Section 55

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Liu, Y.; Tang, G.; Li, Y.; Wang, Y.; Chen, X.; Gu, X.; Zhang, Z.; Wang, Y.; Yang, G.-Y. 2014: Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion. Journal of Neuroinflammation 11: 177
Xiao, H.; Ma, X.; Feng, W.; Fu, Y.; Lu, Z.; Xu, M.; Shen, Q.; Zhu, Y.; Zhang, Y. 2010: Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway. Cardiovascular Research 87(3): 504-513
Son, H.-J.; Lee, J.; Lee, S.-Y.; Kim, E.-K.; Park, M.-J.; Kim, K.-W.; Park, S.-H.; Cho, M.-L. 2014: Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis. Mediators of Inflammation 2014: 973986
Rattan, R.; Giri, S.; Hartmann, L.C.; Shridhar, V. 2011: Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner. Journal of Cellular and Molecular Medicine 15(1): 166-178
Simon-Szabó, L.; Kokas, M.ár.; Mandl, J.óz.; Kéri, G.ör.; Csala, M.ós. 2014: Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. Plos one 9(6): E97868
Alhaider, A.A.; Korashy, H.M.; Sayed-Ahmed, M.M.; Mobark, M.; Kfoury, H.; Mansour, M.A. 2011: Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression. Chemico-Biological Interactions 192(3): 233-242
Calixto, M.C.; Lintomen, L.íc.; André, D.M.; Leiria, L.O.ór.; Ferreira, D.; Lellis-Santos, C.; Anhê, G.F.; Bordin, S.; Landgraf, R.G.; Antunes, E. 2013: Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. Plos one 8(10): E76786
Algire, C.; Zakikhani, M.; Blouin, M.-J.; Shuai, J.H.; Pollak, M. 2008: Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth. Endocrine-Related Cancer 15(3): 833-839
Zhang, C.-X.; Pan, S.-N.; Meng, R.-S.; Peng, C.-Q.; Xiong, Z.-J.; Chen, B.-L.; Chen, G.-Q.; Yao, F.-J.; Chen, Y.-L.; Ma, Y.-D.; Dong, Y.-G. 2011: Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats. Clinical and Experimental Pharmacology and Physiology 38(1): 55-62
Carvajal, R.; Rosas, C.; Kohan, K.; Gabler, F.; Vantman, D.; Romero, C.; Vega, M. 2013: Metformin augments the levels of molecules that regulate the expression of the insulin-dependent glucose transporter GLUT4 in the endometria of hyperinsulinemic PCOS patients. Human Reproduction 28(8): 2235-2244
Kim, D.-L. 2013: Metformin based dual-combination therapies in drug naïve type 2 diabetic patients. Diabetes and Metabolism Journal 37(6): 429-432
Glueck, C.J.; Wang, P. 2007: Metformin before and during pregnancy and lactation in polycystic ovary syndrome. Expert Opinion on Drug Safety 6(2): 191-198
Cerezo, M.ël.; Tichet, M.él.; Abbe, P.; Ohanna, M.ël.; Lehraiki, A.; Rouaud, F.; Allegra, M.; Giacchero, D.; Bahadoran, P.; Bertolotto, C.; Tartare-Deckert, S.; Ballotti, R.; Rocchi, S.ép. 2013: Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner. Molecular Cancer Therapeutics 12(8): 1605-1615
Hwang, Y.P.; Jeong, H.G. 2010: Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Calpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activator protein-1. British Journal of Pharmacology 160(5): 1195-1211
Algire, C.; Amrein, L.; Zakikhani, M.; Panasci, L.; Pollak, M. 2010: Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase. Endocrine-Related Cancer 17(2): 351-360
O'Hora, T.R.; Markos, F.; Wiernsperger, N.F.; Noble, M.I.M. 2012: Metformin causes nitric oxide-mediated dilatation in a shorter time than insulin in the iliac artery of the anesthetized pig. Journal of Cardiovascular Pharmacology 59(2): 182-187
Obeid, R. 2014: Metformin causing vitamin B12 deficiency: a guilty verdict without sufficient evidence. Diabetes Care 37(2): E22-E23
