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Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging



Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging



Journal of Computer Assisted Tomography 37(2): 247-251



The quantification of cerebral blood flow using pulsed arterial spin labeling could be erroneous with a nonoptimal inversion time (TI). We suggest that the optimal individual TI is dependent on the hemodynamic values of the supra-aortic vessels. Twenty-two healthy volunteers (mean age, 31.8 years) underwent 7 pulsed arterial spin labeling scans at 3 T with TI ranging from 1200 to 1800 milliseconds every 100 milliseconds. The quantitative hemodynamic values of carotids were computed using a cine phase-contrast sequence. Optimal TIs were determined using visual and quantitative criteria. A correlation was sought between each optimal individual TI criterion and the hemodynamic parameter values. The optimal group TI was 1700 milliseconds. The individual analysis showed a significant correlation between the optimal TI of white matter signal-to-noise ratio and stroke distance, and the optimal TI of contrast-to-noise ratio with mean velocity. A correlation was found between optimal individual TIs and carotid hemodynamic parameters.

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Accession: 054769166

Download citation: RISBibTeXText

PMID: 23493214

DOI: 10.1097/RCT.0b013e31827cd548


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