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Neoadjuvant gemcitabine and cisplatin chemotherapy for locally advanced urothelial cancer of the bladder



Neoadjuvant gemcitabine and cisplatin chemotherapy for locally advanced urothelial cancer of the bladder



Cancer 118(1): 72-81



The purpose of this study was to investigate the effect of neoadjuvant chemotherapy with gemcitabine and cisplatin (GC) on pathologic down-staging of patients with locally advanced urothelial cancer (UC) of the bladder. This was a retrospective cohort study of patients treated with radical cystectomy (RC) for clinical stage cT2-T4, N any, M0 bladder UC at Strong Memorial Hospital from 1999 to 2009. The primary exposure variable was use of neoadjuvant chemotherapy (GC vs none). The primary outcome was stage pT0 at RC. Secondary outcomes included other down-staging end points in the bladder (

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Accession: 054567104

Download citation: RISBibTeXText

PMID: 21720989

DOI: 10.1002/cncr.26238


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