Xie, Y.; Peng, Z.; Shi, M.; Ji, M.; Guo, H.; Shi, H. 2014: Metformin combined with p38 MAPK inhibitor improves cisplatin sensitivity in cisplatin‑resistant ovarian cancer. Molecular Medicine Reports 10(5): 2346-2350
Silva, J.C.; Pacheco, C.; Bizato, J.; de Souza, B.ár.V.; Ribeiro, T.ís.E.; Bertini, A.M. 2010: Metformin compared with glyburide for the management of gestational diabetes. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics 111(1): 37-40
Moore, L.E.; Clokey, D.; Rappaport, V.J.; Curet, L.B. 2010: Metformin compared with glyburide in gestational diabetes: a randomized controlled trial. Obstetrics and Gynecology 115(1): 55-59
Grisouard, J.; Timper, K.; Bouillet, E.; Radimerski, T.; Dembinski, K.; Frey, D.M.; Peterli, R.; Zulewski, H.; Keller, U.; Müller, B.; Christ-Crain, M. 2011: Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes. Archives of Physiology and Biochemistry 117(4): 209-214
Tosca, L.; Froment, P.; Rame, C.; McNeilly, J.R.; McNeilly, A.S.; Maillard, V.; Dupont, J. 2011: Metformin decreases GnRH- and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5' monophosphate-activated protein kinase (PRKA). Biology of Reproduction 84(2): 351-362
Tosca, L.; Ramé, C.; Chabrolle, C.; Tesseraud, S.; Dupont, J.ël. 2010: Metformin decreases IGF1-induced cell proliferation and protein synthesis through AMP-activated protein kinase in cultured bovine granulosa cells. Reproduction 139(2): 409-418
Zhao, D.; Long, X.-D.; Lu, T.-F.; Wang, T.; Zhang, W.-W.; Liu, Y.-X.; Cui, X.-L.; Dai, H.-J.; Xue, F.; Xia, Q. 2015: Metformin decreases IL-22 secretion to suppress tumor growth in an orthotopic mouse model of hepatocellular carcinoma. International Journal of Cancer 136(11): 2556-2565
Tan, B.K.; Adya, R.; Chen, J.; Farhatullah, S.; Heutling, D.; Mitchell, D.; Lehnert, H.; Randeva, H.S. 2009: Metformin decreases angiogenesis via NF-kappaB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1. Cardiovascular Research 83(3): 566-574
Oktenli, C.; Ozgurtas, T.; Dede, M.; Sanisoglu, Y.S.; Yenen, M.C.; Yesilova, Z.; Kenar, L.; Kurt, Y.G.; Baser, I.; Smith, J.; Cianflone, K. 2007: Metformin decreases circulating acylation-stimulating protein levels in polycystic ovary syndrome. Gynecological Endocrinology: the Official Journal of the International Society of Gynecological Endocrinology 23(12): 710-715
Campagnoli, C.; Berrino, F.; Venturelli, E.; Abbà, C.; Biglia, N.; Brucato, T.; Cogliati, P.; Danese, S.; Donadio, M.; Zito, G.; Pasanisi, P. 2013: Metformin decreases circulating androgen and estrogen levels in nondiabetic women with breast cancer. Clinical Breast Cancer 13(6): 433-438
Fendt, S.-M.; Bell, E.L.; Keibler, M.A.; Davidson, S.M.; Wirth, G.J.; Fiske, B.; Mayers, J.R.; Schwab, M.; Bellinger, G.; Csibi, A.; Patnaik, A.; Blouin, M.J.; Cantley, L.C.; Guarente, L.; Blenis, J.; Pollak, M.N.; Olumi, A.F.; Vander Heiden, M.G.; Stephanopoulos, G. 2013: Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism. Cancer Research 73(14): 4429-4438
Sumitani, S.; Morita, S.; Deguchi, R.; Hirai, K.; Mukai, K.; Utsu, Y.; Miki, S.; Sato, B.; Nakamura, H.; Kasayama, S.; Koga, M. 2015: Metformin decreases glycated albumin to glycated haemoglobin ratio in patients with newly diagnosed type 2 diabetes. Annals of Clinical Biochemistry 52(Part 1): 76-81
Kim, D.; Lee, J.E.; Jung, Y.J.; Lee, A.S.; Lee, S.; Park, S.K.; Kim, S.H.; Park, B.-H.; Kim, W.; Kang, K.P. 2013: Metformin decreases high-fat diet-induced renal injury by regulating the expression of adipokines and the renal AMP-activated protein kinase/acetyl-CoA carboxylase pathway in mice. International Journal of Molecular Medicine 32(6): 1293-1302
