+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells

Plant CLE peptides from two distinct functional classes synergistically induce division of vascular cells

Proceedings of the National Academy of Sciences of the United States of America 105(47): 18625-18630

ISSN/ISBN: 0027-8424

PMID: 19011104

DOI: 10.1073/pnas.0809395105

The Clavata3 (CLV3)/endosperm surrounding region (CLE) signaling peptides are encoded in large plant gene families. CLV3 and the other A-type CLE peptides promote cell differentiation in root and shoot apical meristems, whereas the B-type peptides (CLE41-CLE44) do not. Instead, CLE41 inhibits the differentiation of Zinnia elegans tracheary elements. To test whether CLE genes might code for antagonistic or synergistic functions, peptides from both types were combined through overexpression within or application onto Arabidopsis thaliana seedlings. The CLE41 peptide (CLE41p) promoted proliferation of vascular cells, although delaying differentiation into phloem and xylem cell lineages. Application of CLE41p or overexpression of CLE41 did not suppress the terminal differentiation of the root and shoot apices triggered by A-type CLE peptides. However, in combination, A-type peptides enhanced all of the phenotypes associated with CLE41 gain-of-function, leading to massive proliferation of vascular cells. This proliferation relied on auxin signaling because it was enhanced by exogenous application of a synthetic auxin, decreased by an auxin polar transport inhibitor, and abolished by a mutation in the Monopteros auxin response factor. These findings highlight that vascular patterning is a process controlled in time and space by different CLE peptides in conjunction with hormonal signaling.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055016303

Download citation: RISBibTeXText

Related references

Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin. Iscience 23(12): 101785, 2020

Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacytoid dendritic cells. Clinical and Diagnostic Laboratory Immunology 12(5): 606-621, 2005

Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells. Circulation Research 97(5): 434-442, 2005

Interleukin-1b and tumor necrosis factor-a synergistically induce NO synthase in rat vascular smooth muscle cells. American Journal of Physiology 266: 203, 1994

Interleukin-1 beta and tumor necrosis factor-alpha synergistically induce NO synthase in rat vascular smooth muscle cells. American Journal of Physiology 266(4 Pt 2): R1197-R1203, 1994

Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic β-cells. Experimental and Therapeutic Medicine 18(4): 2592-2598, 2019

Cutting edge: distinct Toll-like receptor 2 activators selectively induce different classes of mediator production from human mast cells. Journal of Immunology 170(4): 1625-1629, 2003

Oxidized low-density lipoprotein acts synergistically with beta-glycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells. Journal of Cellular Biochemistry 105(1): 185-193, 2008

Division of cat retinal w cells into two functional classes based on quantitative analyses of their response properties. Society for Neuroscience Abstracts 15(2): 1394, 1989

Two distinct mechanisms induce apoptosis in human vascular endothelial cells. European Heart Journal 18(ABSTR Suppl. ): 610, 1997

Select Plant Tannins Induce Il-2R Up-Regulation and Augment Cell Division in T Cells. The Journal of Immunology 179(10): 6468-6478, 2007

Select Plant Tannins Induce IL-2Ra Up-Regulation and Augment Cell Division in g T Cells. Journal of Immunology 179(10): 68-78, 2007

Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity 39(3): 560-572, 2013

PTH and extracellular nucleotides synergistically induce c-fos expression in osteoblasts via distinct signal transduction pathways. Bone (New York) 17(6): 559, 1995

The atrial natriuretic peptides induce apoptosis in vascular smooth muscle cells. European Journal of Clinical Investigation 26(Suppl. 1): A6, 1996