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Molecular characterization of Candida spp. isolates from patients with bloodstream infections

Molecular characterization of Candida spp. isolates from patients with bloodstream infections

Revista da Sociedade Brasileira de Medicina Tropical 46(6): 786-787

ISSN/ISBN: 0037-8682

PMID: 24142366

DOI: 10.1590/0037-8682-1718-2013

The aim of this study was to conduct an epidemiological study comparing the genetic similarity of yeasts isolated from blood cultures. Random amplification of polymorphic DNA (RAPD) techniques were used for the Candida samples obtained from patients at the Hospital Universitário da Universidade Federal do Mato Grosso do Sul (HU/UFMS) in Campo Grande, State of Mato Grosso do Sul, Brazil, from 1998-2000. The most frequently isolated species was Candida albicans (45.8%). DNA amplification from genomic yeast isolates indicated a genetic similarity of over 90%. The RAPD profiles obtained were able to differentiate between the isolated Candida species, thereby suggesting that the method might be useful in epidemiological studies.

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Accession: 054435386

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