Tsai, M.-J.; Yang, C.-J.; Kung, Y.-T.; Sheu, C.-C.; Shen, Y.-T.; Chang, P.-Y.; Huang, M.-S.; Chiu, H.-C. 2014: Metformin decreases lung cancer risk in diabetic patients in a dose-dependent manner. Lung Cancer 86(2): 137-143
Gómez-Díaz, R.A.; Talavera, J.O.; Pool, E.Canché.; Ortiz-Navarrete, F.Vianney.; Solórzano-Santos, F.; Mondragón-González, R.; Valladares-Salgado, A.; Cruz, M.; Aguilar-Salinas, C.A.; Wacher, N.H. 2012: Metformin decreases plasma resistin concentrations in pediatric patients with impaired glucose tolerance: a placebo-controlled randomized clinical trial. Metabolism, Clinical and Experimental 61(9): 1247-1255
Elia, E.M.; Quintana, R.; Carrere, C.; Bazzano, M.ía.V.; Rey-Valzacchi, G.ón.; Paz, D.A.; Pustovrh, M.ía.C. 2013: Metformin decreases the incidence of ovarian hyperstimulation syndrome: an experimental study. Journal of Ovarian Research 6(1): 62
Morteza Taghavi, S.; Rokni, H.; Fatemi, S. 2011: Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrome and hypothyroidism. Diabetes and Vascular Disease Research 8(1): 47-48
Quentin, T.; Steinmetz, M.; Poppe, A.; Thoms, S. 2012: Metformin differentially activates ER stress signaling pathways without inducing apoptosis. Disease Models and Mechanisms 5(2): 259-269
Andrzejewski, S.; Gravel, S.-P.; Pollak, M.; St-Pierre, J. 2014: Metformin directly acts on mitochondria to alter cellular bioenergetics. Cancer and Metabolism 2: 12
Mansour, A.A.; Habib, O.S. 2007: Metformin discontinuation rate among patients with type-2 diabetes mellitus in Basrah, Iraq. Saudi Medical Journal 28(12): 1919-1921
Anonymous 2008: Metformin dispersible tablets: line extension. A welcome formulation of an essential drug. Prescrire international 17(96): 138
Zi, F.-M.; He, J.-S.; Li, Y.; Wu, C.; Yang, L.; Yang, Y.; Wang, L.-J.; He, D.-H.; Zhao, Y.; Wu, W.-J.; Zheng, G.-F.; Han, X.-Y.; Huang, H.; Yi, Q.; Cai, Z. 2015: Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models. Cancer Letters 356(2 Part B): 443-453
Kisfalvi, K.; Eibl, G.; Sinnett-Smith, J.; Rozengurt, E. 2009: Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Research 69(16): 6539-6545
Tsilidis, K.K.; Capothanassi, D.; Allen, N.E.; Rizos, E.C.; Lopez, D.S.; van Veldhoven, K.; Sacerdote, C.; Ashby, D.; Vineis, P.; Tzoulaki, I.; Ioannidis, J.P.A. 2014: Metformin does not affect cancer risk: a cohort study in the U.K. Clinical Practice Research Datalink analyzed like an intention-to-treat trial. Diabetes Care 37(9): 2522-2532
Ortega, J.F.; Hamouti, N.; Fernández-Elías, Vín.E.; de Prada, Mía.V.Guío.; Martínez-Vizcaíno, V.; Mora-Rodríguez, R. 2014: Metformin does not attenuate the acute insulin-sensitizing effect of a single bout of exercise in individuals with insulin resistance. Acta Diabetologica 51(5): 749-755
Anonymous 2007: Metformin does not harm diabetic patients with heart failure. Journal of Family Practice 56(12): 996
Bhat, M.; Chaiteerakij, R.; Harmsen, W.S.; Schleck, C.D.; Yang, J.D.; Giama, N.H.; Therneau, T.M.; Gores, G.J.; Roberts, L.R. 2014: Metformin does not improve survival in patients with hepatocellular carcinoma. World Journal of Gastroenterology 20(42): 15750-15755
Aubuchon, M.; Lieman, H.; Stein, D.; Cohen, H.W.; Isaac, B.; Adel, G.; Weitzman, V.; Tetrokalashvili, M.; Polotsky, A.J.; Santoro, N. 2009: Metformin does not improve the reproductive or metabolic profile in women with polycystic ovary syndrome (PCOS). Reproductive Sciences 16(10): 938-946
