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Metal-free nitro-carbocyclization of activated alkenes: a direct approach to synthesize oxindoles by cascade C-N and C-C bond formation

Metal-free nitro-carbocyclization of activated alkenes: a direct approach to synthesize oxindoles by cascade C-N and C-C bond formation

Chemical Communications 50(5): 554-556

A novel and direct metal-free nitro-carbocyclization of activated alkenes leading to valuable nitro-containing oxindoles via cascade C-N and C-C bond formation has been developed. The mechanistic study indicates that the initial NO and NO2 radical addition and the following C-H functionalization processes are involved in this transformation.

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Accession: 054346879

Download citation: RISBibTeXText

PMID: 24266027

DOI: 10.1039/c3cc47336h

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