytopenic purpura: clinical and economic analysis. Surgery 134(1): 45-52, 2003

Laparoscopic splenectomy for idiopathic thrombocytopenic purpura: outcome and long-term results. World Journal of Surgery 26(1): 111-114, 2002

Laparoscopic and open splenectomy for idiopathic thrombocytopenic purpura. Nihon Rinsho. Japanese Journal of Clinical Medicine 61(4): 599-603, 2003

Predictive Factors of Idiopathic Thrombocytopenic Purpura and Long-term Survival in Chinese Adults Undergoing Laparoscopic Splenectomy. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 26(5): 397-400, 2016

Hematological long-term results of laparoscopic splenectomy for patients with idiopathic thrombocytopenic purpura: a case control study. Surgical Endoscopy 18(5): 766-770, 2004

Laparoscopic vs open splenectomy in the treatment of idiopathic thrombocytopenic purpura. Cirugia Espanola 81(4): 192-196, 2007

An 18-year review of open and laparoscopic splenectomy for idiopathic thrombocytopenic purpura. American Journal of Surgery 193(5): 580-3; Discussion 583-4, 2007

High dose intravenous IgG followed by splenectomy versus splenectomy alone in idiopathic thrombocytopenic purpura refractory to steroids. Nouvelle Revue Francaise D'hematologie 29(5): 285-287, 1987

Laparoscopic versus open splenectomy for immune thrombocytopenic purpura. Surgery (st Louis). 121(1): 18-22, 1997

Platelet count on preoperative day 1 predicts the long-term responses to laparoscopic splenectomy for Chinese patients with medically refractory idiopathic thrombocytopenic purpura. Bmc Surgery 18(1): 108, 2018

Splenectomy for idiopathic thrombocytopenic purpura A systematic literature review of individual patient data to access predictors of response, long-term outcomes, and complications. Annals of Internal Medicine 135(12): 1047-1051, 18 December, 2001

Long-term results of splenectomy in idiopathic thrombocytopenic purpura. British Journal of Haematology 87(SUPPL 1): 250, 1994