Chak, A.; Buttar, N.S.; Foster, N.R.; Seisler, D.K.; Marcon, N.E.; Schoen, R.; Cruz-Correa, M.R.; Falk, G.W.; Sharma, P.; Hur, C.; Katzka, D.A.; Rodriguez, L.M.; Richmond, E.; Sharma, A.N.; Smyrk, T.C.; Mandrekar, S.J.; Limburg, P.J. 2015: Metformin does not reduce markers of cell proliferation in esophageal tissues of patients with Barrett's esophagus. Clinical Gastroenterology and Hepatology: the Official Clinical Practice Journal of the American Gastroenterological Association 13(4): 665-72.E1-4
Bershteĭn, L.M.; Turkevich, E.A.; Boiarkina, M.P. 2012: Metformin does not suppress the aromatase expression in breast cancer tissue of patients with concurrent type 2 diabetes. Voprosy Onkologii 58(2): 194-198
Davidson, M.B.; Ramos, L. 2008: Metformin does not suppress thyrotropin. Endocrine Practice: Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 14(2): 252-253
Sarfstein, R.; Friedman, Y.; Attias-Geva, Z.; Fishman, A.; Bruchim, I.; Werner, H. 2013: Metformin downregulates the insulin/IGF-i signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners. Plos one 8(4): E61537
Legro, R.S. 2010: Metformin during pregnancy in polycystic ovary syndrome: another vitamin bites the dust. Journal of Clinical Endocrinology and Metabolism 95(12): 5199-5202
Popovich, I.G.; Piskunova, T.S.; Tyndyk, M.L.; Anikin, I.V.; Zabezhinskiĭ, M.A.; Anisimov, V.N. 2012: Metformin effect on urethane-induced tumorigenesis in mice. Voprosy Onkologii 58(4): 549-553
Ben Ayed, B.; Dammak dit Mlik, S.; Ben Arab, H.; Trabelssi, H.; Chahtour, H.; Mathlouthi, N.; Dhuib, M.; Kassis, M.; Saiidane, D.; Trabelssi, K.; Guermazi, M. 2009: Metformin effects on clomifene-induced ovulation in the polycystic ovary syndrome. La Tunisie Medicale 87(1): 43-49
Damjanović, A.; Matić, I.Z.; Ðorđić, M.; Ðurović, M.N.ć; Nikolić, S.đa.; Roki, K.; Milovanović, Z.; Antić-Stanković, J.; Džodić, R.; Damjanović, S.; Kanjer, K.; Abu Rabi, Z.; Juranić, Z. 2015: Metformin effects on malignant cells and healthy PBMC; the influence of metformin on the phenotype of breast cancer cells. Pathology Oncology Research: Por 21(3): 605-612
Romualdi, D.; Giuliani, M.; Cristello, F.; Fulghesu, A.M.; Selvaggi, L.; Lanzone, A.; Guido, M. 2010: Metformin effects on ovarian ultrasound appearance and steroidogenic function in normal-weight normoinsulinemic women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial. Fertility and Sterility 93(7): 2303-2310
Andújar-Plata, P.; Pi-Sunyer, X.; Laferrère, B. 2012: Metformin effects revisited. Diabetes Research and Clinical Practice 95(1): 1-9
Ferreira, C.B.N.D.; Cesaretti, Mário.Luís.R.; Ginoza, M.; Kohlmann, O. 2009: Metformin effects upon blood pressure and glucose metabolism of monossodium glutamate induced-obese spontaneously hypertensive rats. Arquivos Brasileiros de Endocrinologia e Metabologia 53(4): 409-415
Kedikova, S.; Sirakov, M.; Boyadzhieva, M. 2012: Metformin efficiency for the adolescent PCOS treatment. Akusherstvo i Ginekologiia 51(6): 6-10
Lin, C.-C.; Yeh, H.-H.; Huang, W.-L.; Yan, J.-J.; Lai, W.-W.; Su, W.-P.; Chen, H.H.W.; Su, W.-C. 2013: Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway. American Journal of Respiratory Cell and Molecular Biology 49(2): 241-250
Kim, M.-H.; Jee, J.-H.; Park, S.; Lee, M.-S.; Kim, K.-W.; Lee, M.-K. 2014: Metformin enhances glucagon-like peptide 1 via cooperation between insulin and Wnt signaling. Journal of Endocrinology 220(2): 117-128
Liu, Y.; Huang, C.; Ceng, C.; Zhan, H.; Zheng, D.; Han, W. 2014: Metformin enhances nitric oxide production and diminishes Rho kinase activity in rats with hyperlipidemia. Lipids in Health and Disease 13: 115
