+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Population-based seroprevalence of HSV-2 and syphilis in Andhra Pradesh state of India



Population-based seroprevalence of HSV-2 and syphilis in Andhra Pradesh state of India



Bmc Infectious Diseases 10: 59



Understanding the prevalence and risk factors for common causes of ulcerative genital disease in the general population would inform current STI syndromic management and HIV testing strategies in high HIV prevalence regions of India. Persons 15-49 years old from 32 rural and 34 urban clusters were sampled using a stratified random method to represent adults in the high HIV prevalence Guntur district in Andhra Pradesh state. Interviews were conducted and dry blood spots were collected on 12,617 study participants. Testing for HSV-2 and syphilis was performed. Adjusted HSV-2 and syphilis seroprevalence rates were 4.70% and 2.08% for men and 7.07% and 1.42% for women. For men, tattooing, >3 lifetime sex partners, tobacco use, and sex with men in the past 6 months were associated with HSV-2 or syphilis (ORs, 1.66-2.95, p < 0.05). Male circumcision was positively associated with HSV-2 infection (OR, 1.37, p = 0.028) though this could be due to residual confounding. In women, greater than one lifetime partner remained significantly associated with HSV-2 in multivariate analysis (OR, 2.61; 95% CI, 1.39-4.87). Among all behavioral risk factors and other covariates in women and men, HIV infection exhibited the strongest association with HSV-2 and syphilis (ORs, 8.2-14.2, p < 0.001). The proportion of individuals with HSV-2 who were HIV infected was less than the proportion with syphilis who were HIV infected (11.8% vs. 22.7%; p = 0.001). Nearly one in four persons surveyed in this population-based study that were seroprevalent for syphilis, were also HIV infected. Common population risk factors for syphilis, HSV-2 and HIV and high rates of co-seroprevalence suggest that HIV testing, STI testing and service strategies for these would benefit from direct linkage in India.

(PDF emailed within 0-6 h: $19.90)

Accession: 055055345

Download citation: RISBibTeXText

PMID: 20214795

DOI: 10.1186/1471-2334-10-59


Related references

A population-based assessment of presbyopia in the state of Andhra Pradesh, south India: the Andhra Pradesh Eye Disease Study. Investigative Ophthalmology and Visual Science 47(6): 2324-2328, 2006

Risk factors associated with HIV in a population-based study in Andhra Pradesh state of India. International Journal of Epidemiology 37(6): 1274-1286, 2008

Population-based assessment of prevalence and risk factors for pterygium in the South Indian state of Andhra Pradesh: the Andhra Pradesh Eye Disease Study. Investigative Ophthalmology and Visual Science 54(8): 5359-5366, 2013

Population-based assessment of refractive error in India: the Andhra Pradesh eye disease study. Clinical and Experimental Ophthalmology 30(2): 84-93, 2002

Bryo flora of andhra pradesh india iii marchantia palmata at araku valley a new plant record for andhra pradesh india abstract. Indian Science Congress Association Proceedings 54(3): 300, 1967

Type-specific seroprevalence of bluetongue in Andhra Pradesh, India, during 2005-2009. Indian Journal of Virology 24(3): 394-397, 2014

Prajateerpu: a Citizens Jury/Scenario Workshop on Food and Farming Futures for Andhra Pradesh, India, held at the Farmer Liaison Centre, Algole, Andhra Pradesh, India, 25 June - 1 July, 2001. Prajateerpu: a Citizens Jury/Scenario Workshop on Food and Farming Futures for Andhra Pradesh, India, held at the Farmer Liaison Centre, Algole, Andhra Pradesh, India, 25 June 1 July, 2001: vi + 74 pp., 2002

Predictors of HIV prevalence among street-based female sex workers in Andhra Pradesh state of India: a district-level analysis. Bmc Women's Health 14: 65, 2014

Population structure and genetic analysis of different utility types of mango Mangifera indica L germplasm of Andhra Pradesh state of India using microsatellite markers. 2013

Anthropometrics of mental foramen in dry dentate and edentulous mandibles in Coastal Andhra population of Andhra Pradesh State. Journal of Indian Society of Periodontology 18(4): 497-502, 2014

Caste-and tribe-specific Y-chromosome haplotypes based on Single Nucleotide Polymorphisms in seven endogamous population groups of Andhra Pradesh, South India. American Journal of Human Genetics 67(4 Supplement 2): 217, October, 2000

Design of a population-based study of visual impairment in India: The Andhra Pradesh Eye Disease Study. Indian Journal of Ophthalmology 45(4): 251-257, 1998

Condom use and prevalence of syphilis and HIV among female sex workers in Andhra Pradesh, India - following a large-scale HIV prevention intervention. Bmc Public Health 11 Suppl 6: S1, 2012

Population based outcomes of cataract surgery in three tribal areas of Andhra Pradesh, India: risk factors for poor outcomes. Plos One 7(5): E35701, 2012