+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Prevalence of drug-resistant opportunistic microorganisms in oral cavity after treatment for oral cancer

Prevalence of drug-resistant opportunistic microorganisms in oral cavity after treatment for oral cancer

Journal of Oral Science 55(2): 145-155

Drug-resistant opportunistic infections may cause health problems in immunocompromised hosts. Representative microorganisms in opportunistic infections of the oral cavity are Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. We investigated the prevalence of drug-resistant opportunistic microorganisms in elderly adults receiving follow-up examinations after primary treatment of oral cancer. Oral microorganisms were collected from patients satisfactorily treated for oral cancer (defined as good outcomes to date) and a group of healthy adults (controls). After identification of microorganisms, the prevalence of drug-resistant microorganisms was studied. Pulsed-field gel electrophoresis (PFGE) and staphylococcal cassette chromosome mec (SCCmec) typing were also performed for methicillin-resistant S aureus (MRSA). Statistical analysis revealed no significant differences in the prevalences of the three microorganisms between the groups. Surprisingly, 69.2% of S aureus isolates showed oxacillin resistance, suggesting that MRSA colonization is increasing among older Japanese. These MRSA isolates possessed SCCmec types II and IV but no representative toxin genes. Our results indicate that a basic infection control strategy, including standard precautions against MRSA, is important for elderly adults, particularly after treatment for oral cancer.

(PDF emailed within 1 workday: $29.90)

Accession: 055157361

Download citation: RISBibTeXText

PMID: 23748454

Related references

The sensitivity to antibiotics and disinfecting substances of opportunistic microorganisms isolated from the oral cavity of patients with orthodontic pathology. Stomatologiia 1991(6): 45-48, 1991

The prevention and treatment of oral cavity ulcer and infection of patients with oral cavity malignant cancer after chemotherapy. Shanghai Kou Qiang Yi Xue 4(3): 136-137, 1995

Influence of TNF-α blockers on the oral prevalence of opportunistic microorganisms in ankylosing spondylitis patients. Clinical and Experimental Rheumatology 30(5): 679-685, 2013

Relationships between activity of daily living, and oral cavity care and the number of oral cavity microorganisms in patients with cerebrovascular diseases. Journal of Medical Investigation 46(1-2): 79-85, 1999

Principles of neopl head and neck cancer treatment oral cavity hypopharynx larynx and major salivary glands human neopl oral cavity carcinomas lymphatic involvement. Southern Medical Bulletin 57(1): 116-123, 1969

T3 and T4 cancer of the oral cavity, surgical treatment with oral tongue resection. Annales d'Oto-Laryngologie et de Chirurgie Cervico Faciale 118(2): 74-79, 2001

Recovery of oral function following surgical treatment for an oral cavity cancer. Nederlands Tijdschrift Voor Tandheelkunde 114(8): 349-352, 2007

Oral cavity infection: an adverse effect after the treatment of oral cancer in aged individuals. Journal of Applied Oral Science 22(4): 261-267, 2014

Changes and predictors of radiation-induced oral mucositis in patients with oral cavity cancer during active treatment. European Journal of Oncology Nursing 19(3): 214-219, 2016

Analyses of beverage remains in drug rape cases revealing drug residues--the possibility of contamination from drug concentrated oral fluid or oral cavity contained tablets. Journal of Forensic Sciences 59(1): 208-210, 2014

Oral Health Interventions Using Chlorhexidine-Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trial. Journal of Evidence-Based Dental Practice 18(2): 99-109, 2018

Cryotherapy, combined drug therapy and radiotherapy in the treatment of oral cavity cancer: 3 years' experience. Minerva Stomatologica 29(5): 335-340, 1980

Association of Oral Human Papillomavirus DNA Persistence With Cancer Progression After Primary Treatment for Oral Cavity and Oropharyngeal Squamous Cell Carcinoma. JAMA Oncology 2019, 2019

Distant metastasis of cancer of the oral cavity; malignant tumor of the femur secondary to an epithelioma of the oral cavity clinically cured two years ago. La Presse Medicale 65(81): 1815-1817, 1957

An unusual case with bronchogenic carcinoma oral cavity metastasis or second primary oral cavity cancer?. European Respiratory Journal 12(SUPPL 28): 416S, Sept, 1998