Ma, J.; Guo, Y.; Chen, S.; Zhong, C.; Xue, Y.; Zhang, Y.; Lai, X.; Wei, Y.; Yu, S.; Zhang, J.; Liu, W. 2014: Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma. Bmc Cancer 14: 172
Kanazawa, I.; Yamaguchi, T.; Yano, S.; Yamauchi, M.; Sugimoto, T. 2008: Metformin enhances the differentiation and mineralization of osteoblastic MC3T3-E1 cells via AMP kinase activation as well as eNOS and BMP-2 expression. Biochemical and Biophysical Research Communications 375(3): 414-419
Pyla, R.; Osman, I.; Pichavaram, P.; Hansen, P.; Segar, L. 2014: Metformin exaggerates phenylephrine-induced AMPK phosphorylation independent of CaMKKβ and attenuates contractile response in endothelium-denuded rat aorta. Biochemical Pharmacology 92(2): 266-279
Miller, R.C.; Murley, J.S.; Grdina, D.J. 2014: Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs. Radiation Research 181(5): 464-470
Tartarin, P.; Moison, D.; Guibert, E.; Dupont, J.; Habert, R.; Rouiller-Fabre, V.; Frydman, N.; Pozzi, S.; Frydman, R.; Lecureuil, C.; Froment, P. 2012: Metformin exposure affects human and mouse fetal testicular cells. Human Reproduction 27(11): 3304-3314
Spillane, S.; Bennett, K.; Sharp, L.; Barron, T.I. 2014: Metformin exposure and disseminated disease in patients with colorectal cancer. Cancer Epidemiology 38(1): 79-84
Niemuth, N.J.; Jordan, R.; Crago, J.; Blanksma, C.; Johnson, R.; Klaper, R.D. 2015: Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish. Environmental Toxicology and Chemistry 34(2): 291-296
Wilson, D.M.; Abrams, S.H.; Aye, T.; Lee, P.D.K.; Lenders, C.; Lustig, R.H.; Osganian, S.V.; Feldman, H.A.; Wilson, D.M.; Fechner, P.; Aye, T.; Robinson, T.; Buckingham, B.; Esrey, T.; McNeil, K.; Sorensen, B.; Wilson, K.; Davis, J.; Klish, W.; Abrams, S.; Holt, P.; Edwards, C.; Howard, L.; Gitelman, S.; Lustig, R.; Wertz, M.; Breland, J.; Lihatsh, T.; Lee, P.D.K.; Haddal, A.; Cohen, P.; Shupien, S.; Mooney, J.; Khanukhova, E.; Cohen, H.; Lenders, C.; Taylor, G.; Duggan, C.; Nurko, S.; Sweeney, C.; Zhang, K. 2010: Metformin extended release treatment of adolescent obesity: a 48-week randomized, double-blind, placebo-controlled trial with 48-week follow-up. Archives of Pediatrics and Adolescent Medicine 164(2): 116-123
Anisimov, V.N.; Egormin, P.A.; Piskunova, T.S.; Popovich, I.G.; Tyndyk, M.L.; Yurova, M.N.; Zabezhinski, M.A.; Anikin, I.V.; Karkach, A.S.; Romanyukha, A.A. 2010: Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle 9(1): 188-197
Anisimov, V.N. 2010: Metformin for aging and cancer prevention. Aging 2(11): 760-774
Correll, C.U.; Sikich, L.; Reeves, G.; Riddle, M. 2013: Metformin for antipsychotic-related weight gain and metabolic abnormalities: when, for whom, and for how long?. American Journal of Psychiatry 170(9): 947-952
Hasnain, M.; Vieweg, W.Victor.R.; Fredrickson, S.K. 2010: Metformin for atypical antipsychotic-induced weight gain and glucose metabolism dysregulation: review of the literature and clinical suggestions. Cns Drugs 24(3): 193-206
Yang, Y. 2011: Metformin for cancer prevention. Frontiers of Medicine 5(2): 115-117
Lexis, C.P.H.; van der Horst, I.C.C. 2014: Metformin for cardiovascular disease: promise still unproven. LANCET. Diabetes and Endocrinology 2(2): 94-95
Hamilton, R.J. 2014: Metformin for castrate-resistant prostate cancer: learning more about an old dog's new tricks. European Urology 66(3): 475-477; Discussion: 477-478
Preiss, D.; Lloyd, S.M.; Ford, I.; McMurray, J.J.; Holman, R.R.; Welsh, P.; Fisher, M.; Packard, C.J.; Sattar, N. 2014: Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial. LANCET. Diabetes and Endocrinology 2(2): 116-124
