+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Neurodevelopmental outcome of preterm very low birth weight infants born from 2005 to 2007



Neurodevelopmental outcome of preterm very low birth weight infants born from 2005 to 2007



European Journal of Paediatric Neurology 16(6): 716-723



To evaluate short-term neurodevelopmental outcome (at 24 months of corrected age) and correlations with obstetric and neonatal factors in a sample of preterm very low birth weight infants born and admitted to an Italian tertiary centre between 2005 and 2007. 156 infants with a birth weight ≤ 1500 g (gestational age, range: 27-31 weeks) were followed at regular intervals through neurodevelopmental (neurological and psychomotor) assessment up to 24 months of corrected age. A statistical analysis was conducted in order to look for correlations between pre- and perinatal variables and neuropsychomotor outcome at 24 months. 131 children were classified as normal and the other 25 presented sequelae classified as "minor" in 17 cases and as "major" in eight. The most significant risk factors for a poor outcome were preterm premature rupture of the membranes, bronchodysplasia, late-onset sepsis, postnatal steroid therapy and male gender. The presence of severe abnormalities on brain ultrasound scan and of an abnormal neurological assessment at 40 weeks at term equivalent age were strong predictors of poor outcome. Our study is one of the few investigating the short-term outcome of preterm VLBW Italian children born in the second half of the 2000s. Neurodevelopmental assessment at 24 months revealed a marked reduction in major sequelae. Several risk factors for a poor neurodevelopmental outcome identified in children born in earlier periods were confirmed in these children born in recent years.

(PDF emailed within 0-6 h: $19.90)

Accession: 054580393

Download citation: RISBibTeXText

PMID: 22709626

DOI: 10.1016/j.ejpn.2012.05.006


Related references

Neurodevelopmental outcome of preterm very low birth weight infants born from 25 to 27. 2012

Long-Term Neurodevelopmental and Functional Outcomes of Infants Born Very Preterm and/or with a Very Low Birth Weight. Neonatology 115(4): 310-319, 2019

Neurodevelopmental outcome of very low birth weight infants born at the Perinatal Centre in Ulm, Germany. Zeitschrift für Geburtshilfe und Neonatologie 217(2): 65-71, 2013

Neurodevelopmental outcome of extremely low birth weight infants born in Finland in 1996-1997. Pediatric Research 49(4 Part 2): 332A, 2001

Long-term development of low-risk low birth weight preterm born infants: neurodevelopmental aspects from childhood to late adolescence. Early Human Development 85(7): 409-413, 2009

Neurodevelopmental outcome in relation to pre-discharge apnea in former preterm infants with birth weight less than 1250 G. Pediatric Research 39(4 PART 2): 260A, 1996

Perinatal infections and neurodevelopmental outcome in very preterm and very low-birth-weight infants: a meta-analysis. JAMA Pediatrics 167(7): 662-668, 2013

Head circumference catch-up growth among preterm very low birth weight infants: effect on neurodevelopmental outcome. Journal of Perinatal Medicine 39(5): 579-586, 2012

Neurodevelopmental outcome at 5 years of age of a national cohort of extremely low birth weight infants who were born in 1996-1997. Pediatrics 116(6): 1391-1400, 2005

The relation between neonatal thyroxine levels and neurodevelopmental outcome at age 5 and 9 years in a national cohort of very preterm and/or very low birth weight infants. Pediatric Research 39(1): 142-145, 1996

Periventricular echodensities detected by cranial ultrasonography: usefulness in predicting neurodevelopmental outcome in low-birth-weight, preterm infants. Pediatrics 85(3 Pt 2): 400-404, 1990

Changes in the developmental outcome of very low and extremely low birth weight infants at 24 months' corrected age born in 1997-2007. Ceska Gynekologie 75(5): 455-461, 2011

Trends in low birth weight and preterm birth among island-born and state-born Puerto Rican infants, 1990-2000. American Journal of Epidemiology 157(11 Supplement): S104, June 1, 2003

Two-year neurodevelopmental outcome of preterm born children ≤ 750 g at birth. Archives of Disease in Childhood. Fetal and Neonatal Edition 96(3): F169-F177, 2011

Neurodevelopmental outcome over time of preterm born children ≤750 g at birth. Early Human Development 87(3): 183-191, 2011