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Physiological characteristics of crab Portunus sanguinolentus egg mass extract from southeast coast of India



Physiological characteristics of crab Portunus sanguinolentus egg mass extract from southeast coast of India



Journal of Basic and Clinical Physiology and Pharmacology 26(3): 265-273



The present investigation was undertaken to evaluate the physiological characteristics of crab egg mass (Portunus sanguinolentus) crude extract. Assays were followed by standard methods. A maximum of 256 hemolytic units (HU) and a minimum of 128 HU were found in chicken and goat erythrocytes. In an antimicrobial assay, Salmonella paratyphi and Aspergillus niger showed most susceptibility (8.0 mm and 13.0 mm) against n-butanol extracts. In the tail flick method, 5.33±0.19* AR the maximum analgesic response was recorded 30 min after the administration of crude extract (150 mg kg-1). In the hot plate method, 5.13±0.13* AR maximum paw licking was recorded 15 min after the administration of crude extract (150 mg kg-1). In an anti-inflammatory assay, 0.31±0.23* anti-inflammatory response and inhibition of paw edema 39.22% were observed 1 h after the administration of crude extract (250 mg kg-1). Primary structural groups gained through Fourier transformed infrared (FTIR) analysis peaks were observed and assigned as amide groups I (1517.81-1633.12 cm-1), II (1446.58-1517.81 cm-1) and III (1342.47-1406.85 cm-1). The results indicate that crab egg masses have remarkable antimicrobial, hemolytic and cytotoxic activities.

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Accession: 055001493

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PMID: 25423672

DOI: 10.1515/jbcpp-2013-0133


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