Park, M.H.; Kinra, S.; Ward, K.J.; White, B.; Viner, R.M. 2009: Metformin for obesity in children and adolescents: a systematic review. Diabetes Care 32(9): 1743-1745
Praharaj, S.K.; Jana, A.K.; Goyal, N.; Sinha, V.K. 2011: Metformin for olanzapine-induced weight gain: a systematic review and meta-analysis. British Journal of Clinical Pharmacology 71(3): 377-382
Worsley, R.; Jane, F.; Robinson, P.J.; Bell, R.J.; Davis, S.R. 2015: Metformin for overweight women at midlife: a double-blind, randomized, controlled trial. Climacteric: the Journal of the International Menopause Society 18(2): 270-277
Milewicz, A. 2013: Metformin for polycystic ovary syndrome. Endokrynologia Polska 64(5): 409-414
Sehdev, A.; Shih, Y-Chen.T.; Vekhter, B.; Bissonnette, M.B.; Olopade, O.I.; Polite, B.N. 2015: Metformin for primary colorectal cancer prevention in patients with diabetes: a case-control study in a US population. Cancer 121(7): 1071-1078
Tanaka, Y.; Kita, K.; Takao, R.; Amano, H.; Uchida, R.; Shiozaki, Y.; Yonetani, Y.; Kinugasa, K.; Mae, T.; Horibe, S. 2018: Chronicity of Anterior Cruciate Ligament Deficiency, Part 2: Radiographic Predictors of Early Graft Failure. Orthopaedic Journal of Sports Medicine 6(2): 2325967117751915
Cohen, P. 2009: Metformin for the prevention of androgen deprivation induced metabolic syndrome, obesity and type 2 diabetes. Medical Hypotheses 72(2): 227-228
Codner, E.; Iñíguez, G.án.; López, P.; Mujica, V.ón.; Eyzaguirre, F.C.; Asenjo, S.; Torrealba, I.; Cassorla, F. 2013: Metformin for the treatment of hyperandrogenism in adolescents with type 1 diabetes mellitus. Hormone Research in Paediatrics 80(5): 343-349
Nestler, J.E. 2008: Metformin for the treatment of the polycystic ovary syndrome. New England Journal of Medicine 358(1): 47-54
Wu, R.-R.; Jin, H.; Gao, K.; Twamley, E.W.; Ou, J.-J.; Shao, P.; Wang, J.; Guo, X.-F.; Davis, J.M.; Chan, P.K.; Zhao, J.-P. 2012: Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study. American Journal of Psychiatry 169(8): 813-821
Wang, M.; Tong, J.-h.; Zhu, G.; Liang, G.-m.; Yan, H.-f.; Wang, X.-z. 2012: Metformin for treatment of antipsychotic-induced weight gain: a randomized, placebo-controlled study. Schizophrenia Research 138(1): 54-57
Shin, L.; Bregman, H.; Breeze, J.L.; Noyes, N.; Frazier, J.A. 2009: Metformin for weight control in pediatric patients on atypical antipsychotic medication. Journal of Child and Adolescent Psychopharmacology 19(3): 275-279
Jarskog, L.F.; Hamer, R.M.; Catellier, D.J.; Stewart, D.D.; Lavange, L.; Ray, N.; Golden, L.H.; Lieberman, J.A.; Stroup, T.S.; Adler, L.; Burnie, G.; Barber, M.; Byerly, M.; Canive, J.M.; Glick, I.; Henderson, D.C.; Fredrik Jarskog, L.; Lamberti, J. S.; Khan, A.; McEvoy, J.P.; Meltzer, H.; Miller, A.; Miller, D.D.; Nasrallah, H.A.; Olson, S.; Patel, J.K.; Saltz, B.L. 2013: Metformin for weight loss and metabolic control in overweight outpatients with schizophrenia and schizoaffective disorder. American Journal of Psychiatry 170(9): 1032-1040
Tek, C.; Chwastiak, L. 2014: Metformin for weight loss in schizophrenia: safe but not a panacea. Evidence-Based Mental Health 17(2): 51-52
Björkhem-Bergman, L.; Asplund, A.B.; Lindh, J.D. 2011: Metformin for weight reduction in non-diabetic patients on antipsychotic drugs: a systematic review and meta-analysis. Journal of Psychopharmacology 25(3): 299-305
Łabuzek, K.; Liber, S.; Gabryel, B.że.; Okopień, B.ła. 2010: Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures. Pharmacological Reports: Pr 62(5): 827-848
