Section 55
Chapter 54,338

Meta-analysis of the association between adiponectin gene +276g/T polymorphisms and coronary atherosclerotic heart disease

Zhang, Z.; Tian, H.; Zhao, Y.; Ma, A.; Lu, Q.; Han, J.; Liu, Y.; Tian, H.

Wei Sheng Yan Jiu 42(4): 693-697


ISSN/ISBN: 1000-8020
PMID: 24024387
Accession: 054337524

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systemically evaluate the association between +276G/T single nucleotide polymorphisms of adiponectin gene and coronary atherosclerotic heart disease in Chinese population. 8 case-control studies about +276G/T polymorphism that were based on our inclusion criterion and available in the literature were reviewed. Meta analysis was carried out by Review Manager 4.2 software. Results from Metaanalysis demonstrated no significant heterogeneity among the studies about +276G/T polymorphisms and showed significant association between the +276G/T polymorphism and coronary disease in the Chinese population, and the fixed effects OR of the allele +276G to susceptibility of the disease was (OR = 1.93, 95% CI 1.32-2.82, P = 0.0007). The current paper on Meta-analysis demonstrated a correlation between the +276G/T single nucleotide polymorphism and the cononary disease in Chinese population.

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