+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Mid-, and long-term effects of video-assisted thoracoscopic and transsternal thymectomy in treatment of non-thymomatous myasthenia gravis: analysis of 204 cases



Mid-, and long-term effects of video-assisted thoracoscopic and transsternal thymectomy in treatment of non-thymomatous myasthenia gravis: analysis of 204 cases



Zhonghua Yi Xue Za Zhi 87(45): 3171-3173



To evaluate the mid-, and long-term effects of video-assisted thoracoscopic thymectomy and transsternal thymectomy in treatment of myasthenia gravis (MG) and to identify the prognostic factors for thymectomy success. 161 patients with non-thymomatous MS, 84 males and 120 females, aged 33, underwent transsternal thymectomy and were followed up for 5 years; and 43 patients with non-thymomatous MS A retrospective, 1 male and 25 females, 21 being aged >40 during operation, underwent thoracoscopic thymectomy and were followed up for 3 years. The mean operating time of the thoracoscopic group was (132 +/- 32) min minutes, significantly longer than that of the transsternal thymectomy group [(96 +/- 18) min, P = 0.000]. Four patients in the transsternal thymectomy group and 41 in the transsternal thymectomy group developed myasthenic crises (P = 0.023). The complete stable remission (CSR) rates 1, 2, and 3 years after operation of the thoracoscopic thymectomy group were 34.9%, 41.9%, and 46.5% respectively; and CSR rates 1, 2, 3, and 5 years after operation of the transsternal thymectomy group were 26.7%, 31.7%, 35.4%, and 40.4% respectively, without significant differences between these 2 groups. Both thoracoscopic and transsternal approaches to thymectomy in patients with MG are effective in terms of remission. The authors advocate adopting the thoracoscopic approach early.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 054383203

Download citation: RISBibTeXText

PMID: 18399107


Related references

Video-assisted thoracoscopic extended thymectomy and extended transsternal thymectomy in non-thymomatous myasthenia gravis patients. Journal of the Neurological Sciences 217(2): 233-4; Author Reply 235-6, 2004

Video-assisted thoracoscopic extended thymectomy and extended transsternal thymectomy (T-3b) in non-thymomatous myasthenia gravis patients: Remission after 6 years of follow-up. Journal of the Neurological Sciences 212(1-2): 31-36, 2003

Unilateral video-assisted thoracoscopic extended thymectomy offers long-term outcomes equivalent to that of the bilateral approach in the treatment of non-thymomatous myasthenia gravis. Interactive Cardiovascular and Thoracic Surgery 21(5): 610-615, 2015

Long-term effects of video-assisted thoracoscopic thymectomy for myasthenia gravis: 5-year follow-up of 18 cases. Zhonghua Yi Xue Za Zhi 86(33): 2312-2314, 2006

Video-assisted thoracoscopic surgery or transsternal thymectomy in the treatment of myasthenia gravis?. Interactive Cardiovascular and Thoracic Surgery 12(1): 40-46, 2011

The comparative analysis of video-assisted thoracoscopic versus transsternal thymectomy for myasthenia gravis. Zhonghua Wai Ke Za Zhi 47(5): 366-368, 2009

Thymectomy for Nonthymomatous Myasthenia Gravis: Comparison of Video-Assisted Thoracoscopic and Transsternal Thymectomy. Innovations 13(2): 77-80, 2018

Bilateral video-assisted thoracoscopic thymectomy vs. extended transsternal thymectomy in myasthenia gravis: a prospective study. European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes 37(4): 199-203, 2005

Video-assisted thoracoscopic extended thymectomy and transsternal extended thymectomy for treatment of myasthenia gravis: a case-control study. Nan Fang Yi Ke Da Xue Xue Bao 29(4): 794-797, 2009

Comparison between video-assisted thoracoscopic thymectomy and transternal thymectomy for myasthenia gravis (analysis of 82 cases). International Surgery 90(1): 36-41, 2005

Video-assisted thoracoscopic extended thymectomy in myasthenia gravis Two-year follow-up in 101 patients and comparison with the transsternal approach. Richman, D P Annals of the New York Academy of Sciences; Myasthenia gravis and related diseases: Disorders of the neuromuscular junction 749-752, 1998

Bilateral video-assisted thoracoscopic thymectomy has a surgical extent similar to that of transsternal extended thymectomy with more favorable early surgical outcomes for myasthenia gravis patients. Surgical Endoscopy 25(3): 849-854, 2011

Video-assisted thoracoscopic extended thymectomy (VATET) in myasthenia gravis. Two-year follow-up in 101 patients and comparison with the transsternal approach. Annals of the new York Academy of Sciences 841: 749-752, 1998

Video-assisted thoracoscopic thymectomy for non-thymomatous myasthenia gravis: a right-sided or left-sided approach?. Interactive Cardiovascular and Thoracic Surgery 25(4): 651-653, 2017

Video-assisted thoracoscopic extended thymectomy for myasthenia gravis: analysis of 107 cases. Zhonghua Wai Ke Za Zhi 43(10): 625-627, 2005