+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Media coverage of off-label promotion: a content analysis of US newspapers



Media coverage of off-label promotion: a content analysis of US newspapers



Research in Social and Administrative Pharmacy 7(3): 257-271



Promotion of drugs for off-label use is newsworthy, because it is an illegal but all too common strategy used by pharmaceutical companies. The print media are an important source of information about coverage of off-label promotion of drugs and devices and can influence public perceptions of the practice. Print media coverage of off-label promotion during the years 1990-2008 were described and quantified. The primary themes and general tones relating to off-label promotion articles were evaluated. General concerns associated with off-label promotion and complaints about specific brand name drugs were also identified. Content analyses of the top 6 US newspapers were conducted over the period of 1990-2008 to analyze the media coverage given to off-label promotion of drugs and devices. Headlines and full text of articles were analyzed for primary themes and tones of the coverage. Intercoder reliability tests were performed on all the study variables. One hundred and one articles were identified meeting the study inclusion criteria. Coverage varied by newspaper. The Wall Street Journal had the most coverage on the topic (45%), and USA Today and Chicago Tribune had the least coverage (5%). Overall, most of the stories sampled were deemed to have a negative tone in coverage (77%), focusing mainly on lawsuits against drug companies for promoting their drugs for off-label uses. Pfizer's Neurontin(®) (Pfizer Inc., New York, NY 10017, USA) and Johnson & Johnson's Retin-A(®) (Orthoneutrogena, Los Angeles, CA 90045, USA) received the most media attention. The news media helps shape public understanding of promotional practices of pharmaceutical companies and their potential benefits and harms. This study suggests that print media coverage is generally negative about off-label promotion, focusing on legal actions taken against drug companies and the negative consequences of such promotional practices.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 054303191

Download citation: RISBibTeXText

PMID: 21272550

DOI: 10.1016/j.sapharm.2010.06.003


Related references

News media coverage of euthanasia: a content analysis of Dutch national newspapers. Bmc Medical Ethics 14: 11, 2013

Media Coverage of Climate Change in Chile: A Content Analysis of Conservative and Liberal Newspapers. Environmental Communication / A Journal of Nature and Culture 6(1): 64-81, 2012

Print media coverage of post-traumatic stress disorder: content analysis of three major Korean newspapers. Journal of Korean Medical Science 28(7): 1077-1082, 2014

How does media coverage effect the consumption of antidepressants? A study of the media coverage of antidepressants in Danish online newspapers 2010-2011. Research in Social and Administrative Pharmacy 14(7): 638-644, 2017

A content analysis of the coverage of physical activity in two Canadian newspapers. International Review for the Sociology of Sport 21(2-3): 141-151, 1986

A content analysis of smokeless tobacco coverage in U.S. newspapers and news wires. Nicotine and Tobacco Research 15(7): 1289-1296, 2014

Coverage of common cancer types in UK national newspapers: a content analysis. BMJ Open 4(7): E004677-E004677, 2014

A content analysis of news coverage of skin cancer in China newspapers. Health Communication 25(8): 647-649, 2011

Content analysis of news coverage on cancer prevention and screening in Japanese newspapers. Japanese Journal of Public Health 64(2): 85-94, 2017

A content analysis of news coverage of the HPV vaccine by U.S. newspapers, January 2002-June 2005. Journal of Women's Health 15(7): 803-809, 2006

Content analysis of coverage of alcohol control policy issues in black-oriented and mainstream newspapers in the U.S. Journal of Public Health Policy 18(1): 49-66, 1997

Promotion of waterpipe tobacco use, its variants and accessories in young adult newspapers: a content analysis of message portrayal. Health Education Research 30(1): 152-161, 2016

Electromagnetic hypersensitivity (EHS) in the media - a qualitative content analysis of Norwegian newspapers. Jrsm Short Reports 4(11): 2042533313487332, 2013

Representations of the health value of vitamin D supplementation in newspapers: media content analysis. BMJ Open 4(12): E006395, 2015

Media framing and construction of childhood obesity: a content analysis of Swedish newspapers. Obesity Science and Practice 4(1): 4-13, 2018