Fougner, K.J.; Vanky, E.; Carlsen, S.M. 2008: Metformin has no major effects on glucose homeostasis in pregnant women with PCOS: results of a randomized double-blind study. Scandinavian Journal of Clinical and Laboratory Investigation 68(8): 771-776
Brown, S. 2014: Metformin has wider implications than diabetes. Post Reproductive Health 20(3): 89
Wiwanitkit, V. 2011: Metformin high dosage and bleeding episode: a clinical case study. Indian Journal of Endocrinology and Metabolism 15(2): 132-133
Cai, X.; Shao, W.; Luan, Y.; Pang, J.; Li, F.; Li, Z. 2011: Metformin hydrochloride-loaded poly(vinyl alcohol) composites as drug delivery systems. Journal of Nanoscience and Nanotechnology 11(10): 8621-8627
Kumar, A.; Al-Sammarraie, N.; DiPette, D.J.; Singh, U.S. 2014: Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. Oncotarget 5(22): 11709-11722
Takahashi, A.; Kimura, F.; Yamanaka, A.; Takebayashi, A.; Kita, N.; Takahashi, K.; Murakami, T. 2014: Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis. Cancer Cell International 14: 53
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Agarwal, N.; Rice, S.P.L.; Bolusani, H.; Luzio, S.D.; Dunseath, G.; Ludgate, M.; Rees, D.A. 2010: Metformin reduces arterial stiffness and improves endothelial function in young women with polycystic ovary syndrome: a randomized, placebo-controlled, crossover trial. Journal of Clinical Endocrinology and Metabolism 95(2): 722-730
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Algire, C.; Moiseeva, O.; Deschênes-Simard, X.; Amrein, L.; Petruccelli, L.; Birman, E.; Viollet, B.; Ferbeyre, G.; Pollak, M.N. 2012: Metformin reduces endogenous reactive oxygen species and associated DNA damage. Cancer Prevention Research 5(4): 536-543
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Dafopoulos, K.; Vrekoussis, T.; Chalvatzas, N.; Messini, C.I.; Kalantaridou, S.N.; Georgoulias, P.; Messinis, I.E.; Makrigiannakis, A. 2013: Metformin reduces the expression of corticotropin-releasing hormone and urocortin in the endometrium of healthy women. Fertility and Sterility 100(5): 1405-1409
Fonseca, E.A.I.; de Oliveira, M.A.; Lobato, N.úb.d.S.; Akamine, E.H.; Colquhoun, A.; de Carvalho, M.H.C.; Zyngier, S.B.; Fortes, Z.B. 2011: Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis. Life Sciences 88(19-20): 846-852
Tseng, C.-H. 2014: Metformin reduces thyroid cancer risk in Taiwanese patients with type 2 diabetes. Plos one 9(10): E109852
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Kim, D.-S.; Jeong, S.-K.; Kim, H.-R.; Kim, D.-S.; Chae, S.-W.; Chae, H.-J. 2010: Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells. Immunopharmacology and Immunotoxicology 32(2): 251-257
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Gritti, M.; Würth, R.; Angelini, M.; Barbieri, F.; Peretti, M.; Pizzi, E.; Pattarozzi, A.; Carra, E.; Sirito, R.; Daga, A.; Curmi, P.M.G.; Mazzanti, M.; Florio, T. 2014: Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current. Oncotarget 5(22): 11252-11268
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Shao, X.; Cao, X.; Song, G.; Zhao, Y.; Shi, B. 2014: Metformin rescues the MG63 osteoblasts against the effect of high glucose on proliferation. Journal of Diabetes Research 2014: 453940
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Neschen, S.; Scheerer, M.; Seelig, A.; Huypens, P.; Schultheiss, J.ür.; Wu, M.; Wurst, W.; Rathkolb, B.; Suhre, K.; Wolf, E.; Beckers, J.; Hrabé de Angelis, M. 2015: Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice. Diabetes 64(1): 284-290
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