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Long-term survival in high-grade soft-tissue sarcoma - prognostic factors in synovial sarcoma



Long-term survival in high-grade soft-tissue sarcoma - prognostic factors in synovial sarcoma



International Journal of Oncology 7(1): 161-169



One hundred and thirteen consecutive patients with synovial sarcoma of the extremity or trunk were studied retrospectively. Seventy-six patients had surgery of their primary tumor at our institution (37 elsewhere). Mean follow-up for survivors was 124 (13-302) months. Thirteen developed local recurrence and 62 pulmonary metastases. Increasing surgical margin, adjuvant radiotherapy, and center-based treatment correlated with better local control. Older age, large tumor size and proximal position on the limb correlated with more metastases. Overall 5- and 10-year survival was 68 and 56%, respectively. Age, size, metastasis, metastasis free period and center-based treatment were independently prognostic.

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Accession: 054172703

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PMID: 21552822

DOI: 10.3892/ijo.7.1.161


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